Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

TRIM8 (tripartite motif containing 8)

Identity

Other namesGERP
RNF27
HGNC (Hugo) TRIM8
LocusID (NCBI) 81603
Location 10q24.32
Location_base_pair Starts at 104404252 and ends at 104418076 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)TRIM8   15579
Cards
Entrez_Gene (NCBI)TRIM8  81603  tripartite motif containing 8
GeneCards (Weizmann)TRIM8
Ensembl hg19 (Hinxton)ENSG00000171206 [Gene_View]  chr10:104404252-104418076 [Contig_View]  TRIM8 [Vega]
Ensembl hg38 (Hinxton)ENSG00000171206 [Gene_View]  chr10:104404252-104418076 [Contig_View]  TRIM8 [Vega]
ICGC DataPortalENSG00000171206
cBioPortalTRIM8
AceView (NCBI)TRIM8
Genatlas (Paris)TRIM8
WikiGenes81603
SOURCE (Princeton)TRIM8
Genomic and cartography
GoldenPath hg19 (UCSC)TRIM8  -     chr10:104404252-104418076 +  10q24.32   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)TRIM8  -     10q24.32   [Description]    (hg38-Dec_2013)
EnsemblTRIM8 - 10q24.32 [CytoView hg19]  TRIM8 - 10q24.32 [CytoView hg38]
Mapping of homologs : NCBITRIM8 [Mapview hg19]  TRIM8 [Mapview hg38]
OMIM606125   
Gene and transcription
Genbank (Entrez)AA907931 AF086326 AF220034 AF281046 AL360160
RefSeq transcript (Entrez)NM_030912
RefSeq genomic (Entrez)AC_000142 NC_000010 NC_018921 NT_030059 NW_001838006 NW_004929376
Consensus coding sequences : CCDS (NCBI)TRIM8
Cluster EST : UnigeneHs.336810 [ NCBI ]
CGAP (NCI)Hs.336810
Alternative Splicing : Fast-db (Paris)GSHG0003651
Alternative Splicing GalleryENSG00000171206
Gene ExpressionTRIM8 [ NCBI-GEO ]     TRIM8 [ SEEK ]   TRIM8 [ MEM ]
SOURCE (Princeton)Expression in : [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9BZR9 (Uniprot)
NextProtQ9BZR9  [Medical]
With graphics : InterProQ9BZR9
Splice isoforms : SwissVarQ9BZR9 (Swissvar)
Catalytic activity : Enzyme6.3.2.- [ Enzyme-Expasy ]   6.3.2.-6.3.2.- [ IntEnz-EBI ]   6.3.2.- [ BRENDA ]   6.3.2.- [ KEGG ]   
Domaine pattern : Prosite (Expaxy)ZF_RING_1 (PS00518)    ZF_RING_2 (PS50089)   
Domains : Interpro (EBI)Znf_RING    Znf_RING/FYVE/PHD    Znf_RING_CS   
Related proteins : CluSTrQ9BZR9
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Domain families : Smart (EMBL)RING (SM00184)  
DMDM Disease mutations81603
Blocks (Seattle)Q9BZR9
Human Protein AtlasENSG00000171206
Peptide AtlasQ9BZR9
HPRD06934
IPIIPI00289207   
Protein Interaction databases
DIP (DOE-UCLA)Q9BZR9
IntAct (EBI)Q9BZR9
FunCoupENSG00000171206
BioGRIDTRIM8
IntegromeDBTRIM8
STRING (EMBL)TRIM8
Ontologies - Pathways
QuickGOQ9BZR9
Ontology : AmiGOnucleus  nucleolus  cytoplasm  zinc ion binding  protein ubiquitination  PML body  ligase activity  identical protein binding  protein homodimerization activity  positive regulation of I-kappaB kinase/NF-kappaB signaling  intracellular membrane-bounded organelle  innate immune response  positive regulation of sequence-specific DNA binding transcription factor activity  positive regulation of NF-kappaB transcription factor activity  negative regulation of viral release from host cell  
Ontology : EGO-EBInucleus  nucleolus  cytoplasm  zinc ion binding  protein ubiquitination  PML body  ligase activity  identical protein binding  protein homodimerization activity  positive regulation of I-kappaB kinase/NF-kappaB signaling  intracellular membrane-bounded organelle  innate immune response  positive regulation of sequence-specific DNA binding transcription factor activity  positive regulation of NF-kappaB transcription factor activity  negative regulation of viral release from host cell  
Protein Interaction DatabaseTRIM8
DoCM (Curated mutations)TRIM8
Wikipedia pathwaysTRIM8
Gene fusion - rearrangements
Polymorphisms : SNP, variants
NCBI Variation ViewerTRIM8 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TRIM8
dbVarTRIM8
ClinVarTRIM8
1000_GenomesTRIM8 
Exome Variant ServerTRIM8
SNP (GeneSNP Utah)TRIM8
SNP : HGBaseTRIM8
Genetic variants : HAPMAPTRIM8
Genomic VariantsTRIM8  TRIM8 [DGVbeta]
Mutations
ICGC Data PortalENSG00000171206 
Somatic Mutations in Cancer : COSMICTRIM8 
CONAN: Copy Number AnalysisTRIM8 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] 
Diseases
DECIPHER (Syndromes)10:104404252-104418076
Mutations and Diseases : HGMDTRIM8
OMIM606125   
MedgenTRIM8
NextProtQ9BZR9 [Medical]
GENETestsTRIM8
Disease Genetic AssociationTRIM8
Huge Navigator TRIM8 [HugePedia]  TRIM8 [HugeCancerGEM]
snp3D : Map Gene to Disease81603
DGIdb (Drug Gene Interaction db)TRIM8
General knowledge
Homologs : HomoloGeneTRIM8
Homology/Alignments : Family Browser (UCSC)TRIM8
Phylogenetic Trees/Animal Genes : TreeFamTRIM8
Chemical/Protein Interactions : CTD81603
Chemical/Pharm GKB GenePA37983
Clinical trialTRIM8
Cancer Resource (Charite)ENSG00000171206
Other databases
Probes
Litterature
PubMed23 Pubmed reference(s) in Entrez
CoreMineTRIM8
GoPubMedTRIM8
iHOPTRIM8
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated12-2014Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Sun Dec 21 02:05:27 CET 2014

Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.