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TRPA1 (transient receptor potential cation channel subfamily A member 1)

Identity

Alias_namesANKTM1
ankyrin-like with transmembrane domains 1
transient receptor potential cation channel, subfamily A, member 1
Other aliasFEPS
HGNC (Hugo) TRPA1
LocusID (NCBI) 8989
Atlas_Id 52884
Location 8q13.3  [Link to chromosome band 8q13]
Location_base_pair Starts at 72933486 and ends at 72987819 bp from pter ( according to hg19-Feb_2009)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)TRPA1   497
Cards
Entrez_Gene (NCBI)TRPA1  8989  transient receptor potential cation channel subfamily A member 1
AliasesANKTM1; FEPS
GeneCards (Weizmann)TRPA1
Ensembl hg19 (Hinxton)ENSG00000104321 [Gene_View]  chr8:72933486-72987819 [Contig_View]  TRPA1 [Vega]
Ensembl hg38 (Hinxton)ENSG00000104321 [Gene_View]  chr8:72933486-72987819 [Contig_View]  TRPA1 [Vega]
ICGC DataPortalENSG00000104321
TCGA cBioPortalTRPA1
AceView (NCBI)TRPA1
Genatlas (Paris)TRPA1
WikiGenes8989
SOURCE (Princeton)TRPA1
Genetics Home Reference (NIH)TRPA1
Genomic and cartography
GoldenPath hg19 (UCSC)TRPA1  -     chr8:72933486-72987819 -  8q13.3   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)TRPA1  -     8q13.3   [Description]    (hg38-Dec_2013)
EnsemblTRPA1 - 8q13.3 [CytoView hg19]  TRPA1 - 8q13.3 [CytoView hg38]
Mapping of homologs : NCBITRPA1 [Mapview hg19]  TRPA1 [Mapview hg38]
OMIM604775   615040   
Gene and transcription
Genbank (Entrez)AK307942 BC148423 BC153003 Y10601
RefSeq transcript (Entrez)NM_007332
RefSeq genomic (Entrez)NC_000008 NC_018919 NG_033890 NT_008183 NW_004929339
Consensus coding sequences : CCDS (NCBI)TRPA1
Cluster EST : UnigeneHs.716816 [ NCBI ]
CGAP (NCI)Hs.716816
Alternative Splicing GalleryENSG00000104321
Gene ExpressionTRPA1 [ NCBI-GEO ]   TRPA1 [ EBI - ARRAY_EXPRESS ]   TRPA1 [ SEEK ]   TRPA1 [ MEM ]
Gene Expression Viewer (FireBrowse)TRPA1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)8989
GTEX Portal (Tissue expression)TRPA1
Protein : pattern, domain, 3D structure
UniProt/SwissProtO75762   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO75762  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO75762
Splice isoforms : SwissVarO75762
PhosPhoSitePlusO75762
Domaine pattern : Prosite (Expaxy)ANK_REP_REGION (PS50297)    ANK_REPEAT (PS50088)   
Domains : Interpro (EBI)Ankyrin_rpt    Ankyrin_rpt-contain_dom    Ion_trans_dom   
Domain families : Pfam (Sanger)Ank_2 (PF12796)    Ion_trans (PF00520)   
Domain families : Pfam (NCBI)pfam12796    pfam00520   
Domain families : Smart (EMBL)ANK (SM00248)  
Conserved Domain (NCBI)TRPA1
DMDM Disease mutations8989
Blocks (Seattle)TRPA1
PDB (SRS)3J9P   
PDB (PDBSum)3J9P   
PDB (IMB)3J9P   
PDB (RSDB)3J9P   
Structural Biology KnowledgeBase3J9P   
SCOP (Structural Classification of Proteins)3J9P   
CATH (Classification of proteins structures)3J9P   
SuperfamilyO75762
Human Protein AtlasENSG00000104321
Peptide AtlasO75762
HPRD09208
IPIIPI00015963   IPI00980507   
Protein Interaction databases
DIP (DOE-UCLA)O75762
IntAct (EBI)O75762
FunCoupENSG00000104321
BioGRIDTRPA1
STRING (EMBL)TRPA1
ZODIACTRPA1
Ontologies - Pathways
QuickGOO75762
