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TRPC4AP (transient receptor potential cation channel subfamily C member 4 associated protein)

Identity

Alias (NCBI)C20orf188
PPP1R158
TRRP4AP
TRUSS
HGNC (Hugo) TRPC4AP
HGNC Alias symbDKFZP727M231
DKFZp586C1223
dJ756N5.2
TRRP4AP
PPP1R158
HGNC Alias nameprotein phosphatase 1, regulatory subunit 158
HGNC Previous nameC20orf188
HGNC Previous namechromosome 20 open reading frame 188
 transient receptor potential cation channel, subfamily C, member 4 associated protein
LocusID (NCBI) 26133
Atlas_Id 54726
Location 20q11.22  [Link to chromosome band 20q11]
Location_base_pair Starts at 35002404 and ends at 35092815 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
TAF1D (11q21) / TRPC4AP (20q11.22)TRPC4AP (20q11.22) / ACSBG2 (19p13.3)TRPC4AP (20q11.22) / LMF2 (22q13.33)
TRPC4AP (20q11.22) / MRPL45 (17q12)TRPC4AP (20q11.22) / RALY (20q11.22)TRPC4AP (20q11.22) / RPRD1B (20q11.23)
TRPC4AP (20q11.22) / SPG20-AS1 (13q13.3)TRPC4AP (20q11.22) / TMEM245 (9q31.3)TRPC4AP (20q11.22) / TOX2 (20q13.12)
TRPC4AP 20q11.22 C9orf5TRPC4AP 20q11.22 / RALY 20q11.22TRPC4AP 20q11.22 SPG20OS
TRPC4AP 20q11.22 / TOX2 20q13.12

