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TRIOBP (TRIO and F-actin binding protein)

Identity

Alias_namesDFNB28
Alias_symbol (synonym)HRIHFB2122
KIAA1662
Tara
TAP68
Other aliasTARA
dJ37E16.4
HGNC (Hugo) TRIOBP
LocusID (NCBI) 11078
Atlas_Id 55136
Location 22q13.1  [Link to chromosome band 22q13]
Location_base_pair Starts at 37696988 and ends at 37776556 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
AGAP1 (2q37.2) / TRIOBP (22q13.1)GGA1 (22q13.1) / TRIOBP (22q13.1)SH2B3 (12q24.12) / TRIOBP (22q13.1)
SIK3 (11q23.3) / TRIOBP (22q13.1)SYNGR2 (17q25.3) / TRIOBP (22q13.1)SYNPO (5q33.1) / TRIOBP (22q13.1)
TRIOBP (22q13.1) / LGALS1 (22q13.1)TRIOBP (22q13.1) / NDE1 (16p13.11)TRIOBP (22q13.1) / SLCO3A1 (15q26.1)
TRIOBP (22q13.1) / UNC13C (15q21.3)TRIOBP 22q13.1 / UNC13C 15q21.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)TRIOBP   17009
Cards
Entrez_Gene (NCBI)TRIOBP  11078  TRIO and F-actin binding protein
AliasesDFNB28; HRIHFB2122; TAP68; TARA; 
dJ37E16.4
GeneCards (Weizmann)TRIOBP
Ensembl hg19 (Hinxton)ENSG00000100106 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000100106 [Gene_View]  chr22:37696988-37776556 [Contig_View]  TRIOBP [Vega]
ICGC DataPortalENSG00000100106
TCGA cBioPortalTRIOBP
AceView (NCBI)TRIOBP
Genatlas (Paris)TRIOBP
WikiGenes11078
SOURCE (Princeton)TRIOBP
Genetics Home Reference (NIH)TRIOBP
Genomic and cartography
GoldenPath hg38 (UCSC)TRIOBP  -     chr22:37696988-37776556 +  22q13.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TRIOBP  -     22q13.1   [Description]    (hg19-Feb_2009)
EnsemblTRIOBP - 22q13.1 [CytoView hg19]  TRIOBP - 22q13.1 [CytoView hg38]
Mapping of homologs : NCBITRIOBP [Mapview hg19]  TRIOBP [Mapview hg38]
OMIM609761   609823   
Gene and transcription
Genbank (Entrez)AB015343 AF281030 AK096634 AL713698 AM392748
RefSeq transcript (Entrez)NM_001039141 NM_007032 NM_138632
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)TRIOBP
Cluster EST : UnigeneHs.533030 [ NCBI ]
CGAP (NCI)Hs.533030
Alternative Splicing GalleryENSG00000100106
Gene ExpressionTRIOBP [ NCBI-GEO ]   TRIOBP [ EBI - ARRAY_EXPRESS ]   TRIOBP [ SEEK ]   TRIOBP [ MEM ]
Gene Expression Viewer (FireBrowse)TRIOBP [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)11078
GTEX Portal (Tissue expression)TRIOBP
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9H2D6   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9H2D6  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9H2D6
Splice isoforms : SwissVarQ9H2D6
PhosPhoSitePlusQ9H2D6
Domaine pattern : Prosite (Expaxy)PH_DOMAIN (PS50003)   
Domains : Interpro (EBI)PH_dom-like    PH_domain    Tara   
Domain families : Pfam (Sanger)PH (PF00169)   
Domain families : Pfam (NCBI)pfam00169   
Domain families : Smart (EMBL)PH (SM00233)  
Conserved Domain (NCBI)TRIOBP
DMDM Disease mutations11078
Blocks (Seattle)TRIOBP
SuperfamilyQ9H2D6
Human Protein AtlasENSG00000100106
Peptide AtlasQ9H2D6
HPRD11028
IPIIPI00413160   IPI00736522   IPI00741684   IPI00878035   IPI00878567   IPI00952918   IPI00382909   IPI00879297   IPI00332510   IPI00148768   IPI00880004   IPI00878205   IPI00877699   
