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TRMT10A (tRNA methyltransferase 10A)

Identity

Alias (NCBI)HEL-S-88
MSSGM
MSSGM1
RG9MTD2
TRM10
HGNC (Hugo) TRMT10A
HGNC Alias symbMGC27034
TRM10
HGNC Previous nameRG9MTD2
HGNC Previous nameRNA (guanine-9-) methyltransferase domain containing 2
 tRNA methyltransferase 10 homolog A (S. cerevisiae)
LocusID (NCBI) 93587
Atlas_Id 42095
Location 4q23  [Link to chromosome band 4q23]
Location_base_pair Starts at 99546711 and ends at 99563723 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)TRMT10A   28403
Cards
Entrez_Gene (NCBI)TRMT10A    tRNA methyltransferase 10A
AliasesHEL-S-88; MSSGM; MSSGM1; RG9MTD2; 
TRM10
GeneCards (Weizmann)TRMT10A
Ensembl hg19 (Hinxton)ENSG00000145331 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000145331 [Gene_View]  ENSG00000145331 [Sequence]  chr4:99546711-99563723 [Contig_View]  TRMT10A [Vega]
ICGC DataPortalENSG00000145331
TCGA cBioPortalTRMT10A
AceView (NCBI)TRMT10A
Genatlas (Paris)TRMT10A
SOURCE (Princeton)TRMT10A
Genetics Home Reference (NIH)TRMT10A
Genomic and cartography
GoldenPath hg38 (UCSC)TRMT10A  -     chr4:99546711-99563723 -  4q23   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TRMT10A  -     4q23   [Description]    (hg19-Feb_2009)
GoldenPathTRMT10A - 4q23 [CytoView hg19]  TRMT10A - 4q23 [CytoView hg38]
ImmunoBaseENSG00000145331
Genome Data Viewer NCBITRMT10A [Mapview hg19]  
OMIM616013   616033   
Gene and transcription
Genbank (Entrez)AF106046 AK000332 AK313548 AW242551 BC028373
RefSeq transcript (Entrez)NM_001134665 NM_001134666 NM_001375880 NM_001375881 NM_001375882 NM_152292
Consensus coding sequences : CCDS (NCBI)TRMT10A
Gene ExpressionTRMT10A [ NCBI-GEO ]   TRMT10A [ EBI - ARRAY_EXPRESS ]   TRMT10A [ SEEK ]   TRMT10A [ MEM ]
Gene Expression Viewer (FireBrowse)TRMT10A [ Firebrowse - Broad ]
GenevisibleExpression of TRMT10A in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)93587
GTEX Portal (Tissue expression)TRMT10A
Human Protein AtlasENSG00000145331-TRMT10A [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8TBZ6   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8TBZ6  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8TBZ6
PhosPhoSitePlusQ8TBZ6
Domaine pattern : Prosite (Expaxy)SAM_MT_TRM10 (PS51675)   
Domains : Interpro (EBI)MT_TRM10-typ    MT_TRM10-typ_sf    TRM10/TRM10A    tRNA_m1G_MeTrfase_euk    tRNA_MeTrfase_TRMD/TRM10   
Domain families : Pfam (Sanger)tRNA_m1G_MT (PF01746)   
Domain families : Pfam (NCBI)pfam01746   
Conserved Domain (NCBI)TRMT10A
PDB (RSDB)4FMW   
PDB Europe4FMW   
PDB (PDBSum)4FMW   
PDB (IMB)4FMW   
Structural Biology KnowledgeBase4FMW   
SCOP (Structural Classification of Proteins)4FMW   
CATH (Classification of proteins structures)4FMW   
SuperfamilyQ8TBZ6
AlphaFold pdb e-kbQ8TBZ6   
Human Protein Atlas [tissue]ENSG00000145331-TRMT10A [tissue]
HPRD15241
Protein Interaction databases
DIP (DOE-UCLA)Q8TBZ6
IntAct (EBI)Q8TBZ6
BioGRIDTRMT10A
STRING (EMBL)TRMT10A
ZODIACTRMT10A
Ontologies - Pathways
QuickGOQ8TBZ6
Ontology : AmiGOtRNA binding  tRNA binding  tRNA N1-guanine methylation  RNA binding  protein binding  nucleus  nucleus  nucleoplasm  nucleoplasm  nucleolus  mitochondrion  cytosol  cytosol  tRNA (guanine-N1-)-methyltransferase activity  tRNA (guanine-N1-)-methyltransferase activity  actin cytoskeleton  tRNA methylation  tRNA (guanine(9)-N(1))-methyltransferase activity  extracellular exosome  mitochondrial tRNA processing  
Ontology : EGO-EBItRNA binding  tRNA binding  tRNA N1-guanine methylation  RNA binding  protein binding  nucleus  nucleus  nucleoplasm  nucleoplasm  nucleolus  mitochondrion  cytosol  cytosol  tRNA (guanine-N1-)-methyltransferase activity  tRNA (guanine-N1-)-methyltransferase activity  actin cytoskeleton  tRNA methylation  tRNA (guanine(9)-N(1))-methyltransferase activity  extracellular exosome  mitochondrial tRNA processing  
NDEx NetworkTRMT10A
Atlas of Cancer Signalling NetworkTRMT10A
Wikipedia pathwaysTRMT10A
Orthology - Evolution
OrthoDB93587
GeneTree (enSembl)ENSG00000145331
Phylogenetic Trees/Animal Genes : TreeFamTRMT10A
Homologs : HomoloGeneTRMT10A
Homology/Alignments : Family Browser (UCSC)TRMT10A
Gene fusions - Rearrangements
Fusion : QuiverTRMT10A
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTRMT10A [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TRMT10A
dbVarTRMT10A
ClinVarTRMT10A
MonarchTRMT10A
1000_GenomesTRMT10A 
Exome Variant ServerTRMT10A
GNOMAD BrowserENSG00000145331
Varsome BrowserTRMT10A
ACMGTRMT10A variants
VarityQ8TBZ6
Genomic Variants (DGV)TRMT10A [DGVbeta]
DECIPHERTRMT10A [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTRMT10A 
Mutations
ICGC Data PortalTRMT10A 
TCGA Data PortalTRMT10A 
Broad Tumor PortalTRMT10A
OASIS PortalTRMT10A [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTRMT10A  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DTRMT10A
Mutations and Diseases : HGMDTRMT10A
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaTRMT10A
DgiDB (Drug Gene Interaction Database)TRMT10A
DoCM (Curated mutations)TRMT10A
CIViC (Clinical Interpretations of Variants in Cancer)TRMT10A
Cancer3DTRMT10A
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM616013    616033   
Orphanet22619   
DisGeNETTRMT10A
MedgenTRMT10A
Genetic Testing Registry TRMT10A
NextProtQ8TBZ6 [Medical]
GENETestsTRMT10A
Target ValidationTRMT10A
Huge Navigator TRMT10A [HugePedia]
ClinGenTRMT10A
Clinical trials, drugs, therapy
MyCancerGenomeTRMT10A
Protein Interactions : CTDTRMT10A
Pharm GKB GenePA134979919
PharosQ8TBZ6
Clinical trialTRMT10A
Miscellaneous
canSAR (ICR)TRMT10A
HarmonizomeTRMT10A
DataMed IndexTRMT10A
Probes
Litterature
PubMed18 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXTRMT10A
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 15:36:27 CEST 2021

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