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TRIM69 (tripartite motif containing 69)

Identity

Alias_namesRNF36
ring finger protein 36
tripartite motif-containing 69
Alias_symbol (synonym)Trif
TRIMLESS
Other aliasHSD-34
HSD34
HGNC (Hugo) TRIM69
LocusID (NCBI) 140691
Atlas_Id 75180
Location 15q21.1  [Link to chromosome band 15q21]
Location_base_pair Starts at 44736362 and ends at 44767829 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
CREBBP (16p13.3) / TRIM69 (15q21.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

JTD!WIDTH=15%>IPI
Nomenclature
HGNC (Hugo)TRIM69   17857
Cards
Entrez_Gene (NCBI)TRIM69  140691  tripartite motif containing 69
AliasesHSD-34; HSD34; RNF36; Trif
GeneCards (Weizmann)TRIM69
Ensembl hg19 (Hinxton)ENSG00000185880 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000185880 [Gene_View]  chr15:44736362-44767829 [Contig_View]  TRIM69 [Vega]
ICGC DataPortalENSG00000185880
TCGA cBioPortalTRIM69
AceView (NCBI)TRIM69
Genatlas (Paris)TRIM69
WikiGenes140691
SOURCE (Princeton)TRIM69
Genetics Home Reference (NIH)TRIM69
Genomic and cartography
GoldenPath hg38 (UCSC)TRIM69  -     chr15:44736362-44767829 +  15q21.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TRIM69  -     15q21.1   [Description]    (hg19-Feb_2009)
EnsemblTRIM69 - 15q21.1 [CytoView hg19]  TRIM69 - 15q21.1 [CytoView hg38]
Mapping of homologs : NCBITRIM69 [Mapview hg19]  TRIM69 [Mapview hg38]
OMIM616017   
Gene and transcription
Genbank (Entrez)AF302088 AF302089 AK226115 AK292252 AL360161
RefSeq transcript (Entrez)NM_001301144 NM_001301145 NM_001301146 NM_080745 NM_182985
RefSeq genomic (Entrez)NC_000015 NC_018926 NG_033935 NT_187605
Consensus coding sequences : CCDS (NCBI)TRIM69
Cluster EST : UnigeneHs.745248 [ NCBI ]
CGAP (NCI)Hs.745248
Alternative Splicing GalleryENSG00000185880
Gene ExpressionTRIM69 [ NCBI-GEO ]   TRIM69 [ EBI - ARRAY_EXPRESS ]   TRIM69 [ SEEK ]   TRIM69 [ MEM ]
Gene Expression Viewer (FireBrowse)TRIM69 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)140691
GTEX Portal (Tissue expression)TRIM69
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ86WT6   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ86WT6  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ86WT6
Splice isoforms : SwissVarQ86WT6
Catalytic activity : Enzyme2.3.2.27 [ Enzyme-Expasy ]   2.3.2.272.3.2.27 [ IntEnz-EBI ]   2.3.2.27 [ BRENDA ]   2.3.2.27 [ KEGG ]   
PhosPhoSitePlusQ86WT6
Domaine pattern : Prosite (Expaxy)B302_SPRY (PS50188)    ZF_RING_1 (PS00518)    ZF_RING_2 (PS50089)   
Domains : Interpro (EBI)B30.2/SPRY    Butyrophylin    ConA-like_dom    PRY    SPRY_dom    Znf_B-box    Znf_RING    Znf_RING/FYVE/PHD    Znf_RING_CS   
Domain families : Pfam (Sanger)PRY (PF13765)    SPRY (PF00622)   
Domain families : Pfam (NCBI)pfam13765    pfam00622   
Domain families : Smart (EMBL)PRY (SM00589)  RING (SM00184)  SPRY (SM00449)  
Conserved Domain (NCBI)TRIM69
DMDM Disease mutations140691
Blocks (Seattle)TRIM69
PDB (SRS)4NQJ   
PDB (PDBSum)4NQJ   
PDB (IMB)4NQJ   
PDB (RSDB)4NQJ   
Structural Biology KnowledgeBase4NQJ   
SCOP (Structural Classification of Proteins)4NQJ   
CATH (Classification of proteins structures)4NQJ   
SuperfamilyQ86WT6
Human Protein AtlasENSG00000185880
Peptide AtlasQ86WT6
HPRD11518
IPI00929505   IPI00412458   IPI00418445   IPI00791890   
Protein Interaction databases
DIP (DOE-UCLA)Q86WT6
IntAct (EBI)Q86WT6
FunCoupENSG00000185880
BioGRIDTRIM69
STRING (EMBL)TRIM69
ZODIACTRIM69
Ontologies - Pathways
QuickGOQ86WT6
Ontology : AmiGOprotein polyubiquitination  ubiquitin-protein transferase activity  ubiquitin-protein transferase activity  ubiquitin-protein transferase activity  protein binding  nucleus  cytoplasm  cytosol  apoptotic process  zinc ion binding  nuclear speck  
Ontology : EGO-EBIprotein polyubiquitination  ubiquitin-protein transferase activity  ubiquitin-protein transferase activity  ubiquitin-protein transferase activity  protein binding  nucleus  cytoplasm  cytosol  apoptotic process  zinc ion binding  nuclear speck  
NDEx NetworkTRIM69
Atlas of Cancer Signalling NetworkTRIM69
Wikipedia pathwaysTRIM69
Orthology - Evolution
OrthoDB140691
GeneTree (enSembl)ENSG00000185880
Phylogenetic Trees/Animal Genes : TreeFamTRIM69
HOVERGENQ86WT6
HOGENOMQ86WT6
Homologs : HomoloGeneTRIM69
Homology/Alignments : Family Browser (UCSC)TRIM69
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTRIM69 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TRIM69
dbVarTRIM69
ClinVarTRIM69
1000_GenomesTRIM69 
Exome Variant ServerTRIM69
ExAC (Exome Aggregation Consortium)TRIM69 (select the gene name)
Genetic variants : HAPMAP140691
Genomic Variants (DGV)TRIM69 [DGVbeta]
DECIPHERTRIM69 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTRIM69 
Mutations
ICGC Data PortalTRIM69 
TCGA Data PortalTRIM69 
Broad Tumor PortalTRIM69
OASIS PortalTRIM69 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTRIM69  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDTRIM69
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch TRIM69
DgiDB (Drug Gene Interaction Database)TRIM69
DoCM (Curated mutations)TRIM69 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)TRIM69 (select a term)
intoGenTRIM69
Cancer3DTRIM69(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM616017   
Orphanet
MedgenTRIM69
Genetic Testing Registry TRIM69
NextProtQ86WT6 [Medical]
TSGene140691
GENETestsTRIM69
Target ValidationTRIM69
Huge Navigator TRIM69 [HugePedia]
snp3D : Map Gene to Disease140691
BioCentury BCIQTRIM69
ClinGenTRIM69
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD140691
Chemical/Pharm GKB GenePA162407010
Clinical trialTRIM69
Miscellaneous
canSAR (ICR)TRIM69 (select the gene name)
Probes
Litterature
PubMed18 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTRIM69
EVEXTRIM69
GoPubMedTRIM69
iHOPTRIM69
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 18 13:42:36 CEST 2017

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