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TRIM46 (tripartite motif containing 46)

Identity

Alias (NCBI)GENEY
TRIFIC
HGNC (Hugo) TRIM46
HGNC Alias symbFLJ23229
TRIFIC
HGNC Previous nametripartite motif-containing 46
LocusID (NCBI) 80128
Atlas_Id 75159
Location 1q22  [Link to chromosome band 1q22]
Location_base_pair Starts at 155173849 and ends at 155184970 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
AZIN1 (8q22.3) / TRIM46 (1q22)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)TRIM46   19019
Cards
Entrez_Gene (NCBI)TRIM46    tripartite motif containing 46
AliasesGENEY; TRIFIC
GeneCards (Weizmann)TRIM46
Ensembl hg19 (Hinxton)ENSG00000163462 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000163462 [Gene_View]  ENSG00000163462 [Sequence]  chr1:155173849-155184970 [Contig_View]  TRIM46 [Vega]
ICGC DataPortalENSG00000163462
TCGA cBioPortalTRIM46
AceView (NCBI)TRIM46
Genatlas (Paris)TRIM46
SOURCE (Princeton)TRIM46
Genetics Home Reference (NIH)TRIM46
Genomic and cartography
GoldenPath hg38 (UCSC)TRIM46  -     chr1:155173849-155184970 +  1q22   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TRIM46  -     1q22   [Description]    (hg19-Feb_2009)
GoldenPathTRIM46 - 1q22 [CytoView hg19]  TRIM46 - 1q22 [CytoView hg38]
ImmunoBaseENSG00000163462
Genome Data Viewer NCBITRIM46 [Mapview hg19]  
OMIM600986   
Gene and transcription
Genbank (Entrez)AK026882 AK090504 AK096158 AK128139 AK225075
RefSeq transcript (Entrez)NM_001256599 NM_001256600 NM_001256601 NM_001282378 NM_001282379 NM_025058
Consensus coding sequences : CCDS (NCBI)TRIM46
Gene ExpressionTRIM46 [ NCBI-GEO ]   TRIM46 [ EBI - ARRAY_EXPRESS ]   TRIM46 [ SEEK ]   TRIM46 [ MEM ]
Gene Expression Viewer (FireBrowse)TRIM46 [ Firebrowse - Broad ]
GenevisibleExpression of TRIM46 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)80128
GTEX Portal (Tissue expression)TRIM46
Human Protein AtlasENSG00000163462-TRIM46 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ7Z4K8   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ7Z4K8  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ7Z4K8
PhosPhoSitePlusQ7Z4K8
Domaine pattern : Prosite (Expaxy)B302_SPRY (PS50188)    COS (PS51262)    FN3 (PS50853)    ZF_BBOX (PS50119)    ZF_RING_1 (PS00518)   
Domains : Interpro (EBI)B30.2/SPRY    B30.2/SPRY_sf    ConA-like_dom_sf    COS_domain    FN3_dom    FN3_sf    Ig-like_fold    Midline-1_COS    SPRY/PRY_TRIM46    Znf-RING_LisH    Znf_B-box    Znf_RING    Znf_RING_CS   
Domain families : Pfam (Sanger)COS (PF18568)    zf-B_box (PF00643)    zf-RING_UBOX (PF13445)   
Domain families : Pfam (NCBI)pfam18568    pfam00643    pfam13445   
Domain families : Smart (EMBL)BBOX (SM00336)  RING (SM00184)  
Conserved Domain (NCBI)TRIM46
SuperfamilyQ7Z4K8
AlphaFold pdb e-kbQ7Z4K8   
Human Protein Atlas [tissue]ENSG00000163462-TRIM46 [tissue]
HPRD15563
Protein Interaction databases
DIP (DOE-UCLA)Q7Z4K8
IntAct (EBI)Q7Z4K8
BioGRIDTRIM46
STRING (EMBL)TRIM46
ZODIACTRIM46
Ontologies - Pathways
QuickGOQ7Z4K8
Ontology : AmiGOmicrotubule bundle formation  neuron migration  cytoskeleton  axonogenesis  zinc ion binding  negative regulation of axon extension  axon initial segment  main axon  anterograde synaptic vesicle transport  protein localization to axon  positive regulation of anterograde dense core granule transport  regulation of cellular protein localization  axon cytoplasm  proximal neuron projection  
Ontology : EGO-EBImicrotubule bundle formation  neuron migration  cytoskeleton  axonogenesis  zinc ion binding  negative regulation of axon extension  axon initial segment  main axon  anterograde synaptic vesicle transport  protein localization to axon  positive regulation of anterograde dense core granule transport  regulation of cellular protein localization  axon cytoplasm  proximal neuron projection  
NDEx NetworkTRIM46
Atlas of Cancer Signalling NetworkTRIM46
Wikipedia pathwaysTRIM46
Orthology - Evolution
OrthoDB80128
GeneTree (enSembl)ENSG00000163462
Phylogenetic Trees/Animal Genes : TreeFamTRIM46
Homologs : HomoloGeneTRIM46
Homology/Alignments : Family Browser (UCSC)TRIM46
Gene fusions - Rearrangements
Fusion : QuiverTRIM46
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTRIM46 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TRIM46
dbVarTRIM46
ClinVarTRIM46
MonarchTRIM46
1000_GenomesTRIM46 
Exome Variant ServerTRIM46
GNOMAD BrowserENSG00000163462
Varsome BrowserTRIM46
ACMGTRIM46 variants
VarityQ7Z4K8
Genomic Variants (DGV)TRIM46 [DGVbeta]
DECIPHERTRIM46 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTRIM46 
Mutations
ICGC Data PortalTRIM46 
TCGA Data PortalTRIM46 
Broad Tumor PortalTRIM46
OASIS PortalTRIM46 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTRIM46  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DTRIM46
Mutations and Diseases : HGMDTRIM46
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaTRIM46
DgiDB (Drug Gene Interaction Database)TRIM46
DoCM (Curated mutations)TRIM46
CIViC (Clinical Interpretations of Variants in Cancer)TRIM46
Cancer3DTRIM46
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM600986   
Orphanet
DisGeNETTRIM46
MedgenTRIM46
Genetic Testing Registry TRIM46
NextProtQ7Z4K8 [Medical]
GENETestsTRIM46
Target ValidationTRIM46
Huge Navigator TRIM46 [HugePedia]
ClinGenTRIM46
Clinical trials, drugs, therapy
MyCancerGenomeTRIM46
Protein Interactions : CTDTRIM46
Pharm GKB GenePA134914315
PharosQ7Z4K8
Clinical trialTRIM46
Miscellaneous
canSAR (ICR)TRIM46
HarmonizomeTRIM46
DataMed IndexTRIM46
Probes
Litterature
PubMed20 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXTRIM46
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 16:26:54 CEST 2021

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