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TRIM54 (tripartite motif containing 54)

Identity

Alias_namesRNF30
ring finger protein 30
tripartite motif-containing 54
Alias_symbol (synonym)MURF
MURF-3
Other aliasmuRF3
HGNC (Hugo) TRIM54
LocusID (NCBI) 57159
Atlas_Id 47121
Location 2p23.3  [Link to chromosome band 2p23]
Location_base_pair Starts at 27282429 and ends at 27307439 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
ENOSF1 (18p11.32) / TRIM54 (2p23.3)WDR43 (2p23.2) / TRIM54 (2p23.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)TRIM54   16008
Cards
Entrez_Gene (NCBI)TRIM54  57159  tripartite motif containing 54
AliasesMURF; MURF-3; RNF30; muRF3
GeneCards (Weizmann)TRIM54
Ensembl hg19 (Hinxton)ENSG00000138100 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000138100 [Gene_View]  chr2:27282429-27307439 [Contig_View]  TRIM54 [Vega]
ICGC DataPortalENSG00000138100
TCGA cBioPortalTRIM54
AceView (NCBI)TRIM54
Genatlas (Paris)TRIM54
WikiGenes57159
SOURCE (Princeton)TRIM54
Genetics Home Reference (NIH)TRIM54
Genomic and cartography
GoldenPath hg38 (UCSC)TRIM54  -     chr2:27282429-27307439 +  2p23.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TRIM54  -     2p23.3   [Description]    (hg19-Feb_2009)
EnsemblTRIM54 - 2p23.3 [CytoView hg19]  TRIM54 - 2p23.3 [CytoView hg38]
Mapping of homologs : NCBITRIM54 [Mapview hg19]  TRIM54 [Mapview hg38]
OMIM606474   
Gene and transcription
Genbank (Entrez)AJ291714 AJ291714 AK300699 BC141807 BF829678
RefSeq transcript (Entrez)NM_032546 NM_187841
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)TRIM54
Cluster EST : UnigeneHs.516036 [ NCBI ]
CGAP (NCI)Hs.516036
Alternative Splicing GalleryENSG00000138100
Gene ExpressionTRIM54 [ NCBI-GEO ]   TRIM54 [ EBI - ARRAY_EXPRESS ]   TRIM54 [ SEEK ]   TRIM54 [ MEM ]
Gene Expression Viewer (FireBrowse)TRIM54 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)57159
GTEX Portal (Tissue expression)TRIM54
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9BYV2   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9BYV2  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9BYV2
Splice isoforms : SwissVarQ9BYV2
PhosPhoSitePlusQ9BYV2
Domaine pattern : Prosite (Expaxy)COS (PS51262)    ZF_BBOX (PS50119)    ZF_RING_1 (PS00518)    ZF_RING_2 (PS50089)   
Domains : Interpro (EBI)COS_domain    TRIM54    Znf-RING_LisH    Znf_B-box    Znf_RING    Znf_RING/FYVE/PHD    Znf_RING_CS   
Domain families : Pfam (Sanger)zf-B_box (PF00643)    zf-RING_UBOX (PF13445)   
Domain families : Pfam (NCBI)pfam00643    pfam13445   
Domain families : Smart (EMBL)BBOX (SM00336)  RING (SM00184)  
Conserved Domain (NCBI)TRIM54
DMDM Disease mutations57159
Blocks (Seattle)TRIM54
PDB (SRS)3Q1D   
PDB (PDBSum)3Q1D   
PDB (IMB)3Q1D   
PDB (RSDB)3Q1D   
Structural Biology KnowledgeBase3Q1D   
SCOP (Structural Classification of Proteins)3Q1D   
CATH (Classification of proteins structures)3Q1D   
SuperfamilyQ9BYV2
Human Protein AtlasENSG00000138100
Peptide AtlasQ9BYV2
HPRD05928
IPIIPI00376605   IPI00000182   IPI00910314   
Protein Interaction databases
DIP (DOE-UCLA)Q9BYV2
IntAct (EBI)Q9BYV2
FunCoupENSG00000138100
BioGRIDTRIM54
STRING (EMBL)TRIM54
ZODIACTRIM54
Ontologies - Pathways
QuickGOQ9BYV2
Ontology : AmiGOsignal transducer activity  protein binding  microtubule  microtubule associated complex  microtubule-based process  negative regulation of microtubule depolymerization  signal transduction  multicellular organism development  microtubule binding  zinc ion binding  Z disc  muscle cell development  
Ontology : EGO-EBIsignal transducer activity  protein binding  microtubule  microtubule associated complex  microtubule-based process  negative regulation of microtubule depolymerization  signal transduction  multicellular organism development  microtubule binding  zinc ion binding  Z disc  muscle cell development  
NDEx NetworkTRIM54
Atlas of Cancer Signalling NetworkTRIM54
Wikipedia pathwaysTRIM54
Orthology - Evolution
OrthoDB57159
GeneTree (enSembl)ENSG00000138100
Phylogenetic Trees/Animal Genes : TreeFamTRIM54
HOVERGENQ9BYV2
HOGENOMQ9BYV2
Homologs : HomoloGeneTRIM54
Homology/Alignments : Family Browser (UCSC)TRIM54
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTRIM54 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TRIM54
dbVarTRIM54
ClinVarTRIM54
1000_GenomesTRIM54 
Exome Variant ServerTRIM54
ExAC (Exome Aggregation Consortium)TRIM54 (select the gene name)
Genetic variants : HAPMAP57159
Genomic Variants (DGV)TRIM54 [DGVbeta]
DECIPHERTRIM54 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTRIM54 
Mutations
ICGC Data PortalTRIM54 
TCGA Data PortalTRIM54 
Broad Tumor PortalTRIM54
OASIS PortalTRIM54 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTRIM54  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDTRIM54
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch TRIM54
DgiDB (Drug Gene Interaction Database)TRIM54
DoCM (Curated mutations)TRIM54 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)TRIM54 (select a term)
intoGenTRIM54
Cancer3DTRIM54(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM606474   
Orphanet
MedgenTRIM54
Genetic Testing Registry TRIM54
NextProtQ9BYV2 [Medical]
TSGene57159
GENETestsTRIM54
Target ValidationTRIM54
Huge Navigator TRIM54 [HugePedia]
snp3D : Map Gene to Disease57159
BioCentury BCIQTRIM54
ClinGenTRIM54
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD57159
Chemical/Pharm GKB GenePA34434
Clinical trialTRIM54
Miscellaneous
canSAR (ICR)TRIM54 (select the gene name)
Probes
Litterature
PubMed16 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTRIM54
EVEXTRIM54
GoPubMedTRIM54
iHOPTRIM54
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Jun 7 13:00:53 CEST 2017

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