TRIP13 (thyroid hormone receptor interactor 13)

2009-11-01  

Identity

HGNC
LOCATION
5p15.33
LOCUSID
ALIAS
16E1BP,MVA3,OOMD9

Other Information

Locus ID:

NCBI: 9319
MIM: 604507
HGNC: 12307
Ensembl: ENSG00000071539

Variants:

dbSNP: 9319
ClinVar: 9319
TCGA: ENSG00000071539
COSMIC: TRIP13

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000071539ENST00000166345Q15645
ENSG00000071539ENST00000513435H0YAL2

Expression (GTEx)

0
10
20
30
40
50
60

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
380399232024Targeting of oncogenic AAA-ATPase TRIP13 reduces progression of pancreatic ductal adenocarcinoma.0
384924252024High expression of TRIP13 is associated with tumor progression in H. pylori infection induced gastric cancer.0
380399232024Targeting of oncogenic AAA-ATPase TRIP13 reduces progression of pancreatic ductal adenocarcinoma.0
384924252024High expression of TRIP13 is associated with tumor progression in H. pylori infection induced gastric cancer.0
368967652023TRIP13 overexpression promotes gefitinib resistance in non‑small cell lung cancer via regulating autophagy and phosphorylation of the EGFR signaling pathway.5
371570152023Aberrant activation of TRIP13-EZH2 signaling axis promotes stemness and therapy resistance in multiple myeloma.1
373409652023Novel mutations in TRIP13 lead to female infertility with oocyte maturation arrest.0
368967652023TRIP13 overexpression promotes gefitinib resistance in non‑small cell lung cancer via regulating autophagy and phosphorylation of the EGFR signaling pathway.5
371570152023Aberrant activation of TRIP13-EZH2 signaling axis promotes stemness and therapy resistance in multiple myeloma.1
373409652023Novel mutations in TRIP13 lead to female infertility with oocyte maturation arrest.0
350322582022TRIP13 knockdown inhibits the proliferation, migration, invasion, and promotes apoptosis by suppressing PI3K/AKT signaling pathway in U2OS cells.4
353229162022Evaluation of the TRIP13 level in breast cancer and insights into potential molecular pathways.8
353625482022MiR-129-5p/TRIP13 affects malignant phenotypes of colorectal cancer cells.3
356011502022TRIP13 Induces Nedaplatin Resistance in Esophageal Squamous Cell Carcinoma by Enhancing Repair of DNA Damage and Inhibiting Apoptosis.2
359727312022Combined TRIP13 and Aurora Kinase Inhibition Induces Apoptosis in Human Papillomavirus-Driven Cancers.6

Citation

Dessen P

TRIP13 (thyroid hormone receptor interactor 13)

Atlas Genet Cytogenet Oncol Haematol. 2009-11-01

Online version: http://atlasgeneticsoncology.org/gene/51188/trip13