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TRMT10A (tRNA methyltransferase 10A)

Identity

Alias_namesRG9MTD2
RNA (guanine-9-) methyltransferase domain containing 2
tRNA methyltransferase 10 homolog A (S. cerevisiae)
Alias_symbol (synonym)MGC27034
TRM10
Other aliasHEL-S-88
MSSGM
MSSGM1
HGNC (Hugo) TRMT10A
LocusID (NCBI) 93587
Atlas_Id 42095
Location 4q23  [Link to chromosome band 4q23]
Location_base_pair Starts at 99546707 and ends at 99564057 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)TRMT10A   28403
Cards
Entrez_Gene (NCBI)TRMT10A  93587  tRNA methyltransferase 10A
AliasesHEL-S-88; MSSGM; MSSGM1; RG9MTD2; 
TRM10
GeneCards (Weizmann)TRMT10A
Ensembl hg19 (Hinxton)ENSG00000145331 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000145331 [Gene_View]  chr4:99546707-99564057 [Contig_View]  TRMT10A [Vega]
ICGC DataPortalENSG00000145331
TCGA cBioPortalTRMT10A
AceView (NCBI)TRMT10A
Genatlas (Paris)TRMT10A
WikiGenes93587
SOURCE (Princeton)TRMT10A
Genetics Home Reference (NIH)TRMT10A
Genomic and cartography
GoldenPath hg38 (UCSC)TRMT10A  -     chr4:99546707-99564057 -  4q23   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TRMT10A  -     4q23   [Description]    (hg19-Feb_2009)
EnsemblTRMT10A - 4q23 [CytoView hg19]  TRMT10A - 4q23 [CytoView hg38]
Mapping of homologs : NCBITRMT10A [Mapview hg19]  TRMT10A [Mapview hg38]
OMIM616013   616033   
Gene and transcription
Genbank (Entrez)AF106046 AK000332 AK313548 AW242551 BC028373
RefSeq transcript (Entrez)NM_001134665 NM_001134666 NM_152292
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)TRMT10A
Cluster EST : UnigeneHs.380412 [ NCBI ]
CGAP (NCI)Hs.380412
Alternative Splicing GalleryENSG00000145331
Gene ExpressionTRMT10A [ NCBI-GEO ]   TRMT10A [ EBI - ARRAY_EXPRESS ]   TRMT10A [ SEEK ]   TRMT10A [ MEM ]
Gene Expression Viewer (FireBrowse)TRMT10A [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)93587
GTEX Portal (Tissue expression)TRMT10A
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8TBZ6   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8TBZ6  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8TBZ6
Splice isoforms : SwissVarQ8TBZ6
Catalytic activity : Enzyme2.1.1.- [ Enzyme-Expasy ]   2.1.1.-2.1.1.- [ IntEnz-EBI ]   2.1.1.- [ BRENDA ]   2.1.1.- [ KEGG ]   
PhosPhoSitePlusQ8TBZ6
Domaine pattern : Prosite (Expaxy)SAM_MT_TRM10 (PS51675)   
Domains : Interpro (EBI)MT_TRM10-typ    tRNA_m1G_MeTrfase_euk    tRNA_MeTfrase_TRM10    tRNA_MeTrfase_TRMD/TRM10   
Domain families : Pfam (Sanger)tRNA_m1G_MT (PF01746)   
Domain families : Pfam (NCBI)pfam01746   
Conserved Domain (NCBI)TRMT10A
DMDM Disease mutations93587
Blocks (Seattle)TRMT10A
PDB (SRS)4FMW   
PDB (PDBSum)4FMW   
PDB (IMB)4FMW   
PDB (RSDB)4FMW   
Structural Biology KnowledgeBase4FMW   
SCOP (Structural Classification of Proteins)4FMW   
CATH (Classification of proteins structures)4FMW   
SuperfamilyQ8TBZ6
Human Protein AtlasENSG00000145331
Peptide AtlasQ8TBZ6
HPRD15241
IPIIPI00152325   IPI00965364   IPI00966145   
Protein Interaction databases
DIP (DOE-UCLA)Q8TBZ6
IntAct (EBI)Q8TBZ6
FunCoupENSG00000145331
BioGRIDTRMT10A
STRING (EMBL)TRMT10A
ZODIACTRMT10A
Ontologies - Pathways
QuickGOQ8TBZ6
Ontology : AmiGOtRNA binding  RNA binding  nucleus  nucleoplasm  nucleolus  cytosol  tRNA (guanine-N1-)-methyltransferase activity  actin cytoskeleton  tRNA methylation  extracellular exosome  
Ontology : EGO-EBItRNA binding  RNA binding  nucleus  nucleoplasm  nucleolus  cytosol  tRNA (guanine-N1-)-methyltransferase activity  actin cytoskeleton  tRNA methylation  extracellular exosome  
NDEx NetworkTRMT10A
Atlas of Cancer Signalling NetworkTRMT10A
Wikipedia pathwaysTRMT10A
Orthology - Evolution
OrthoDB93587
GeneTree (enSembl)ENSG00000145331
Phylogenetic Trees/Animal Genes : TreeFamTRMT10A
HOVERGENQ8TBZ6
HOGENOMQ8TBZ6
Homologs : HomoloGeneTRMT10A
Homology/Alignments : Family Browser (UCSC)TRMT10A
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTRMT10A [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TRMT10A
dbVarTRMT10A
ClinVarTRMT10A
1000_GenomesTRMT10A 
Exome Variant ServerTRMT10A
ExAC (Exome Aggregation Consortium)TRMT10A (select the gene name)
Genetic variants : HAPMAP93587
Genomic Variants (DGV)TRMT10A [DGVbeta]
DECIPHERTRMT10A [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTRMT10A 
Mutations
ICGC Data PortalTRMT10A 
TCGA Data PortalTRMT10A 
Broad Tumor PortalTRMT10A
OASIS PortalTRMT10A [ Somatic mutations - Copy number]
Mutations and Diseases : HGMDTRMT10A
BioMutasearch TRMT10A
DgiDB (Drug Gene Interaction Database)TRMT10A
DoCM (Curated mutations)TRMT10A (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)TRMT10A (select a term)
intoGenTRMT10A
Cancer3DTRMT10A(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM616013    616033   
Orphanet22619   
MedgenTRMT10A
Genetic Testing Registry TRMT10A
NextProtQ8TBZ6 [Medical]
TSGene93587
GENETestsTRMT10A
Target ValidationTRMT10A
Huge Navigator TRMT10A [HugePedia]
snp3D : Map Gene to Disease93587
BioCentury BCIQTRMT10A
ClinGenTRMT10A
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD93587
Chemical/Pharm GKB GenePA134979919
Clinical trialTRMT10A
Miscellaneous
canSAR (ICR)TRMT10A (select the gene name)
Probes
Litterature
PubMed10 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTRMT10A
EVEXTRMT10A
GoPubMedTRMT10A
iHOPTRMT10A
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 25 19:36:25 CEST 2017

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