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TRIM59 (tripartite motif containing 59)

Identity

Alias (NCBI)IFT80L
MRF1
RNF104
TRIM57
TSBF1
HGNC (Hugo) TRIM59
HGNC Alias symbTSBF1
Mrf1
RNF104
HGNC Previous nameTRIM57
HGNC Previous nametripartite motif-containing 57
 tripartite motif-containing 59
LocusID (NCBI) 286827
Atlas_Id 42711
Location 3q25.33  [Link to chromosome band 3q25]
Location_base_pair Starts at 160435503 and ends at 160449786 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
TRIM59 (3q25.33) / IFT80 (3q25.33)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)TRIM59   30834
Cards
Entrez_Gene (NCBI)TRIM59    tripartite motif containing 59
AliasesIFT80L; MRF1; RNF104; TRIM57; 
TSBF1
GeneCards (Weizmann)TRIM59
Ensembl hg19 (Hinxton)ENSG00000213186 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000213186 [Gene_View]  ENSG00000213186 [Sequence]  chr3:160435503-160449786 [Contig_View]  TRIM59 [Vega]
ICGC DataPortalENSG00000213186
TCGA cBioPortalTRIM59
AceView (NCBI)TRIM59
Genatlas (Paris)TRIM59
SOURCE (Princeton)TRIM59
Genetics Home Reference (NIH)TRIM59
Genomic and cartography
GoldenPath hg38 (UCSC)TRIM59  -     chr3:160435503-160449786 -  3q25.33   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TRIM59  -     3q25.33   [Description]    (hg19-Feb_2009)
GoldenPathTRIM59 - 3q25.33 [CytoView hg19]  TRIM59 - 3q25.33 [CytoView hg38]
ImmunoBaseENSG00000213186
Genome Data Viewer NCBITRIM59 [Mapview hg19]  
OMIM616148   
Gene and transcription
Genbank (Entrez)AI215011 AK291284 AY159379 BC109259 BC109260
RefSeq transcript (Entrez)NM_173084
Consensus coding sequences : CCDS (NCBI)TRIM59
Gene ExpressionTRIM59 [ NCBI-GEO ]   TRIM59 [ EBI - ARRAY_EXPRESS ]   TRIM59 [ SEEK ]   TRIM59 [ MEM ]
Gene Expression Viewer (FireBrowse)TRIM59 [ Firebrowse - Broad ]
GenevisibleExpression of TRIM59 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)286827
GTEX Portal (Tissue expression)TRIM59
Human Protein AtlasENSG00000213186-TRIM59 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8IWR1   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8IWR1  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8IWR1
PhosPhoSitePlusQ8IWR1
Domaine pattern : Prosite (Expaxy)ZF_BBOX (PS50119)    ZF_RING_1 (PS00518)    ZF_RING_2 (PS50089)   
Domains : Interpro (EBI)Znf-RING_LisH    Znf_B-box    Znf_RING    Znf_RING/FYVE/PHD    Znf_RING_CS   
Domain families : Pfam (Sanger)zf-B_box (PF00643)    zf-RING_UBOX (PF13445)   
Domain families : Pfam (NCBI)pfam00643    pfam13445   
Domain families : Smart (EMBL)RING (SM00184)  
Conserved Domain (NCBI)TRIM59
SuperfamilyQ8IWR1
AlphaFold pdb e-kbQ8IWR1   
Human Protein Atlas [tissue]ENSG00000213186-TRIM59 [tissue]
HPRD15568
Protein Interaction databases
DIP (DOE-UCLA)Q8IWR1
IntAct (EBI)Q8IWR1
BioGRIDTRIM59
STRING (EMBL)TRIM59
ZODIACTRIM59
Ontologies - Pathways
QuickGOQ8IWR1
Ontology : AmiGOprotein binding  endoplasmic reticulum  endoplasmic reticulum membrane  zinc ion binding  integral component of membrane  protein ubiquitination  intraciliary transport particle B  negative regulation of I-kappaB kinase/NF-kappaB signaling  negative regulation of I-kappaB kinase/NF-kappaB signaling  innate immune response  negative regulation of viral entry into host cell  ubiquitin protein ligase activity  
Ontology : EGO-EBIprotein binding  endoplasmic reticulum  endoplasmic reticulum membrane  zinc ion binding  integral component of membrane  protein ubiquitination  intraciliary transport particle B  negative regulation of I-kappaB kinase/NF-kappaB signaling  negative regulation of I-kappaB kinase/NF-kappaB signaling  innate immune response  negative regulation of viral entry into host cell  ubiquitin protein ligase activity  
NDEx NetworkTRIM59
Atlas of Cancer Signalling NetworkTRIM59
Wikipedia pathwaysTRIM59
Orthology - Evolution
OrthoDB286827
GeneTree (enSembl)ENSG00000213186
Phylogenetic Trees/Animal Genes : TreeFamTRIM59
Homologs : HomoloGeneTRIM59
Homology/Alignments : Family Browser (UCSC)TRIM59
Gene fusions - Rearrangements
Fusion : QuiverTRIM59
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTRIM59 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TRIM59
dbVarTRIM59
ClinVarTRIM59
MonarchTRIM59
1000_GenomesTRIM59 
Exome Variant ServerTRIM59
GNOMAD BrowserENSG00000213186
Varsome BrowserTRIM59
ACMGTRIM59 variants
VarityQ8IWR1
Genomic Variants (DGV)TRIM59 [DGVbeta]
DECIPHERTRIM59 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTRIM59 
Mutations
ICGC Data PortalTRIM59 
TCGA Data PortalTRIM59 
Broad Tumor PortalTRIM59
OASIS PortalTRIM59 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTRIM59  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DTRIM59
Mutations and Diseases : HGMDTRIM59
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaTRIM59
DgiDB (Drug Gene Interaction Database)TRIM59
DoCM (Curated mutations)TRIM59
CIViC (Clinical Interpretations of Variants in Cancer)TRIM59
Cancer3DTRIM59
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM616148   
Orphanet
DisGeNETTRIM59
MedgenTRIM59
Genetic Testing Registry TRIM59
NextProtQ8IWR1 [Medical]
GENETestsTRIM59
Target ValidationTRIM59
Huge Navigator TRIM59 [HugePedia]
ClinGenTRIM59
Clinical trials, drugs, therapy
MyCancerGenomeTRIM59
Protein Interactions : CTDTRIM59
Pharm GKB GenePA134899610
PharosQ8IWR1
Clinical trialTRIM59
Miscellaneous
canSAR (ICR)TRIM59
HarmonizomeTRIM59
DataMed IndexTRIM59
Probes
Litterature
PubMed46 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXTRIM59
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 15:36:24 CEST 2021

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