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TRIM40 (tripartite motif containing 40)

Identity

Alias (NCBI)RNF35
HGNC (Hugo) TRIM40
HGNC Alias symbRNF35
HGNC Previous nametripartite motif-containing 40
LocusID (NCBI) 135644
Atlas_Id 52416
Location 6p22.1  [Link to chromosome band 6p22]
Location_base_pair Starts at 30136733 and ends at 30148735 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
MED15 (22q11.21) / TRIM40 (6p22.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

Nomenclature
HGNC (Hugo)TRIM40   18736
Cards
Entrez_Gene (NCBI)TRIM40    tripartite motif containing 40
AliasesRNF35
GeneCards (Weizmann)TRIM40
Ensembl hg19 (Hinxton)ENSG00000204614 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000204614 [Gene_View]  ENSG00000204614 [Sequence]  chr6:30136733-30148735 [Contig_View]  TRIM40 [Vega]
ICGC DataPortalENSG00000204614
TCGA cBioPortalTRIM40
AceView (NCBI)TRIM40
Genatlas (Paris)TRIM40
SOURCE (Princeton)TRIM40
Genetics Home Reference (NIH)TRIM40
Genomic and cartography
GoldenPath hg38 (UCSC)TRIM40  -     chr6:30136733-30148735 +  6p22.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TRIM40  -     6p22.1   [Description]    (hg19-Feb_2009)
GoldenPathTRIM40 - 6p22.1 [CytoView hg19]  TRIM40 - 6p22.1 [CytoView hg38]
ImmunoBaseENSG00000204614
genome Data Viewer NCBITRIM40 [Mapview hg19]  
OMIM616976   
Gene and transcription
Genbank (Entrez)AF489517 BC060785 CB990357
RefSeq transcript (Entrez)NM_001286633 NM_138700
RefSeq genomic (Entrez)NC_000006 NG_033972 NT_113891 NT_167244 NT_167245 NT_167246 NT_167247 NT_167248 NT_167249
Consensus coding sequences : CCDS (NCBI)TRIM40
Alternative Splicing GalleryENSG00000204614
Gene ExpressionTRIM40 [ NCBI-GEO ]   TRIM40 [ EBI - ARRAY_EXPRESS ]   TRIM40 [ SEEK ]   TRIM40 [ MEM ]
Gene Expression Viewer (FireBrowse)TRIM40 [ Firebrowse - Broad ]
GenevisibleExpression of TRIM40 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)135644
GTEX Portal (Tissue expression)TRIM40
Human Protein AtlasENSG00000204614-TRIM40 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ6P9F5   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ6P9F5  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ6P9F5
Splice isoforms : SwissVarQ6P9F5
PhosPhoSitePlusQ6P9F5
Domaine pattern : Prosite (Expaxy)ZF_BBOX (PS50119)    ZF_RING_1 (PS00518)    ZF_RING_2 (PS50089)   
Domains : Interpro (EBI)Znf_B-box    Znf_C3HC4_RING-type    Znf_RING    Znf_RING/FYVE/PHD    Znf_RING_CS   
Domain families : Pfam (Sanger)zf-C3HC4 (PF00097)   
Domain families : Pfam (NCBI)pfam00097   
Domain families : Smart (EMBL)RING (SM00184)  
Conserved Domain (NCBI)TRIM40
Blocks (Seattle)TRIM40
SuperfamilyQ6P9F5
Human Protein Atlas [tissue]ENSG00000204614-TRIM40 [tissue]
Peptide AtlasQ6P9F5
HPRD15557
IPIIPI00477194   IPI00152496   IPI00894215   IPI00894114   IPI00893026   IPI00893135   
Protein Interaction databases
DIP (DOE-UCLA)Q6P9F5
IntAct (EBI)Q6P9F5
BioGRIDTRIM40
STRING (EMBL)TRIM40
ZODIACTRIM40
Ontologies - Pathways
QuickGOQ6P9F5
Ontology : AmiGOprotein binding  cytoplasm  zinc ion binding  IkappaB kinase complex  regulation of gene expression  protein ubiquitination  negative regulation of cell growth  negative regulation of NF-kappaB transcription factor activity  negative regulation of NF-kappaB transcription factor activity  negative regulation of protein catabolic process  innate immune response  protein neddylation  ubiquitin protein ligase activity  negative regulation of protein localization to nucleus  negative regulation of NIK/NF-kappaB signaling  
Ontology : EGO-EBIprotein binding  cytoplasm  zinc ion binding  IkappaB kinase complex  regulation of gene expression  protein ubiquitination  negative regulation of cell growth  negative regulation of NF-kappaB transcription factor activity  negative regulation of NF-kappaB transcription factor activity  negative regulation of protein catabolic process  innate immune response  protein neddylation  ubiquitin protein ligase activity  negative regulation of protein localization to nucleus  negative regulation of NIK/NF-kappaB signaling  
NDEx NetworkTRIM40
Atlas of Cancer Signalling NetworkTRIM40
Wikipedia pathwaysTRIM40
Orthology - Evolution
OrthoDB135644
GeneTree (enSembl)ENSG00000204614
Phylogenetic Trees/Animal Genes : TreeFamTRIM40
HOGENOMQ6P9F5
Homologs : HomoloGeneTRIM40
Homology/Alignments : Family Browser (UCSC)TRIM40
Gene fusions - Rearrangements
Fusion : QuiverTRIM40
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTRIM40 [hg38]
dbVarTRIM40
ClinVarTRIM40
MonarchTRIM40
1000_GenomesTRIM40 
Exome Variant ServerTRIM40
GNOMAD BrowserENSG00000204614
Varsome BrowserTRIM40
Genomic Variants (DGV)TRIM40 [DGVbeta]
DECIPHERTRIM40 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTRIM40 
Mutations
ICGC Data PortalTRIM40 
TCGA Data PortalTRIM40 
Broad Tumor PortalTRIM40
OASIS PortalTRIM40 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTRIM40  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DTRIM40
Mutations and Diseases : HGMDTRIM40
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch TRIM40
DgiDB (Drug Gene Interaction Database)TRIM40
DoCM (Curated mutations)TRIM40 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)TRIM40 (select a term)
intoGenTRIM40
Cancer3DTRIM40(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM616976   
Orphanet
DisGeNETTRIM40
MedgenTRIM40
Genetic Testing Registry TRIM40
NextProtQ6P9F5 [Medical]
GENETestsTRIM40
Target ValidationTRIM40
Huge Navigator TRIM40 [HugePedia]
ClinGenTRIM40
Clinical trials, drugs, therapy
MyCancerGenomeTRIM40
Protein Interactions : CTD
Pharm GKB GenePA38663
Clinical trialTRIM40
Miscellaneous
canSAR (ICR)TRIM40 (select the gene name)
HarmonizomeTRIM40
DataMed IndexTRIM40
Probes
Litterature
PubMed12 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXTRIM40
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Sat Dec 5 21:14:50 CET 2020

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