Atlas of Genetics and Cytogenetics in Oncology and Haematology

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TRIM68 (tripartite motif containing 68)

Identity

Alias_namesRNF137
ring finger protein 137
tripartite motif-containing 68
Alias_symbol (synonym)SS-56
FLJ10369
Other aliasGC109
SS56
HGNC (Hugo) TRIM68
LocusID (NCBI) 55128
Atlas_Id 42129
Location 11p15.4  [Link to chromosome band 11p15]
Location_base_pair Starts at 4598672 and ends at 4608259 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)		TRIM68 (11p15.4) / TRIM68 (11p15.4)YEATS2 (3q27.1) / TRIM68 (11p15.4)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)TRIM68   21161
Cards
Entrez_Gene (NCBI)TRIM68  55128  tripartite motif containing 68
AliasesGC109; RNF137; SS-56; SS56
GeneCards (Weizmann)TRIM68
Ensembl hg19 (Hinxton)ENSG00000167333 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000167333 [Gene_View]  chr11:4598672-4608259 [Contig_View]  TRIM68 [Vega]
ICGC DataPortalENSG00000167333
TCGA cBioPortalTRIM68
AceView (NCBI)TRIM68
Genatlas (Paris)TRIM68
WikiGenes55128
SOURCE (Princeton)TRIM68
Genetics Home Reference (NIH)TRIM68
Genomic and cartography
GoldenPath hg38 (UCSC)TRIM68  -     chr11:4598672-4608259 -  11p15.4   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TRIM68  -     11p15.4   [Description]    (hg19-Feb_2009)
EnsemblTRIM68 - 11p15.4 [CytoView hg19]  TRIM68 - 11p15.4 [CytoView hg38]
Mapping of homologs : NCBITRIM68 [Mapview hg19]  TRIM68 [Mapview hg38]
OMIM613184   
Gene and transcription
Genbank (Entrez)AF360739 AF439153 AK001231 AK022923 AK056523
RefSeq transcript (Entrez)NM_001304496 NM_018073
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)TRIM68
Cluster EST : UnigeneHs.738828 [ NCBI ]
CGAP (NCI)Hs.738828
Alternative Splicing GalleryENSG00000167333
Gene ExpressionTRIM68 [ NCBI-GEO ]   TRIM68 [ EBI - ARRAY_EXPRESS ]   TRIM68 [ SEEK ]   TRIM68 [ MEM ]
Gene Expression Viewer (FireBrowse)TRIM68 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)55128
GTEX Portal (Tissue expression)TRIM68
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ6AZZ1   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ6AZZ1  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ6AZZ1
Splice isoforms : SwissVarQ6AZZ1
Catalytic activity : Enzyme2.3.2.27 [ Enzyme-Expasy ]   2.3.2.272.3.2.27 [ IntEnz-EBI ]   2.3.2.27 [ BRENDA ]   2.3.2.27 [ KEGG ]   
PhosPhoSitePlusQ6AZZ1
Domaine pattern : Prosite (Expaxy)B302_SPRY (PS50188)    ZF_BBOX (PS50119)    ZF_RING_1 (PS00518)    ZF_RING_2 (PS50089)   
Domains : Interpro (EBI)B30.2/SPRY    Butyrophylin    ConA-like_dom    PRY    SPRY_dom    Znf_B-box    Znf_RING    Znf_RING/FYVE/PHD    Znf_RING_CS   
Domain families : Pfam (Sanger)PRY (PF13765)    SPRY (PF00622)    zf-B_box (PF00643)   
Domain families : Pfam (NCBI)pfam13765    pfam00622    pfam00643   
Domain families : Smart (EMBL)BBOX (SM00336)  PRY (SM00589)  RING (SM00184)  SPRY (SM00449)  
Conserved Domain (NCBI)TRIM68
DMDM Disease mutations55128
Blocks (Seattle)TRIM68
SuperfamilyQ6AZZ1
Human Protein AtlasENSG00000167333
Peptide AtlasQ6AZZ1
HPRD11507
IPIIPI00292487   IPI01011103   IPI00977425   IPI00976835   IPI00983538   
Protein Interaction databases
DIP (DOE-UCLA)Q6AZZ1
IntAct (EBI)Q6AZZ1
FunCoupENSG00000167333
BioGRIDTRIM68
STRING (EMBL)TRIM68
ZODIACTRIM68
Ontologies - Pathways
QuickGOQ6AZZ1
Ontology : AmiGOubiquitin-protein transferase activity  nucleus  nucleolus  cytoplasm  Golgi apparatus  cytosol  cytosol  zinc ion binding  histone acetyltransferase binding  perinuclear region of cytoplasm  androgen receptor binding  protein autoubiquitination  interferon-gamma-mediated signaling pathway  regulation of androgen receptor signaling pathway  
Ontology : EGO-EBIubiquitin-protein transferase activity  nucleus  nucleolus  cytoplasm  Golgi apparatus  cytosol  cytosol  zinc ion binding  histone acetyltransferase binding  perinuclear region of cytoplasm  androgen receptor binding  protein autoubiquitination  interferon-gamma-mediated signaling pathway  regulation of androgen receptor signaling pathway  
NDEx NetworkTRIM68
Atlas of Cancer Signalling NetworkTRIM68
Wikipedia pathwaysTRIM68
Orthology - Evolution
OrthoDB55128
GeneTree (enSembl)ENSG00000167333
Phylogenetic Trees/Animal Genes : TreeFamTRIM68
HOVERGENQ6AZZ1
HOGENOMQ6AZZ1
Homologs : HomoloGeneTRIM68
Homology/Alignments : Family Browser (UCSC)TRIM68
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTRIM68 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TRIM68
dbVarTRIM68
ClinVarTRIM68
1000_GenomesTRIM68 
Exome Variant ServerTRIM68
ExAC (Exome Aggregation Consortium)TRIM68 (select the gene name)
Genetic variants : HAPMAP55128
Genomic Variants (DGV)TRIM68 [DGVbeta]
DECIPHERTRIM68 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTRIM68 
Mutations
ICGC Data PortalTRIM68 
TCGA Data PortalTRIM68 
Broad Tumor PortalTRIM68
OASIS PortalTRIM68 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTRIM68  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDTRIM68
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch TRIM68
DgiDB (Drug Gene Interaction Database)TRIM68
DoCM (Curated mutations)TRIM68 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)TRIM68 (select a term)
intoGenTRIM68
Cancer3DTRIM68(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM613184   
Orphanet
MedgenTRIM68
Genetic Testing Registry TRIM68
NextProtQ6AZZ1 [Medical]
TSGene55128
GENETestsTRIM68
Target ValidationTRIM68
Huge Navigator TRIM68 [HugePedia]
snp3D : Map Gene to Disease55128
BioCentury BCIQTRIM68
ClinGenTRIM68
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD55128
Chemical/Pharm GKB GenePA134939870
Clinical trialTRIM68
Miscellaneous
canSAR (ICR)TRIM68 (select the gene name)
Probes
Litterature
PubMed20 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTRIM68
EVEXTRIM68
GoPubMedTRIM68
iHOPTRIM68
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Jun 7 13:00:55 CEST 2017
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