TRIM71 (tripartite motif containing 71)

2013-04-01  

Identity

HGNC
LOCATION
3p22.3
LOCUSID
ALIAS
HYDCC1,LIN-41,LIN41

Other Information

Locus ID:

NCBI: 131405
MIM: 618570
HGNC: 32669
Ensembl: ENSG00000206557

Variants:

dbSNP: 131405
ClinVar: 131405
TCGA: ENSG00000206557
COSMIC: TRIM71

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000206557ENST00000383763Q2Q1W2

Expression (GTEx)

0
1
2
3
4
5
6
7
8
9
10

Pathways

PathwaySourceExternal ID
MicroRNAs in cancerKEGGhsa05206
MicroRNAs in cancerKEGGko05206
Immune SystemREACTOMER-HSA-168256
Adaptive Immune SystemREACTOMER-HSA-1280218
Class I MHC mediated antigen processing & presentationREACTOMER-HSA-983169
Antigen processing: Ubiquitination & Proteasome degradationREACTOMER-HSA-983168

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
362446482023HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.4
362446482023HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.4
358936762022TRIM7 Restricts Coxsackievirus and Norovirus Infection by Detecting the C-Terminal Glutamine Generated by 3C Protease Processing.3
358936762022TRIM7 Restricts Coxsackievirus and Norovirus Infection by Detecting the C-Terminal Glutamine Generated by 3C Protease Processing.3
328165992020TRIM71 binds to IMP1 and is capable of positive and negative regulation of target RNAs.4
328165992020TRIM71 binds to IMP1 and is capable of positive and negative regulation of target RNAs.4
313714372019The RNA hairpin binder TRIM71 modulates alternative splicing by repressing MBNL1.22
315707062019Ubiquitin ligase TRIM71 suppresses ovarian tumorigenesis by degrading mutant p53.22
317327462019The mRNA repressor TRIM71 cooperates with Nonsense-Mediated Decay factors to destabilize the mRNA of CDKN1A/p21.21
313714372019The RNA hairpin binder TRIM71 modulates alternative splicing by repressing MBNL1.22
315707062019Ubiquitin ligase TRIM71 suppresses ovarian tumorigenesis by degrading mutant p53.22
317327462019The mRNA repressor TRIM71 cooperates with Nonsense-Mediated Decay factors to destabilize the mRNA of CDKN1A/p21.21
278218012016TRIM71 suppresses tumorigenesis via modulation of Lin28B-let-7-HMGA2 signaling.14
278218012016TRIM71 suppresses tumorigenesis via modulation of Lin28B-let-7-HMGA2 signaling.14
265146222015TRIM-NHL proteins in development and disease.50

Citation

Dessen P

TRIM71 (tripartite motif containing 71)

Atlas Genet Cytogenet Oncol Haematol. 2013-04-01

Online version: http://atlasgeneticsoncology.org/gene/53250/trim71