TRMT61A (tRNA methyltransferase 61A)

2014-11-01  

Identity

HGNC
LOCATION
14q32.33
LOCUSID
ALIAS
C14orf172,GCD14,Gcd14p,TRM61,hTRM61
FUSION GENES

Other Information

Locus ID:

NCBI: 115708
HGNC: 23790
Ensembl: ENSG00000166166

Variants:

dbSNP: 115708
ClinVar: 115708
TCGA: ENSG00000166166
COSMIC: TRMT61A

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000166166ENST00000299202H0Y2Q1
ENSG00000166166ENST00000389749Q96FX7
ENSG00000166166ENST00000389749A0A024R6Q2

Expression (GTEx)

0
5
10
15
20
25
30
35
40
45
50

Pathways

PathwaySourceExternal ID
Gene ExpressionREACTOMER-HSA-74160
tRNA processingREACTOMER-HSA-72306
tRNA modification in the nucleus and cytosolREACTOMER-HSA-6782315

References

Pubmed IDYearTitleCitations
262346762016TRM6/61 connects PKCα with translational control through tRNAi(Met) stabilization: impact on tumorigenesis.10
264709192015Crystal Structure of the Human tRNA m(1)A58 Methyltransferase-tRNA(3)(Lys) Complex: Refolding of Substrate tRNA Allows Access to the Methylation Target.10

Citation

Dessen P

TRMT61A (tRNA methyltransferase 61A)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/75201/trmt61a