TRIM62 (tripartite motif containing 62)

2009-09-01  

Identity

HGNC
LOCATION
1p35.1
LOCUSID
ALIAS
DEAR1

Other Information

Locus ID:

NCBI: 55223
MIM: 616755
HGNC: 25574
Ensembl: ENSG00000116525

Variants:

dbSNP: 55223
ClinVar: 55223
TCGA: ENSG00000116525
COSMIC: TRIM62

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000116525ENST00000291416Q9BVG3
ENSG00000116525ENST00000543586Q9BVG3

Expression (GTEx)

0
5
10
15
20
25
30

Pathways

PathwaySourceExternal ID
Immune SystemREACTOMER-HSA-168256
Cytokine Signaling in Immune systemREACTOMER-HSA-1280215
Interferon SignalingREACTOMER-HSA-913531
Interferon gamma signalingREACTOMER-HSA-877300

References

Pubmed IDYearTitleCitations
366318762023M2 macrophage-derived exosomal miR-193b-3p promotes progression and glutamine uptake of pancreatic cancer by targeting TRIM62.9
366318762023M2 macrophage-derived exosomal miR-193b-3p promotes progression and glutamine uptake of pancreatic cancer by targeting TRIM62.9
354698512022TRIM62 silencing represses the proliferation and invasion and increases the chemosensitivity of hepatocellular carcinoma cells by affecting the NF-κB pathway.2
354698512022TRIM62 silencing represses the proliferation and invasion and increases the chemosensitivity of hepatocellular carcinoma cells by affecting the NF-κB pathway.2
330930672020USP15 Deubiquitinates CARD9 to Downregulate C-Type Lectin Receptor-Mediated Signaling.5
330930672020USP15 Deubiquitinates CARD9 to Downregulate C-Type Lectin Receptor-Mediated Signaling.5
277931722016Tripartite motif containing 62 is a novel prognostic marker and suppresses tumor metastasis via c-Jun/Slug signaling-mediated epithelial-mesenchymal transition in cervical cancer.18
277931722016Tripartite motif containing 62 is a novel prognostic marker and suppresses tumor metastasis via c-Jun/Slug signaling-mediated epithelial-mesenchymal transition in cervical cancer.18
252489262015Loss of TRIM62 expression is an independent adverse prognostic factor in acute myeloid leukemia.23
264888162015Ubiquitin Ligase TRIM62 Regulates CARD9-Mediated Anti-fungal Immunity and Intestinal Inflammation.62
252489262015Loss of TRIM62 expression is an independent adverse prognostic factor in acute myeloid leukemia.23
264888162015Ubiquitin Ligase TRIM62 Regulates CARD9-Mediated Anti-fungal Immunity and Intestinal Inflammation.62
252612352014DEAR1, a novel tumor suppressor that regulates cell polarity and epithelial plasticity.16
252612352014DEAR1, a novel tumor suppressor that regulates cell polarity and epithelial plasticity.16
234027502013Characterization of TRIM62 as a RING finger E3 ubiquitin ligase and its subcellular localization.11

Citation

Dessen P

TRIM62 (tripartite motif containing 62)

Atlas Genet Cytogenet Oncol Haematol. 2009-09-01

Online version: http://atlasgeneticsoncology.org/gene/51075/trim62