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TRIM8 (tripartite motif containing 8)

Identity

Other namesGERP
RNF27
HGNC (Hugo) TRIM8
LocusID (NCBI) 81603
Location 10q24.32
Location_base_pair Starts at 104404252 and ends at 104418076 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)TRIM8   15579
Cards
Entrez_Gene (NCBI)TRIM8  81603  tripartite motif containing 8
GeneCards (Weizmann)TRIM8
Ensembl (Hinxton)ENSG00000171206 [Gene_View]  chr10:104404252-104418076 [Contig_View]  TRIM8 [Vega]
ICGC DataPortalENSG00000171206
AceView (NCBI)TRIM8
Genatlas (Paris)TRIM8
WikiGenes81603
SOURCE (Princeton)NM_030912
Genomic and cartography
GoldenPath (UCSC)TRIM8  -  10q24.32   chr10:104404252-104418076 +  10q24.32   [Description]    (hg19-Feb_2009)
EnsemblTRIM8 - 10q24.32 [CytoView]
Mapping of homologs : NCBITRIM8 [Mapview]
OMIM606125   
Gene and transcription
Genbank (Entrez)AA907931 AF086326 AF220034 AF281046 AL360160
RefSeq transcript (Entrez)NM_030912
RefSeq genomic (Entrez)AC_000142 NC_000010 NC_018921 NT_030059 NW_001838006 NW_004929376
Consensus coding sequences : CCDS (NCBI)TRIM8
Cluster EST : UnigeneHs.336810 [ NCBI ]
CGAP (NCI)Hs.336810
Alternative Splicing : Fast-db (Paris)GSHG0003651
Alternative Splicing GalleryENSG00000171206
Gene ExpressionTRIM8 [ NCBI-GEO ]     TRIM8 [ SEEK ]   TRIM8 [ MEM ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9BZR9 (Uniprot)
NextProtQ9BZR9  [Medical]
With graphics : InterProQ9BZR9
Splice isoforms : SwissVarQ9BZR9 (Swissvar)
Catalytic activity : Enzyme6.3.2.- [ Enzyme-Expasy ]   6.3.2.-6.3.2.- [ IntEnz-EBI ]   6.3.2.- [ BRENDA ]   6.3.2.- [ KEGG ]   
Domaine pattern : Prosite (Expaxy)ZF_RING_1 (PS00518)    ZF_RING_2 (PS50089)   
Domains : Interpro (EBI)Znf_RING    Znf_RING/FYVE/PHD    Znf_RING_CS   
Related proteins : CluSTrQ9BZR9
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Domain families : Smart (EMBL)RING (SM00184)  
DMDM Disease mutations81603
Blocks (Seattle)Q9BZR9
Human Protein AtlasENSG00000171206
Peptide AtlasQ9BZR9
HPRD06934
IPIIPI00289207   
Protein Interaction databases
DIP (DOE-UCLA)Q9BZR9
IntAct (EBI)Q9BZR9
FunCoupENSG00000171206
BioGRIDTRIM8
InParanoidQ9BZR9
Interologous Interaction database Q9BZR9
IntegromeDBTRIM8
STRING (EMBL)TRIM8
Ontologies - Pathways
Ontology : AmiGOnucleus  nucleolus  cytoplasm  zinc ion binding  protein ubiquitination  PML body  ligase activity  identical protein binding  protein homodimerization activity  positive regulation of I-kappaB kinase/NF-kappaB signaling  intracellular membrane-bounded organelle  innate immune response  positive regulation of sequence-specific DNA binding transcription factor activity  positive regulation of NF-kappaB transcription factor activity  negative regulation of viral release from host cell  
Ontology : EGO-EBInucleus  nucleolus  cytoplasm  zinc ion binding  protein ubiquitination  PML body  ligase activity  identical protein binding  protein homodimerization activity  positive regulation of I-kappaB kinase/NF-kappaB signaling  intracellular membrane-bounded organelle  innate immune response  positive regulation of sequence-specific DNA binding transcription factor activity  positive regulation of NF-kappaB transcription factor activity  negative regulation of viral release from host cell  
Protein Interaction DatabaseTRIM8
Wikipedia pathwaysTRIM8
Gene fusion - rearrangments
Polymorphisms : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)TRIM8
SNP (GeneSNP Utah)TRIM8
SNP : HGBaseTRIM8
Genetic variants : HAPMAPTRIM8
1000_GenomesTRIM8 
ICGC programENSG00000171206 
CONAN: Copy Number AnalysisTRIM8 
Somatic Mutations in Cancer : COSMICTRIM8 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
Mutations and Diseases : HGMDTRIM8
OMIM606125   
MedgenTRIM8
GENETestsTRIM8
Disease Genetic AssociationTRIM8
Huge Navigator TRIM8 [HugePedia]  TRIM8 [HugeCancerGEM]
Genomic VariantsTRIM8  TRIM8 [DGVbeta]
Exome VariantTRIM8
dbVarTRIM8
ClinVarTRIM8
snp3D : Map Gene to Disease81603
General knowledge
Homologs : HomoloGeneTRIM8
Homology/Alignments : Family Browser (UCSC)TRIM8
Phylogenetic Trees/Animal Genes : TreeFamTRIM8
Chemical/Protein Interactions : CTD81603
Chemical/Pharm GKB GenePA37983
Clinical trialTRIM8
Cancer Resource (Charite)ENSG00000171206
Other databases
Probes
Litterature
PubMed23 Pubmed reference(s) in Entrez
CoreMineTRIM8
iHOPTRIM8
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated12-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Oct 13 13:23:30 CEST 2014

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