TRIM40 (tripartite motif containing 40)

2011-10-01 Affiliation

Identity

HGNC

TRIM40

LOCATION

6p22.1

LOCUSID

135644

ALIAS

RNF35

FUSION GENES

Show Gene Fusions

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 135644
MIM: 616976
HGNC: 18736
Ensembl: ENSG00000204614

Variants:

dbSNP: 135644
ClinVar: 135644
TCGA: ENSG00000204614
COSMIC: TRIM40

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000204614	ENST00000307859	Q6P9F5
ENSG00000204614	ENST00000376724	Q6P9F5
ENSG00000204614	ENST00000376724	A0A1U9X8U1
ENSG00000204614	ENST00000396581	Q6P9F5
ENSG00000204614	ENST00000396581	A0A1U9X8U1

Expression (GTEx)

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

Protein levels (Protein atlas)

Not detected

Low

Medium

High

References

Pubmed ID	Year	Title	Citations
19851445	2009	High-density SNP screening of the major histocompatibility complex in systemic lupus erythematosus demonstrates strong evidence for independent susceptibility regions.	51
21474709	2011	TRIM40 promotes neddylation of IKKγ and is downregulated in gastrointestinal cancers.	24
20593013	2010	A major histocompatibility Class I locus contributes to multiple sclerosis susceptibility independently from HLA-DRB1*15:01.	20

Citation

Dessen P

TRIM40 (tripartite motif containing 40)

Atlas Genet Cytogenet Oncol Haematol. 2011-10-01

Online version: http://atlasgeneticsoncology.org/gene/52416/trim40