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TRIM59 (tripartite motif containing 59)

Identity

Alias_namesTRIM57
tripartite motif-containing 57
tripartite motif-containing 59
Alias_symbol (synonym)TSBF1
Mrf1
RNF104
Other aliasIFT80L
MRF1
HGNC (Hugo) TRIM59
LocusID (NCBI) 286827
Atlas_Id 42711
Location 3q25.33  [Link to chromosome band 3q25]
Location_base_pair Starts at 160153291 and ends at 160167626 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
TRIM59 (3q25.33) / IFT80 (3q25.33)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)TRIM59   30834
Cards
Entrez_Gene (NCBI)TRIM59  286827  tripartite motif containing 59
AliasesIFT80L; MRF1; RNF104; TRIM57; 
TSBF1
GeneCards (Weizmann)TRIM59
Ensembl hg19 (Hinxton)ENSG00000213186 [Gene_View]  chr3:160153291-160167626 [Contig_View]  TRIM59 [Vega]
Ensembl hg38 (Hinxton)ENSG00000213186 [Gene_View]  chr3:160153291-160167626 [Contig_View]  TRIM59 [Vega]
ICGC DataPortalENSG00000213186
TCGA cBioPortalTRIM59
AceView (NCBI)TRIM59
Genatlas (Paris)TRIM59
WikiGenes286827
SOURCE (Princeton)TRIM59
Genetics Home Reference (NIH)TRIM59
Genomic and cartography
GoldenPath hg19 (UCSC)TRIM59  -     chr3:160153291-160167626 -  3q25.33   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)TRIM59  -     3q25.33   [Description]    (hg38-Dec_2013)
EnsemblTRIM59 - 3q25.33 [CytoView hg19]  TRIM59 - 3q25.33 [CytoView hg38]
Mapping of homologs : NCBITRIM59 [Mapview hg19]  TRIM59 [Mapview hg38]
OMIM616148   
Gene and transcription
Genbank (Entrez)AI215011 AK291284 AY159379 BC109259 BC109260
RefSeq transcript (Entrez)NM_173084
RefSeq genomic (Entrez)NC_000003 NC_018914 NT_005612 NW_004929311
Consensus coding sequences : CCDS (NCBI)TRIM59
Cluster EST : UnigeneHs.212957 [ NCBI ]
CGAP (NCI)Hs.212957
Alternative Splicing GalleryENSG00000213186
Gene ExpressionTRIM59 [ NCBI-GEO ]   TRIM59 [ EBI - ARRAY_EXPRESS ]   TRIM59 [ SEEK ]   TRIM59 [ MEM ]
Gene Expression Viewer (FireBrowse)TRIM59 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)286827
GTEX Portal (Tissue expression)TRIM59
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8IWR1   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8IWR1  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8IWR1
Splice isoforms : SwissVarQ8IWR1
PhosPhoSitePlusQ8IWR1
Domaine pattern : Prosite (Expaxy)ZF_BBOX (PS50119)    ZF_RING_1 (PS00518)    ZF_RING_2 (PS50089)   
Domains : Interpro (EBI)Znf_B-box    Znf_RING    Znf_RING/FYVE/PHD    Znf_RING_CS   
Domain families : Pfam (Sanger)zf-B_box (PF00643)    zf-RING_2 (PF13639)   
Domain families : Pfam (NCBI)pfam00643    pfam13639   
Domain families : Smart (EMBL)RING (SM00184)  
Conserved Domain (NCBI)TRIM59
DMDM Disease mutations286827
Blocks (Seattle)TRIM59
SuperfamilyQ8IWR1
Human Protein AtlasENSG00000213186
Peptide AtlasQ8IWR1
HPRD15568
IPIIPI00432462   IPI00947059   IPI00945336   IPI00947483   IPI00946493   IPI00945495   IPI00946347   
Protein Interaction databases
DIP (DOE-UCLA)Q8IWR1
IntAct (EBI)Q8IWR1
FunCoupENSG00000213186
BioGRIDTRIM59
STRING (EMBL)TRIM59
ZODIACTRIM59
Ontologies - Pathways
QuickGOQ8IWR1
Ontology : AmiGOprotein binding  endoplasmic reticulum  endoplasmic reticulum membrane  centrosome  cilium  zinc ion binding  integral component of membrane  intraciliary transport particle B  cilium assembly  negative regulation of I-kappaB kinase/NF-kappaB signaling  
Ontology : EGO-EBIprotein binding  endoplasmic reticulum  endoplasmic reticulum membrane  centrosome  cilium  zinc ion binding  integral component of membrane  intraciliary transport particle B  cilium assembly  negative regulation of I-kappaB kinase/NF-kappaB signaling  
NDEx NetworkTRIM59
Atlas of Cancer Signalling NetworkTRIM59
Wikipedia pathwaysTRIM59
Orthology - Evolution
OrthoDB286827
GeneTree (enSembl)ENSG00000213186
Phylogenetic Trees/Animal Genes : TreeFamTRIM59
HOVERGENQ8IWR1
HOGENOMQ8IWR1
Homologs : HomoloGeneTRIM59
Homology/Alignments : Family Browser (UCSC)TRIM59
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTRIM59 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TRIM59
dbVarTRIM59
ClinVarTRIM59
1000_GenomesTRIM59 
Exome Variant ServerTRIM59
ExAC (Exome Aggregation Consortium)TRIM59 (select the gene name)
Genetic variants : HAPMAP286827
Genomic Variants (DGV)TRIM59 [DGVbeta]
DECIPHER (Syndromes)3:160153291-160167626  ENSG00000213186
CONAN: Copy Number AnalysisTRIM59 
Mutations
ICGC Data PortalTRIM59 
TCGA Data PortalTRIM59 
Broad Tumor PortalTRIM59
OASIS PortalTRIM59 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTRIM59  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDTRIM59
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch TRIM59
DgiDB (Drug Gene Interaction Database)TRIM59
DoCM (Curated mutations)TRIM59 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)TRIM59 (select a term)
intoGenTRIM59
Cancer3DTRIM59(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM616148   
Orphanet
MedgenTRIM59
Genetic Testing Registry TRIM59
NextProtQ8IWR1 [Medical]
TSGene286827
GENETestsTRIM59
Huge Navigator TRIM59 [HugePedia]
snp3D : Map Gene to Disease286827
BioCentury BCIQTRIM59
ClinGenTRIM59
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD286827
Chemical/Pharm GKB GenePA134899610
Clinical trialTRIM59
Miscellaneous
canSAR (ICR)TRIM59 (select the gene name)
Probes
Litterature
PubMed7 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTRIM59
EVEXTRIM59
GoPubMedTRIM59
iHOPTRIM59
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Mar 30 15:23:30 CEST 2017

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