Ontology : AmiGOcalcium channel activity  intracellular  intracellular  plasma membrane  integral component of plasma membrane  ion transport  cell surface receptor signaling pathway  response to cold  response to organic substance  response to organic cyclic compound  channel activity  calcium-release channel activity  calcium-release channel activity  sensory perception of pain  stereocilium bundle  response to drug  response to hydrogen peroxide  response to pain  thermoception  detection of mechanical stimulus involved in sensory perception of pain  detection of chemical stimulus involved in sensory perception of pain  release of sequestered calcium ion into cytosol  release of sequestered calcium ion into cytosol  protein homotetramerization  calcium ion transmembrane transport  calcium ion transmembrane transport  temperature-gated cation channel activity  
Ontology : EGO-EBIcalcium channel activity  intracellular  intracellular  plasma membrane  integral component of plasma membrane  ion transport  cell surface receptor signaling pathway  response to cold  response to organic substance  response to organic cyclic compound  channel activity  calcium-release channel activity  calcium-release channel activity  sensory perception of pain  stereocilium bundle  response to drug  response to hydrogen peroxide  response to pain  thermoception  detection of mechanical stimulus involved in sensory perception of pain  detection of chemical stimulus involved in sensory perception of pain  release of sequestered calcium ion into cytosol  release of sequestered calcium ion into cytosol  protein homotetramerization  calcium ion transmembrane transport  calcium ion transmembrane transport  temperature-gated cation channel activity  
NDEx NetworkTRPA1
Atlas of Cancer Signalling NetworkTRPA1
Wikipedia pathwaysTRPA1
Orthology - Evolution
OrthoDB8989
GeneTree (enSembl)ENSG00000104321
Phylogenetic Trees/Animal Genes : TreeFamTRPA1
HOVERGENO75762
HOGENOMO75762
Homologs : HomoloGeneTRPA1
Homology/Alignments : Family Browser (UCSC)TRPA1
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTRPA1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TRPA1
dbVarTRPA1
ClinVarTRPA1
1000_GenomesTRPA1 
Exome Variant ServerTRPA1
ExAC (Exome Aggregation Consortium)TRPA1 (select the gene name)
Genetic variants : HAPMAP8989
Genomic Variants (DGV)TRPA1 [DGVbeta]
DECIPHER (Syndromes)8:72933486-72987819  ENSG00000104321
CONAN: Copy Number AnalysisTRPA1 
Mutations
ICGC Data PortalTRPA1 
TCGA Data PortalTRPA1 
Broad Tumor PortalTRPA1
OASIS PortalTRPA1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTRPA1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDTRPA1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch TRPA1
DgiDB (Drug Gene Interaction Database)TRPA1
DoCM (Curated mutations)TRPA1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)TRPA1 (select a term)
intoGenTRPA1
Cancer3DTRPA1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM604775    615040   
Orphanet22616   
MedgenTRPA1
Genetic Testing Registry TRPA1
NextProtO75762 [Medical]
TSGene8989
GENETestsTRPA1
Huge Navigator TRPA1 [HugePedia]
snp3D : Map Gene to Disease8989
BioCentury BCIQTRPA1
ClinGenTRPA1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD8989
Chemical/Pharm GKB GenePA24808
Clinical trialTRPA1
Miscellaneous
canSAR (ICR)TRPA1 (select the gene name)
Probes
Litterature
PubMed97 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTRPA1
EVEXTRPA1
GoPubMedTRPA1
iHOPTRPA1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Thu Mar 30 15:23:34 CEST 2017

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