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TRMT1L (tRNA methyltransferase 1 like)

Identity

Alias_namesC1orf25
chromosome 1 open reading frame 25
TRM1 tRNA methyltransferase 1-like
tRNA methyltransferase 1 homolog (S. cerevisiae)-like
tRNA methyltransferase 1-like
Other aliasMST070
MSTP070
TRM1L
bG120K12.3
HGNC (Hugo) TRMT1L
LocusID (NCBI) 81627
Atlas_Id 54724
Location 1q25.3  [Link to chromosome band 1q25]
Location_base_pair Starts at 185118086 and ends at 185157098 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
XPR1 (1q25.3) / TRMT1L (1q25.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 1 ]
  Lung: Translocations in Small Cell Carcinoma


External links

Nomenclature
HGNC (Hugo)TRMT1L   16782
Cards
Entrez_Gene (NCBI)TRMT1L  81627  tRNA methyltransferase 1 like
AliasesC1orf25; MST070; MSTP070; TRM1L; 
bG120K12.3
GeneCards (Weizmann)TRMT1L
Ensembl hg19 (Hinxton)ENSG00000121486 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000121486 [Gene_View]  chr1:185118086-185157098 [Contig_View]  TRMT1L [Vega]
ICGC DataPortalENSG00000121486
TCGA cBioPortalTRMT1L
AceView (NCBI)TRMT1L
Genatlas (Paris)TRMT1L
WikiGenes81627
SOURCE (Princeton)TRMT1L
Genetics Home Reference (NIH)TRMT1L
Genomic and cartography
GoldenPath hg38 (UCSC)TRMT1L  -     chr1:185118086-185157098 -  1q25.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TRMT1L  -     1q25.3   [Description]    (hg19-Feb_2009)
EnsemblTRMT1L - 1q25.3 [CytoView hg19]  TRMT1L - 1q25.3 [CytoView hg38]
Mapping of homologs : NCBITRMT1L [Mapview hg19]  TRMT1L [Mapview hg38]
OMIM611673   
Gene and transcription
Genbank (Entrez)AF163261 AF288399 AK027418 AK074936 AK074993
RefSeq transcript (Entrez)NM_001202423 NM_030934
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)TRMT1L
Cluster EST : UnigeneHs.107149 [ NCBI ]
CGAP (NCI)Hs.107149
Alternative Splicing GalleryENSG00000121486
Gene ExpressionTRMT1L [ NCBI-GEO ]   TRMT1L [ EBI - ARRAY_EXPRESS ]   TRMT1L [ SEEK ]   TRMT1L [ MEM ]
Gene Expression Viewer (FireBrowse)TRMT1L [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)81627
GTEX Portal (Tissue expression)TRMT1L
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ7Z2T5   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ7Z2T5  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ7Z2T5
Splice isoforms : SwissVarQ7Z2T5
PhosPhoSitePlusQ7Z2T5
Domaine pattern : Prosite (Expaxy)SAM_MT_TRM1 (PS51626)    ZINC_FINGER_C2H2_1 (PS00028)    ZINC_FINGER_C2H2_2 (PS50157)   
Domains : Interpro (EBI)SAM-dependent_MTases    Trm1    Znf_C2H2    Znf_C2H2-like   
Domain families : Pfam (Sanger)TRM (PF02005)   
Domain families : Pfam (NCBI)pfam02005   
Domain families : Smart (EMBL)ZnF_C2H2 (SM00355)  
Conserved Domain (NCBI)TRMT1L
DMDM Disease mutations81627
Blocks (Seattle)TRMT1L
SuperfamilyQ7Z2T5
Human Protein AtlasENSG00000121486
Peptide AtlasQ7Z2T5
HPRD12722
IPIIPI00334914   IPI00844404   IPI00646783   
Protein Interaction databases
DIP (DOE-UCLA)Q7Z2T5
IntAct (EBI)Q7Z2T5
FunCoupENSG00000121486
BioGRIDTRMT1L
STRING (EMBL)TRMT1L
ZODIACTRMT1L
Ontologies - Pathways
QuickGOQ7Z2T5
Ontology : AmiGOtRNA binding  RNA binding  tRNA (guanine-N2-)-methyltransferase activity  behavior  tRNA methylation  metal ion binding  
Ontology : EGO-EBItRNA binding  RNA binding  tRNA (guanine-N2-)-methyltransferase activity  behavior  tRNA methylation  metal ion binding  
NDEx NetworkTRMT1L
Atlas of Cancer Signalling NetworkTRMT1L
Wikipedia pathwaysTRMT1L
Orthology - Evolution
OrthoDB81627
GeneTree (enSembl)ENSG00000121486
Phylogenetic Trees/Animal Genes : TreeFamTRMT1L
HOVERGENQ7Z2T5
HOGENOMQ7Z2T5
Homologs : HomoloGeneTRMT1L
Homology/Alignments : Family Browser (UCSC)TRMT1L
Gene fusions - Rearrangements
Fusion : MitelmanXPR1/TRMT1L [1q25.3/1q25.3]  [t(1;1)(q25;q25)]  
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTRMT1L [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TRMT1L
dbVarTRMT1L
ClinVarTRMT1L
1000_GenomesTRMT1L 
Exome Variant ServerTRMT1L
ExAC (Exome Aggregation Consortium)TRMT1L (select the gene name)
Genetic variants : HAPMAP81627
Genomic Variants (DGV)TRMT1L [DGVbeta]
DECIPHERTRMT1L [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTRMT1L 
Mutations
ICGC Data PortalTRMT1L 
TCGA Data PortalTRMT1L 
Broad Tumor PortalTRMT1L
OASIS PortalTRMT1L [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTRMT1L  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDTRMT1L
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch TRMT1L
DgiDB (Drug Gene Interaction Database)TRMT1L
DoCM (Curated mutations)TRMT1L (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)TRMT1L (select a term)
intoGenTRMT1L
Cancer3DTRMT1L(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM611673   
Orphanet
MedgenTRMT1L
Genetic Testing Registry TRMT1L
NextProtQ7Z2T5 [Medical]
TSGene81627
GENETestsTRMT1L
Huge Navigator TRMT1L [HugePedia]
snp3D : Map Gene to Disease81627
BioCentury BCIQTRMT1L
ClinGenTRMT1L
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD81627
Chemical/Pharm GKB GenePA25612
Clinical trialTRMT1L
Miscellaneous
canSAR (ICR)TRMT1L (select the gene name)
Probes
Litterature
PubMed23 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTRMT1L
EVEXTRMT1L
GoPubMedTRMT1L
iHOPTRMT1L
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Fri May 19 12:42:21 CEST 2017

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