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TRIT1 (tRNA isopentenyltransferase 1)

Identity

Alias (NCBI)COXPD35
GRO1
IPPT
IPT
IPTase
MOD5
hGRO1
HGNC (Hugo) TRIT1
HGNC Alias symbFLJ20061
IPT
HGNC Alias nameIPP transferase
 tRNA dimethylallyltransferase
LocusID (NCBI) 54802
Atlas_Id 53605
Location 1p34.2  [Link to chromosome band 1p34]
Location_base_pair Starts at 39838110 and ends at 39883504 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
COL1A1 (17q21.33) / TRIT1 (1p34.2)RLF (1p34.2) / TRIT1 (1p34.2)TRIT1 (1p34.2) / EP400 (12q24.33)
TRIT1 (1p34.2) / MYCL (1p34.2)TRIT1 (1p34.2) / PPIE (1p34.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)TRIT1   20286
Cards
Entrez_Gene (NCBI)TRIT1    tRNA isopentenyltransferase 1
AliasesCOXPD35; GRO1; IPPT; IPT; 
IPTase; MOD5; hGRO1
GeneCards (Weizmann)TRIT1
Ensembl hg19 (Hinxton)ENSG00000043514 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000043514 [Gene_View]  ENSG00000043514 [Sequence]  chr1:39838110-39883504 [Contig_View]  TRIT1 [Vega]
ICGC DataPortalENSG00000043514
TCGA cBioPortalTRIT1
AceView (NCBI)TRIT1
Genatlas (Paris)TRIT1
SOURCE (Princeton)TRIT1
Genetics Home Reference (NIH)TRIT1
Genomic and cartography
GoldenPath hg38 (UCSC)TRIT1  -     chr1:39838110-39883504 -  1p34.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TRIT1  -     1p34.2   [Description]    (hg19-Feb_2009)
GoldenPathTRIT1 - 1p34.2 [CytoView hg19]  TRIT1 - 1p34.2 [CytoView hg38]
ImmunoBaseENSG00000043514
Genome Data Viewer NCBITRIT1 [Mapview hg19]  
OMIM617840   617873   
Gene and transcription
Genbank (Entrez)AF074918 AK000068 AK074222 AK223478 AK296453
RefSeq transcript (Entrez)NM_001312691 NM_001312692 NM_017646
Consensus coding sequences : CCDS (NCBI)TRIT1
Gene ExpressionTRIT1 [ NCBI-GEO ]   TRIT1 [ EBI - ARRAY_EXPRESS ]   TRIT1 [ SEEK ]   TRIT1 [ MEM ]
Gene Expression Viewer (FireBrowse)TRIT1 [ Firebrowse - Broad ]
GenevisibleExpression of TRIT1 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)54802
GTEX Portal (Tissue expression)TRIT1
Human Protein AtlasENSG00000043514-TRIT1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9H3H1   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9H3H1  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9H3H1
PhosPhoSitePlusQ9H3H1
Domains : Interpro (EBI)Dimethylallyltransferase    IPP_transferase_euk    IPT    Matrin/U1-like-C_Znf_C2H2    P-loop_NTPase    Znf_C2H2_jaz    Znf_C2H2_sf   
Domain families : Pfam (Sanger)zf-C2H2_jaz (PF12171)   
Domain families : Pfam (NCBI)pfam12171   
Domain families : Smart (EMBL)ZnF_U1 (SM00451)  
Conserved Domain (NCBI)TRIT1
SuperfamilyQ9H3H1
AlphaFold pdb e-kbQ9H3H1   
Human Protein Atlas [tissue]ENSG00000043514-TRIT1 [tissue]
HPRD18226
Protein Interaction databases
DIP (DOE-UCLA)Q9H3H1
IntAct (EBI)Q9H3H1
BioGRIDTRIT1
STRING (EMBL)TRIT1
ZODIACTRIT1
Ontologies - Pathways
QuickGOQ9H3H1
Ontology : AmiGOnucleic acid binding  ATP binding  mitochondrion  mitochondrion  mitochondrial matrix  tRNA modification  zinc ion binding  tRNA dimethylallyltransferase activity  tRNA dimethylallyltransferase activity  tRNA dimethylallyltransferase activity  mitochondrial tRNA modification  
Ontology : EGO-EBInucleic acid binding  ATP binding  mitochondrion  mitochondrion  mitochondrial matrix  tRNA modification  zinc ion binding  tRNA dimethylallyltransferase activity  tRNA dimethylallyltransferase activity  tRNA dimethylallyltransferase activity  mitochondrial tRNA modification  
NDEx NetworkTRIT1
Atlas of Cancer Signalling NetworkTRIT1
Wikipedia pathwaysTRIT1
Orthology - Evolution
OrthoDB54802
GeneTree (enSembl)ENSG00000043514
Phylogenetic Trees/Animal Genes : TreeFamTRIT1
Homologs : HomoloGeneTRIT1
Homology/Alignments : Family Browser (UCSC)TRIT1
Gene fusions - Rearrangements
Fusion : MitelmanTRIT1/EP400 [1p34.2/12q24.33]  
Fusion : QuiverTRIT1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTRIT1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TRIT1
dbVarTRIT1
ClinVarTRIT1
MonarchTRIT1
1000_GenomesTRIT1 
Exome Variant ServerTRIT1
GNOMAD BrowserENSG00000043514
Varsome BrowserTRIT1
ACMGTRIT1 variants
VarityQ9H3H1
Genomic Variants (DGV)TRIT1 [DGVbeta]
DECIPHERTRIT1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTRIT1 
Mutations
ICGC Data PortalTRIT1 
TCGA Data PortalTRIT1 
Broad Tumor PortalTRIT1
OASIS PortalTRIT1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTRIT1  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DTRIT1
Mutations and Diseases : HGMDTRIT1
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaTRIT1
DgiDB (Drug Gene Interaction Database)TRIT1
DoCM (Curated mutations)TRIT1
CIViC (Clinical Interpretations of Variants in Cancer)TRIT1
Cancer3DTRIT1
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM617840    617873   
Orphanet
DisGeNETTRIT1
MedgenTRIT1
Genetic Testing Registry TRIT1
NextProtQ9H3H1 [Medical]
GENETestsTRIT1
Target ValidationTRIT1
Huge Navigator TRIT1 [HugePedia]
ClinGenTRIT1
Clinical trials, drugs, therapy
MyCancerGenomeTRIT1
Protein Interactions : CTDTRIT1
Pharm GKB GenePA134943037
PharosQ9H3H1
Clinical trialTRIT1
Miscellaneous
canSAR (ICR)TRIT1
HarmonizomeTRIT1
DataMed IndexTRIT1
Probes
Litterature
PubMed26 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXTRIT1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 15:36:27 CEST 2021

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