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)TRPC4AP   16181
Cards
Entrez_Gene (NCBI)TRPC4AP    transient receptor potential cation channel subfamily C member 4 associated protein
AliasesC20orf188; PPP1R158; TRRP4AP; TRUSS
GeneCards (Weizmann)TRPC4AP
Ensembl hg19 (Hinxton)ENSG00000100991 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000100991 [Gene_View]  ENSG00000100991 [Sequence]  chr20:35002404-35092815 [Contig_View]  TRPC4AP [Vega]
ICGC DataPortalENSG00000100991
TCGA cBioPortalTRPC4AP
AceView (NCBI)TRPC4AP
Genatlas (Paris)TRPC4AP
SOURCE (Princeton)TRPC4AP
Genetics Home Reference (NIH)TRPC4AP
Genomic and cartography
GoldenPath hg38 (UCSC)TRPC4AP  -     chr20:35002404-35092815 -  20q11.22   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TRPC4AP  -     20q11.22   [Description]    (hg19-Feb_2009)
GoldenPathTRPC4AP - 20q11.22 [CytoView hg19]  TRPC4AP - 20q11.22 [CytoView hg38]
ImmunoBaseENSG00000100991
Genome Data Viewer NCBITRPC4AP [Mapview hg19]  
OMIM608430   
Gene and transcription
Genbank (Entrez)AF055022 AK074106 AK298958 AK301368 AK303476
RefSeq transcript (Entrez)NM_015638 NM_199368
Consensus coding sequences : CCDS (NCBI)TRPC4AP
Gene ExpressionTRPC4AP [ NCBI-GEO ]   TRPC4AP [ EBI - ARRAY_EXPRESS ]   TRPC4AP [ SEEK ]   TRPC4AP [ MEM ]
Gene Expression Viewer (FireBrowse)TRPC4AP [ Firebrowse - Broad ]
GenevisibleExpression of TRPC4AP in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)26133
GTEX Portal (Tissue expression)TRPC4AP
Human Protein AtlasENSG00000100991-TRPC4AP [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8TEL6   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8TEL6  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8TEL6
PhosPhoSitePlusQ8TEL6
Domains : Interpro (EBI)ARM-type_fold    TRPC4AP   
Domain families : Pfam (Sanger)DUF3689 (PF12463)   
Domain families : Pfam (NCBI)pfam12463   
Conserved Domain (NCBI)TRPC4AP
SuperfamilyQ8TEL6
AlphaFold pdb e-kbQ8TEL6   
Human Protein Atlas [tissue]ENSG00000100991-TRPC4AP [tissue]
HPRD09238
Protein Interaction databases
DIP (DOE-UCLA)Q8TEL6
IntAct (EBI)Q8TEL6
BioGRIDTRPC4AP
STRING (EMBL)TRPC4AP
ZODIACTRPC4AP
Ontologies - Pathways
QuickGOQ8TEL6
Ontology : AmiGOprotein binding  plasma membrane  ubiquitin-dependent protein catabolic process  ubiquitin-dependent protein catabolic process  protein ubiquitination  protein ubiquitination  phosphatase binding  phosphatase binding  Cul4A-RING E3 ubiquitin ligase complex  Cul4A-RING E3 ubiquitin ligase complex  hair follicle maturation  calcium ion transmembrane transport  
Ontology : EGO-EBIprotein binding  plasma membrane  ubiquitin-dependent protein catabolic process  ubiquitin-dependent protein catabolic process  protein ubiquitination  protein ubiquitination  phosphatase binding  phosphatase binding  Cul4A-RING E3 ubiquitin ligase complex  Cul4A-RING E3 ubiquitin ligase complex  hair follicle maturation  calcium ion transmembrane transport  
NDEx NetworkTRPC4AP
Atlas of Cancer Signalling NetworkTRPC4AP
Wikipedia pathwaysTRPC4AP
Orthology - Evolution
OrthoDB26133
GeneTree (enSembl)ENSG00000100991
Phylogenetic Trees/Animal Genes : TreeFamTRPC4AP
Homologs : HomoloGeneTRPC4AP
Homology/Alignments : Family Browser (UCSC)TRPC4AP
Gene fusions - Rearrangements
Fusion : MitelmanTRPC4AP/MRPL45 [20q11.22/17q12]  
Fusion : MitelmanTRPC4AP/RALY [20q11.22/20q11.22]  
Fusion : MitelmanTRPC4AP/SPG20-AS1 [20q11.22/13q13.3]  
Fusion : MitelmanTRPC4AP/TMEM245 [20q11.22/9q31.3]  
Fusion : MitelmanTRPC4AP/TOX2 [20q11.22/20q13.12]  
Fusion : QuiverTRPC4AP
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTRPC4AP [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TRPC4AP
dbVarTRPC4AP
ClinVarTRPC4AP
MonarchTRPC4AP
1000_GenomesTRPC4AP 
Exome Variant ServerTRPC4AP
GNOMAD BrowserENSG00000100991
Varsome BrowserTRPC4AP
ACMGTRPC4AP variants
VarityQ8TEL6
Genomic Variants (DGV)TRPC4AP [DGVbeta]
DECIPHERTRPC4AP [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTRPC4AP 
Mutations
ICGC Data PortalTRPC4AP 
TCGA Data PortalTRPC4AP 
Broad Tumor PortalTRPC4AP
OASIS PortalTRPC4AP [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTRPC4AP  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DTRPC4AP
Mutations and Diseases : HGMDTRPC4AP
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaTRPC4AP
DgiDB (Drug Gene Interaction Database)TRPC4AP
DoCM (Curated mutations)TRPC4AP
CIViC (Clinical Interpretations of Variants in Cancer)TRPC4AP
Cancer3DTRPC4AP
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM608430   
Orphanet
DisGeNETTRPC4AP
MedgenTRPC4AP
Genetic Testing Registry TRPC4AP
NextProtQ8TEL6 [Medical]
GENETestsTRPC4AP
Target ValidationTRPC4AP
Huge Navigator TRPC4AP [HugePedia]
ClinGenTRPC4AP
Clinical trials, drugs, therapy
MyCancerGenomeTRPC4AP
Protein Interactions : CTDTRPC4AP
Pharm GKB GenePA25730
PharosQ8TEL6
Clinical trialTRPC4AP
Miscellaneous
canSAR (ICR)TRPC4AP
HarmonizomeTRPC4AP
DataMed IndexTRPC4AP
Probes
Litterature
PubMed41 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXTRPC4AP
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 15:36:30 CEST 2021

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