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TRIM4 (tripartite motif containing 4)

Identity

Alias_namestripartite motif-containing 4
Alias_symbol (synonym)RNF87
Other alias
HGNC (Hugo) TRIM4
LocusID (NCBI) 89122
Atlas_Id 75153
Location 7q22.1  [Link to chromosome band 7q22]
Location_base_pair Starts at 99890407 and ends at 99919600 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
SMURF1 (7q22.1) / TRIM4 (7q22.1)TRIM4 (7q22.1) / TAF6 (7q22.1)TRIM4 (7q22.1) / TRIM4 (7q22.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)TRIM4   16275
Cards
Entrez_Gene (NCBI)TRIM4  89122  tripartite motif containing 4
AliasesRNF87
GeneCards (Weizmann)TRIM4
Ensembl hg19 (Hinxton)ENSG00000146833 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000146833 [Gene_View]  chr7:99890407-99919600 [Contig_View]  TRIM4 [Vega]
ICGC DataPortalENSG00000146833
TCGA cBioPortalTRIM4
AceView (NCBI)TRIM4
Genatlas (Paris)TRIM4
WikiGenes89122
SOURCE (Princeton)TRIM4
Genetics Home Reference (NIH)TRIM4
Genomic and cartography
GoldenPath hg38 (UCSC)TRIM4  -     chr7:99890407-99919600 -  7q22.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TRIM4  -     7q22.1   [Description]    (hg19-Feb_2009)
EnsemblTRIM4 - 7q22.1 [CytoView hg19]  TRIM4 - 7q22.1 [CytoView hg38]
Mapping of homologs : NCBITRIM4 [Mapview hg19]  TRIM4 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AF220023 AF220024 AK092892 AK293565 BC011763
RefSeq transcript (Entrez)NM_033017 NM_033091
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)TRIM4
Cluster EST : UnigeneHs.50749 [ NCBI ]
CGAP (NCI)Hs.50749
Alternative Splicing GalleryENSG00000146833
Gene ExpressionTRIM4 [ NCBI-GEO ]   TRIM4 [ EBI - ARRAY_EXPRESS ]   TRIM4 [ SEEK ]   TRIM4 [ MEM ]
Gene Expression Viewer (FireBrowse)TRIM4 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)89122
GTEX Portal (Tissue expression)TRIM4
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9C037   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9C037  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9C037
Splice isoforms : SwissVarQ9C037
Catalytic activity : Enzyme2.3.2.27 [ Enzyme-Expasy ]   2.3.2.272.3.2.27 [ IntEnz-EBI ]   2.3.2.27 [ BRENDA ]   2.3.2.27 [ KEGG ]   
PhosPhoSitePlusQ9C037
Domaine pattern : Prosite (Expaxy)B302_SPRY (PS50188)    ZF_BBOX (PS50119)    ZF_RING_1 (PS00518)    ZF_RING_2 (PS50089)   
Domains : Interpro (EBI)B30.2/SPRY    Butyrophylin    ConA-like_dom    SPRY_dom    Znf_B-box    Znf_RING    Znf_RING/FYVE/PHD    Znf_RING_CS   
Domain families : Pfam (Sanger)SPRY (PF00622)    zf-B_box (PF00643)   
Domain families : Pfam (NCBI)pfam00622    pfam00643   
Domain families : Smart (EMBL)BBOX (SM00336)  RING (SM00184)  SPRY (SM00449)  
Conserved Domain (NCBI)TRIM4
DMDM Disease mutations89122
Blocks (Seattle)TRIM4
SuperfamilyQ9C037
Human Protein AtlasENSG00000146833
Peptide AtlasQ9C037
HPRD15556
IPIIPI00030371   IPI00011551   IPI00410582   IPI01009282   IPI00926997   
Protein Interaction databases
DIP (DOE-UCLA)Q9C037
IntAct (EBI)Q9C037
FunCoupENSG00000146833
BioGRIDTRIM4
STRING (EMBL)TRIM4
ZODIACTRIM4
Ontologies - Pathways
QuickGOQ9C037
Ontology : AmiGOcytoplasm  cytosol  plasma membrane  zinc ion binding  protein ubiquitination  transferase activity  innate immune response  protein trimerization  
Ontology : EGO-EBIcytoplasm  cytosol  plasma membrane  zinc ion binding  protein ubiquitination  transferase activity  innate immune response  protein trimerization  
NDEx NetworkTRIM4
Atlas of Cancer Signalling NetworkTRIM4
Wikipedia pathwaysTRIM4
Orthology - Evolution
OrthoDB89122
GeneTree (enSembl)ENSG00000146833
Phylogenetic Trees/Animal Genes : TreeFamTRIM4
HOVERGENQ9C037
HOGENOMQ9C037
Homologs : HomoloGeneTRIM4
Homology/Alignments : Family Browser (UCSC)TRIM4
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTRIM4 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TRIM4
dbVarTRIM4
ClinVarTRIM4
1000_GenomesTRIM4 
Exome Variant ServerTRIM4
ExAC (Exome Aggregation Consortium)TRIM4 (select the gene name)
Genetic variants : HAPMAP89122
Genomic Variants (DGV)TRIM4 [DGVbeta]
DECIPHERTRIM4 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTRIM4 
Mutations
ICGC Data PortalTRIM4 
TCGA Data PortalTRIM4 
Broad Tumor PortalTRIM4
OASIS PortalTRIM4 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTRIM4  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDTRIM4
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch TRIM4
DgiDB (Drug Gene Interaction Database)TRIM4
DoCM (Curated mutations)TRIM4 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)TRIM4 (select a term)
intoGenTRIM4
Cancer3DTRIM4(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
MedgenTRIM4
Genetic Testing Registry TRIM4
NextProtQ9C037 [Medical]
TSGene89122
GENETestsTRIM4
Target ValidationTRIM4
Huge Navigator TRIM4 [HugePedia]
snp3D : Map Gene to Disease89122
BioCentury BCIQTRIM4
ClinGenTRIM4
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD89122
Chemical/Pharm GKB GenePA38108
Clinical trialTRIM4
Miscellaneous
canSAR (ICR)TRIM4 (select the gene name)
Probes
Litterature
PubMed19 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTRIM4
EVEXTRIM4
GoPubMedTRIM4
iHOPTRIM4
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 18 13:42:31 CEST 2017

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