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TRMT12 (tRNA methyltransferase 12 homolog)

Identity

Alias_namestRNA methyltranferase 12 homolog (S. cerevisiae)
tRNA methyltransferase 12 homolog (S. cerevisiae)
Alias_symbol (synonym)FLJ20772
Trm12
TYW2
Other aliasTRM12
HGNC (Hugo) TRMT12
LocusID (NCBI) 55039
Atlas_Id 46933
Location 8q24.13  [Link to chromosome band 8q24]
Location_base_pair Starts at 124450807 and ends at 124453025 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
WDR74 (11q12.3) / TRMT12 (8q24.13)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)TRMT12   26091
Cards
Entrez_Gene (NCBI)TRMT12  55039  tRNA methyltransferase 12 homolog
AliasesTRM12; TYW2
GeneCards (Weizmann)TRMT12
Ensembl hg19 (Hinxton)ENSG00000183665 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000183665 [Gene_View]  ENSG00000183665 [Sequence]  chr8:124450807-124453025 [Contig_View]  TRMT12 [Vega]
ICGC DataPortalENSG00000183665
TCGA cBioPortalTRMT12
AceView (NCBI)TRMT12
Genatlas (Paris)TRMT12
WikiGenes55039
SOURCE (Princeton)TRMT12
Genetics Home Reference (NIH)TRMT12
Genomic and cartography
GoldenPath hg38 (UCSC)TRMT12  -     chr8:124450807-124453025 +  8q24.13   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TRMT12  -     8q24.13   [Description]    (hg19-Feb_2009)
GoldenPathTRMT12 - 8q24.13 [CytoView hg19]  TRMT12 - 8q24.13 [CytoView hg38]
ImmunoBaseENSG00000183665
Mapping of homologs : NCBITRMT12 [Mapview hg19]  TRMT12 [Mapview hg38]
OMIM611244   
Gene and transcription
Genbank (Entrez)AA608716 AK000779 AK222727 AK225083 BC003057
RefSeq transcript (Entrez)NM_017956
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)TRMT12
Cluster EST : UnigeneHs.9925 [ NCBI ]
CGAP (NCI)Hs.9925
Alternative Splicing GalleryENSG00000183665
Gene ExpressionTRMT12 [ NCBI-GEO ]   TRMT12 [ EBI - ARRAY_EXPRESS ]   TRMT12 [ SEEK ]   TRMT12 [ MEM ]
Gene Expression Viewer (FireBrowse)TRMT12 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)55039
GTEX Portal (Tissue expression)TRMT12
Human Protein AtlasENSG00000183665-TRMT12 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ53H54   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ53H54  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ53H54
Splice isoforms : SwissVarQ53H54
PhosPhoSitePlusQ53H54
Domaine pattern : Prosite (Expaxy)SAM_MT_TRM5_TYW2 (PS51684)   
Domains : Interpro (EBI)MeTrfase_TRM5/TYW2    SAM-dependent_MTases   
Domain families : Pfam (Sanger)Met_10 (PF02475)   
Domain families : Pfam (NCBI)pfam02475   
Conserved Domain (NCBI)TRMT12
DMDM Disease mutations55039
Blocks (Seattle)TRMT12
SuperfamilyQ53H54
Human Protein Atlas [tissue]ENSG00000183665-TRMT12 [tissue]
Peptide AtlasQ53H54
HPRD07947
IPIIPI00329723   IPI00973790   
Protein Interaction databases
DIP (DOE-UCLA)Q53H54
IntAct (EBI)Q53H54
FunCoupENSG00000183665
BioGRIDTRMT12
STRING (EMBL)TRMT12
ZODIACTRMT12
Ontologies - Pathways
QuickGOQ53H54
Ontology : AmiGOprotein binding  cytoplasm  tRNA methyltransferase activity  tRNA methylation  wybutosine biosynthetic process  tRNA 4-demethylwyosine alpha-amino-alpha-carboxypropyltransferase activity  
Ontology : EGO-EBIprotein binding  cytoplasm  tRNA methyltransferase activity  tRNA methylation  wybutosine biosynthetic process  tRNA 4-demethylwyosine alpha-amino-alpha-carboxypropyltransferase activity  
NDEx NetworkTRMT12
Atlas of Cancer Signalling NetworkTRMT12
Wikipedia pathwaysTRMT12
Orthology - Evolution
OrthoDB55039
GeneTree (enSembl)ENSG00000183665
Phylogenetic Trees/Animal Genes : TreeFamTRMT12
HOGENOMQ53H54
Homologs : HomoloGeneTRMT12
Homology/Alignments : Family Browser (UCSC)TRMT12
Gene fusions - Rearrangements
Fusion : QuiverTRMT12
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTRMT12 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TRMT12
dbVarTRMT12
ClinVarTRMT12
1000_GenomesTRMT12 
Exome Variant ServerTRMT12
ExAC (Exome Aggregation Consortium)ENSG00000183665
GNOMAD BrowserENSG00000183665
Varsome BrowserTRMT12
Genetic variants : HAPMAP55039
Genomic Variants (DGV)TRMT12 [DGVbeta]
DECIPHERTRMT12 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTRMT12 
Mutations
ICGC Data PortalTRMT12 
TCGA Data PortalTRMT12 
Broad Tumor PortalTRMT12
OASIS PortalTRMT12 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTRMT12  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DTRMT12
Mutations and Diseases : HGMDTRMT12
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch TRMT12
DgiDB (Drug Gene Interaction Database)TRMT12
DoCM (Curated mutations)TRMT12 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)TRMT12 (select a term)
intoGenTRMT12
Cancer3DTRMT12(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM611244   
Orphanet
DisGeNETTRMT12
MedgenTRMT12
Genetic Testing Registry TRMT12
NextProtQ53H54 [Medical]
TSGene55039
GENETestsTRMT12
Target ValidationTRMT12
Huge Navigator TRMT12 [HugePedia]
snp3D : Map Gene to Disease55039
BioCentury BCIQTRMT12
ClinGenTRMT12
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD55039
Chemical/Pharm GKB GenePA142670700
Clinical trialTRMT12
Miscellaneous
canSAR (ICR)TRMT12 (select the gene name)
DataMed IndexTRMT12
Probes
Litterature
PubMed11 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTRMT12
EVEXTRMT12
GoPubMedTRMT12
iHOPTRMT12
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Aug 12 16:00:34 CEST 2019
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