Protein Interaction databases
DIP (DOE-UCLA)Q9H2D6
IntAct (EBI)Q9H2D6
FunCoupENSG00000100106
BioGRIDTRIOBP
STRING (EMBL)TRIOBP
ZODIACTRIOBP
Ontologies - Pathways
QuickGOQ9H2D6
Ontology : AmiGOnucleus  cytoplasm  microtubule organizing center  focal adhesion  cell cycle  actin cytoskeleton  actin cytoskeleton  GTP-Rho binding  actin modification  midbody  ubiquitin protein ligase binding  myosin II binding  actin filament binding  barbed-end actin filament capping  cell division  positive regulation of substrate adhesion-dependent cell spreading  
Ontology : EGO-EBInucleus  cytoplasm  microtubule organizing center  focal adhesion  cell cycle  actin cytoskeleton  actin cytoskeleton  GTP-Rho binding  actin modification  midbody  ubiquitin protein ligase binding  myosin II binding  actin filament binding  barbed-end actin filament capping  cell division  positive regulation of substrate adhesion-dependent cell spreading  
NDEx NetworkTRIOBP
Atlas of Cancer Signalling NetworkTRIOBP
Wikipedia pathwaysTRIOBP
Orthology - Evolution
OrthoDB11078
GeneTree (enSembl)ENSG00000100106
Phylogenetic Trees/Animal Genes : TreeFamTRIOBP
HOVERGENQ9H2D6
HOGENOMQ9H2D6
Homologs : HomoloGeneTRIOBP
Homology/Alignments : Family Browser (UCSC)TRIOBP
Gene fusions - Rearrangements
Fusion : MitelmanGGA1/TRIOBP [22q13.1/22q13.1]  [t(22;22)(q13;q13)]  
Fusion : MitelmanTRIOBP/UNC13C [22q13.1/15q21.3]  [t(15;22)(q21;q13)]  
Fusion: TCGATRIOBP 22q13.1 UNC13C 15q21.3 LUAD
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTRIOBP [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TRIOBP
dbVarTRIOBP
ClinVarTRIOBP
1000_GenomesTRIOBP 
Exome Variant ServerTRIOBP
ExAC (Exome Aggregation Consortium)TRIOBP (select the gene name)
Genetic variants : HAPMAP11078
Genomic Variants (DGV)TRIOBP [DGVbeta]
DECIPHERTRIOBP [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTRIOBP 
Mutations
ICGC Data PortalTRIOBP 
TCGA Data PortalTRIOBP 
Broad Tumor PortalTRIOBP
OASIS PortalTRIOBP [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTRIOBP  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDTRIOBP
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)MSeqDR-LSDB Mitochondrial Disease Locus Specific Database
BioMutasearch TRIOBP
DgiDB (Drug Gene Interaction Database)TRIOBP
DoCM (Curated mutations)TRIOBP (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)TRIOBP (select a term)
intoGenTRIOBP
Cancer3DTRIOBP(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM609761    609823   
Orphanet12047   
MedgenTRIOBP
Genetic Testing Registry TRIOBP
NextProtQ9H2D6 [Medical]
TSGene11078
GENETestsTRIOBP
Huge Navigator TRIOBP [HugePedia]
snp3D : Map Gene to Disease11078
BioCentury BCIQTRIOBP
ClinGenTRIOBP
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD11078
Chemical/Pharm GKB GenePA142670699
Clinical trialTRIOBP
Miscellaneous
canSAR (ICR)TRIOBP (select the gene name)
Probes
Litterature
PubMed38 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTRIOBP
EVEXTRIOBP
GoPubMedTRIOBP
iHOPTRIOBP
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Fri May 19 12:42:19 CEST 2017

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