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TRPC1 (transient receptor potential cation channel subfamily C member 1)

Identity

Alias_namestransient receptor potential cation channel
Alias_symbol (synonym)HTRP-1
Other aliasTRP1
HGNC (Hugo) TRPC1
LocusID (NCBI) 7220
Atlas_Id 43870
Location 3q23  [Link to chromosome band 3q23]
Location_base_pair Starts at 142724424 and ends at 142807887 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
TRPC1 (3q23) / PTPRG (3p14.2)TRPC1 3q23 / PTPRG 3p14.2

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)TRPC1   12333
Cards
Entrez_Gene (NCBI)TRPC1  7220  transient receptor potential cation channel subfamily C member 1
AliasesHTRP-1; TRP1
GeneCards (Weizmann)TRPC1
Ensembl hg19 (Hinxton)ENSG00000144935 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000144935 [Gene_View]  chr3:142724424-142807887 [Contig_View]  TRPC1 [Vega]
ICGC DataPortalENSG00000144935
TCGA cBioPortalTRPC1
AceView (NCBI)TRPC1
Genatlas (Paris)TRPC1
WikiGenes7220
SOURCE (Princeton)TRPC1
Genetics Home Reference (NIH)TRPC1
Genomic and cartography
GoldenPath hg38 (UCSC)TRPC1  -     chr3:142724424-142807887 +  3q23   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TRPC1  -     3q23   [Description]    (hg19-Feb_2009)
EnsemblTRPC1 - 3q23 [CytoView hg19]  TRPC1 - 3q23 [CytoView hg38]
Mapping of homologs : NCBITRPC1 [Mapview hg19]  TRPC1 [Mapview hg38]
OMIM602343   
Gene and transcription
Genbank (Entrez)AB255425 AF483645 AI280444 BC112338 BC113953
RefSeq transcript (Entrez)NM_001251845 NM_003304
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)TRPC1
Cluster EST : UnigeneHs.684389 [ NCBI ]
CGAP (NCI)Hs.684389
Alternative Splicing GalleryENSG00000144935
Gene ExpressionTRPC1 [ NCBI-GEO ]   TRPC1 [ EBI - ARRAY_EXPRESS ]   TRPC1 [ SEEK ]   TRPC1 [ MEM ]
Gene Expression Viewer (FireBrowse)TRPC1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)7220
GTEX Portal (Tissue expression)TRPC1
Protein : pattern, domain, 3D structure
UniProt/SwissProtP48995   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP48995  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP48995
Splice isoforms : SwissVarP48995
PhosPhoSitePlusP48995
Domains : Interpro (EBI)Ankyrin_rpt    Ankyrin_rpt-contain_dom    Ion_trans_dom    TRP_channel    TRP_dom    TRPC1_channel    TRPC_channel   
Domain families : Pfam (Sanger)Ion_trans (PF00520)    TRP_2 (PF08344)   
Domain families : Pfam (NCBI)pfam00520    pfam08344   
Domain families : Smart (EMBL)ANK (SM00248)  
Conserved Domain (NCBI)TRPC1
DMDM Disease mutations7220
Blocks (Seattle)TRPC1
SuperfamilyP48995
Human Protein AtlasENSG00000144935
Peptide AtlasP48995
HPRD11894
IPIIPI00012081   IPI00220579   IPI00941112   IPI00946570   
Protein Interaction databases
DIP (DOE-UCLA)P48995
IntAct (EBI)P48995
FunCoupENSG00000144935
BioGRIDTRPC1
STRING (EMBL)TRPC1
ZODIACTRPC1
Ontologies - Pathways
QuickGOP48995
Ontology : AmiGOcation channel activity  calcium channel activity  protein binding  plasma membrane  plasma membrane  integral component of plasma membrane  calcium ion transport  manganese ion transport  store-operated calcium channel activity  melanin biosynthetic process  receptor complex  positive regulation of release of sequestered calcium ion into cytosol  regulation of cytosolic calcium ion concentration  response to calcium ion  calcium ion transmembrane transport  inositol 1,4,5 trisphosphate binding  regulation of cardiac conduction  
Ontology : EGO-EBIcation channel activity  calcium channel activity  protein binding  plasma membrane  plasma membrane  integral component of plasma membrane  calcium ion transport  manganese ion transport  store-operated calcium channel activity  melanin biosynthetic process  receptor complex  positive regulation of release of sequestered calcium ion into cytosol  regulation of cytosolic calcium ion concentration  response to calcium ion  calcium ion transmembrane transport  inositol 1,4,5 trisphosphate binding  regulation of cardiac conduction  
Pathways : KEGGGlutamatergic synapse    Serotonergic synapse    Pancreatic secretion   
NDEx NetworkTRPC1
Atlas of Cancer Signalling NetworkTRPC1
Wikipedia pathwaysTRPC1
Orthology - Evolution
OrthoDB7220
GeneTree (enSembl)ENSG00000144935
Phylogenetic Trees/Animal Genes : TreeFamTRPC1
HOVERGENP48995
HOGENOMP48995
Homologs : HomoloGeneTRPC1
Homology/Alignments : Family Browser (UCSC)TRPC1
Gene fusions - Rearrangements
Fusion : MitelmanTRPC1/PTPRG [3q23/3p14.2]  
Fusion: TCGATRPC1 3q23 PTPRG 3p14.2 KIRC
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTRPC1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TRPC1
dbVarTRPC1
ClinVarTRPC1
1000_GenomesTRPC1 
Exome Variant ServerTRPC1
ExAC (Exome Aggregation Consortium)TRPC1 (select the gene name)
Genetic variants : HAPMAP7220
Genomic Variants (DGV)TRPC1 [DGVbeta]
DECIPHERTRPC1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTRPC1 
Mutations
ICGC Data PortalTRPC1 
TCGA Data PortalTRPC1 
Broad Tumor PortalTRPC1
OASIS PortalTRPC1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTRPC1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDTRPC1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch TRPC1
DgiDB (Drug Gene Interaction Database)TRPC1
DoCM (Curated mutations)TRPC1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)TRPC1 (select a term)
intoGenTRPC1
Cancer3DTRPC1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM602343   
Orphanet
MedgenTRPC1
Genetic Testing Registry TRPC1
NextProtP48995 [Medical]
TSGene7220
GENETestsTRPC1
Target ValidationTRPC1
Huge Navigator TRPC1 [HugePedia]
snp3D : Map Gene to Disease7220
BioCentury BCIQTRPC1
ClinGenTRPC1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD7220
Chemical/Pharm GKB GenePA357
Clinical trialTRPC1
Miscellaneous
canSAR (ICR)TRPC1 (select the gene name)
Probes
Litterature
PubMed145 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTRPC1
EVEXTRPC1
GoPubMedTRPC1
iHOPTRPC1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 25 19:36:27 CEST 2017

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