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TROVE2 (TROVE domain family member 2)

Identity

Alias_namesSSA2
Sjogren syndrome antigen A2 (60kDa, ribonucleoprotein autoantigen SS-A/Ro)
TROVE domain family, member 2
Alias_symbol (synonym)Ro60
Other aliasRO60
RORNP
HGNC (Hugo) TROVE2
LocusID (NCBI) 6738
Atlas_Id 75207
Location 1q31.2  [Link to chromosome band 1q31]
Location_base_pair Starts at 193059874 and ends at 193091776 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
CALM3 (19q13.32) / TROVE2 (1q31.2)KCNIP1 (5q35.1) / TROVE2 (1q31.2)TROVE2 (1q31.2) / CACNA1S (1q32.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)TROVE2   11313
Cards
Entrez_Gene (NCBI)TROVE2  6738  TROVE domain family member 2
AliasesRO60; RORNP; SSA2
GeneCards (Weizmann)TROVE2
Ensembl hg19 (Hinxton)ENSG00000116747 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000116747 [Gene_View]  chr1:193059874-193091776 [Contig_View]  TROVE2 [Vega]
ICGC DataPortalENSG00000116747
TCGA cBioPortalTROVE2
AceView (NCBI)TROVE2
Genatlas (Paris)TROVE2
WikiGenes6738
SOURCE (Princeton)TROVE2
Genetics Home Reference (NIH)TROVE2
Genomic and cartography
GoldenPath hg38 (UCSC)TROVE2  -     chr1:193059874-193091776 +  1q31.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TROVE2  -     1q31.2   [Description]    (hg19-Feb_2009)
EnsemblTROVE2 - 1q31.2 [CytoView hg19]  TROVE2 - 1q31.2 [CytoView hg38]
Mapping of homologs : NCBITROVE2 [Mapview hg19]  TROVE2 [Mapview hg38]
OMIM600063   
Gene and transcription
Genbank (Entrez)AH003763 AI433657 AK314594 AY205314 AY205315
RefSeq transcript (Entrez)NM_001042369 NM_001042370 NM_001173524 NM_001173525 NM_001331020 NM_004600
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)TROVE2
Cluster EST : UnigeneHs.288178 [ NCBI ]
CGAP (NCI)Hs.288178
Alternative Splicing GalleryENSG00000116747
Gene ExpressionTROVE2 [ NCBI-GEO ]   TROVE2 [ EBI - ARRAY_EXPRESS ]   TROVE2 [ SEEK ]   TROVE2 [ MEM ]
Gene Expression Viewer (FireBrowse)TROVE2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)6738
GTEX Portal (Tissue expression)TROVE2
Protein : pattern, domain, 3D structure
UniProt/SwissProtP10155   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP10155  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP10155
Splice isoforms : SwissVarP10155
PhosPhoSitePlusP10155
Domaine pattern : Prosite (Expaxy)TROVE (PS50988)   
Domains : Interpro (EBI)TROVE_dom    VWF_A   
Domain families : Pfam (Sanger)TROVE (PF05731)   
Domain families : Pfam (NCBI)pfam05731   
Conserved Domain (NCBI)TROVE2
DMDM Disease mutations6738
Blocks (Seattle)TROVE2
SuperfamilyP10155
Human Protein AtlasENSG00000116747
Peptide AtlasP10155
HPRD15964
IPIIPI00019450   IPI00219287   IPI00760707   IPI00642416   IPI00646322   IPI00646813   IPI00642895   IPI00969077   IPI00966215   
Protein Interaction databases
DIP (DOE-UCLA)P10155
IntAct (EBI)P10155
FunCoupENSG00000116747
BioGRIDTROVE2
STRING (EMBL)TROVE2
ZODIACTROVE2
Ontologies - Pathways
QuickGOP10155
Ontology : AmiGOimmune system development  RNA binding  nucleoplasm  cytosol  transcription from RNA polymerase III promoter  smoothened signaling pathway  response to UV  intracellular ribonucleoprotein complex  U2 snRNA binding  metal ion binding  cilium assembly  
Ontology : EGO-EBIimmune system development  RNA binding  nucleoplasm  cytosol  transcription from RNA polymerase III promoter  smoothened signaling pathway  response to UV  intracellular ribonucleoprotein complex  U2 snRNA binding  metal ion binding  cilium assembly  
Pathways : KEGGSystemic lupus erythematosus   
NDEx NetworkTROVE2
Atlas of Cancer Signalling NetworkTROVE2
Wikipedia pathwaysTROVE2
Orthology - Evolution
OrthoDB6738
GeneTree (enSembl)ENSG00000116747
Phylogenetic Trees/Animal Genes : TreeFamTROVE2
HOVERGENP10155
HOGENOMP10155
Homologs : HomoloGeneTROVE2
Homology/Alignments : Family Browser (UCSC)TROVE2
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTROVE2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TROVE2
dbVarTROVE2
ClinVarTROVE2
1000_GenomesTROVE2 
Exome Variant ServerTROVE2
ExAC (Exome Aggregation Consortium)TROVE2 (select the gene name)
Genetic variants : HAPMAP6738
Genomic Variants (DGV)TROVE2 [DGVbeta]
DECIPHERTROVE2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTROVE2 
Mutations
ICGC Data PortalTROVE2 
TCGA Data PortalTROVE2 
Broad Tumor PortalTROVE2
OASIS PortalTROVE2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTROVE2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDTROVE2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch TROVE2
DgiDB (Drug Gene Interaction Database)TROVE2
DoCM (Curated mutations)TROVE2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)TROVE2 (select a term)
intoGenTROVE2
Cancer3DTROVE2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM600063   
Orphanet
MedgenTROVE2
Genetic Testing Registry TROVE2
NextProtP10155 [Medical]
TSGene6738
GENETestsTROVE2
Target ValidationTROVE2
Huge Navigator TROVE2 [HugePedia]
snp3D : Map Gene to Disease6738
BioCentury BCIQTROVE2
ClinGenTROVE2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD6738
Chemical/Pharm GKB GenePA36137
Clinical trialTROVE2
Miscellaneous
canSAR (ICR)TROVE2 (select the gene name)
Probes
Litterature
PubMed47 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTROVE2
EVEXTROVE2
GoPubMedTROVE2
iHOPTROVE2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed May 31 15:47:17 CEST 2017

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