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TRMT61A (tRNA methyltransferase 61A)

Identity

Alias (NCBI)C14orf172
GCD14
Gcd14p
TRM61
hTRM61
HGNC (Hugo) TRMT61A
HGNC Alias symbFLJ40452
GCD14
Gcd14p
hTRM61
HGNC Previous nameC14orf172
HGNC Previous namechromosome 14 open reading frame 172
 tRNA methyltransferase 61 homolog A (S. cerevisiae)
LocusID (NCBI) 115708
Atlas_Id 75201
Location 14q32.33  [Link to chromosome band 14q32]
Location_base_pair Starts at 103529196 and ends at 103537073 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
NINJ1 (9q22.31) / TRMT61A (14q32.32)TRMT61A (14q32.32) / TRMT61A (14q32.32)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)TRMT61A   23790
Cards
Entrez_Gene (NCBI)TRMT61A    tRNA methyltransferase 61A
AliasesC14orf172; GCD14; Gcd14p; TRM61; 
hTRM61
GeneCards (Weizmann)TRMT61A
Ensembl hg19 (Hinxton)ENSG00000166166 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000166166 [Gene_View]  ENSG00000166166 [Sequence]  chr14:103529196-103537073 [Contig_View]  TRMT61A [Vega]
ICGC DataPortalENSG00000166166
TCGA cBioPortalTRMT61A
AceView (NCBI)TRMT61A
Genatlas (Paris)TRMT61A
SOURCE (Princeton)TRMT61A
Genetics Home Reference (NIH)TRMT61A
Genomic and cartography
GoldenPath hg38 (UCSC)TRMT61A  -     chr14:103529196-103537073 +  14q32.33   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TRMT61A  -     14q32.33   [Description]    (hg19-Feb_2009)
GoldenPathTRMT61A - 14q32.33 [CytoView hg19]  TRMT61A - 14q32.33 [CytoView hg38]
ImmunoBaseENSG00000166166
Genome Data Viewer NCBITRMT61A [Mapview hg19]  
Gene and transcription
Genbank (Entrez)AK097771 BC007241 BC010167 BC016033 BQ015210
RefSeq transcript (Entrez)NM_152307
Consensus coding sequences : CCDS (NCBI)TRMT61A
Gene ExpressionTRMT61A [ NCBI-GEO ]   TRMT61A [ EBI - ARRAY_EXPRESS ]   TRMT61A [ SEEK ]   TRMT61A [ MEM ]
Gene Expression Viewer (FireBrowse)TRMT61A [ Firebrowse - Broad ]
GenevisibleExpression of TRMT61A in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)115708
GTEX Portal (Tissue expression)TRMT61A
Human Protein AtlasENSG00000166166-TRMT61A [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96FX7   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ96FX7  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ96FX7
PhosPhoSitePlusQ96FX7
Domaine pattern : Prosite (Expaxy)SAM_TRM61 (PS51620)   
Domains : Interpro (EBI)SAM-dependent_MTases    tRNA_MeTrfase_Gcd14   
Domain families : Pfam (Sanger)GCD14 (PF08704)   
Domain families : Pfam (NCBI)pfam08704   
Conserved Domain (NCBI)TRMT61A
PDB (RSDB)5CCB    5CCX    5CD1   
PDB Europe5CCB    5CCX    5CD1   
PDB (PDBSum)5CCB    5CCX    5CD1   
PDB (IMB)5CCB    5CCX    5CD1   
Structural Biology KnowledgeBase5CCB    5CCX    5CD1   
SCOP (Structural Classification of Proteins)5CCB    5CCX    5CD1   
CATH (Classification of proteins structures)5CCB    5CCX    5CD1   
SuperfamilyQ96FX7
AlphaFold pdb e-kbQ96FX7   
Human Protein Atlas [tissue]ENSG00000166166-TRMT61A [tissue]
HPRD08810
Protein Interaction databases
DIP (DOE-UCLA)Q96FX7
IntAct (EBI)Q96FX7
BioGRIDTRMT61A
STRING (EMBL)TRMT61A
ZODIACTRMT61A
Ontologies - Pathways
QuickGOQ96FX7
Ontology : AmiGOprotein binding  nucleus  nucleoplasm  tRNA modification  tRNA (adenine-N1-)-methyltransferase activity  tRNA methylation  tRNA (m1A) methyltransferase complex  mRNA (adenine-N1-)-methyltransferase activity  mRNA methylation  
Ontology : EGO-EBIprotein binding  nucleus  nucleoplasm  tRNA modification  tRNA (adenine-N1-)-methyltransferase activity  tRNA methylation  tRNA (m1A) methyltransferase complex  mRNA (adenine-N1-)-methyltransferase activity  mRNA methylation  
NDEx NetworkTRMT61A
Atlas of Cancer Signalling NetworkTRMT61A
Wikipedia pathwaysTRMT61A
Orthology - Evolution
OrthoDB115708
GeneTree (enSembl)ENSG00000166166
Phylogenetic Trees/Animal Genes : TreeFamTRMT61A
Homologs : HomoloGeneTRMT61A
Homology/Alignments : Family Browser (UCSC)TRMT61A
Gene fusions - Rearrangements
Fusion : QuiverTRMT61A
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTRMT61A [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TRMT61A
dbVarTRMT61A
ClinVarTRMT61A
MonarchTRMT61A
1000_GenomesTRMT61A 
Exome Variant ServerTRMT61A
GNOMAD BrowserENSG00000166166
Varsome BrowserTRMT61A
ACMGTRMT61A variants
VarityQ96FX7
Genomic Variants (DGV)TRMT61A [DGVbeta]
DECIPHERTRMT61A [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTRMT61A 
Mutations
ICGC Data PortalTRMT61A 
TCGA Data PortalTRMT61A 
Broad Tumor PortalTRMT61A
OASIS PortalTRMT61A [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTRMT61A  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DTRMT61A
Mutations and Diseases : HGMDTRMT61A
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaTRMT61A
DgiDB (Drug Gene Interaction Database)TRMT61A
DoCM (Curated mutations)TRMT61A
CIViC (Clinical Interpretations of Variants in Cancer)TRMT61A
Cancer3DTRMT61A
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
DisGeNETTRMT61A
MedgenTRMT61A
Genetic Testing Registry TRMT61A
NextProtQ96FX7 [Medical]
GENETestsTRMT61A
Target ValidationTRMT61A
Huge Navigator TRMT61A [HugePedia]
ClinGenTRMT61A
Clinical trials, drugs, therapy
MyCancerGenomeTRMT61A
Protein Interactions : CTDTRMT61A
Pharm GKB GenePA164726783
PharosQ96FX7
Clinical trialTRMT61A
Miscellaneous
canSAR (ICR)TRMT61A
HarmonizomeTRMT61A
DataMed IndexTRMT61A
Probes
Litterature
PubMed23 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXTRMT61A
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 16:27:03 CEST 2021

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