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TRPM5 (transient receptor potential cation channel subfamily M member 5)

Identity

Alias (NCBI)LTRPC5
MTR1
HGNC (Hugo) TRPM5
HGNC Alias symbLTRPC5
MTR1
HGNC Previous nametransient receptor potential cation channel, subfamily M, member 5
LocusID (NCBI) 29850
Atlas_Id 42708
Location 11p15.5  [Link to chromosome band 11p15]
Location_base_pair Starts at 2404516 and ends at 2423045 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

 

Nomenclature
HGNC (Hugo)TRPM5   14323
Cards
Entrez_Gene (NCBI)TRPM5    transient receptor potential cation channel subfamily M member 5
AliasesLTRPC5; MTR1
GeneCards (Weizmann)TRPM5
Ensembl hg19 (Hinxton)ENSG00000070985 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000070985 [Gene_View]  ENSG00000070985 [Sequence]  chr11:2404516-2423045 [Contig_View]  TRPM5 [Vega]
ICGC DataPortalENSG00000070985
TCGA cBioPortalTRPM5
AceView (NCBI)TRPM5
Genatlas (Paris)TRPM5
SOURCE (Princeton)TRPM5
Genetics Home Reference (NIH)TRPM5
Genomic and cartography
GoldenPath hg38 (UCSC)TRPM5  -     chr11:2404516-2423045 -  11p15.5   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TRPM5  -     11p15.5   [Description]    (hg19-Feb_2009)
GoldenPathTRPM5 - 11p15.5 [CytoView hg19]  TRPM5 - 11p15.5 [CytoView hg38]
ImmunoBaseENSG00000070985
Genome Data Viewer NCBITRPM5 [Mapview hg19]  
OMIM604600   
Gene and transcription
Genbank (Entrez)AF177473 AJ270996 BC093787 BC093789 BC143351
RefSeq transcript (Entrez)NM_014555
Consensus coding sequences : CCDS (NCBI)TRPM5
Gene ExpressionTRPM5 [ NCBI-GEO ]   TRPM5 [ EBI - ARRAY_EXPRESS ]   TRPM5 [ SEEK ]   TRPM5 [ MEM ]
Gene Expression Viewer (FireBrowse)TRPM5 [ Firebrowse - Broad ]
GenevisibleExpression of TRPM5 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)29850
GTEX Portal (Tissue expression)TRPM5
Human Protein AtlasENSG00000070985-TRPM5 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9NZQ8   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9NZQ8  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9NZQ8
PhosPhoSitePlusQ9NZQ8
Domains : Interpro (EBI)Ion_trans_dom    TRPM5    TRPM_SLOG   
Domain families : Pfam (Sanger)Ion_trans (PF00520)    LSDAT_euk (PF18139)   
Domain families : Pfam (NCBI)pfam00520    pfam18139   
Conserved Domain (NCBI)TRPM5
SuperfamilyQ9NZQ8
AlphaFold pdb e-kbQ9NZQ8   
Human Protein Atlas [tissue]ENSG00000070985-TRPM5 [tissue]
HPRD16064
Protein Interaction databases
DIP (DOE-UCLA)Q9NZQ8
IntAct (EBI)Q9NZQ8
BioGRIDTRPM5
STRING (EMBL)TRPM5
ZODIACTRPM5
Ontologies - Pathways
QuickGOQ9NZQ8
Ontology : AmiGOion channel activity  calcium activated cation channel activity  voltage-gated ion channel activity  cation channel activity  potassium channel activity  sodium channel activity  protein binding  plasma membrane  integral component of plasma membrane  integral component of membrane  calcium-mediated signaling  dendrite  regulation of ion transmembrane transport  sodium ion transmembrane transport  neuronal cell body  sensory perception of taste  calcium ion transmembrane transport  calcium ion transmembrane transport  potassium ion transmembrane transport  cation transmembrane transport  ligand-gated calcium channel activity  
Ontology : EGO-EBIion channel activity  calcium activated cation channel activity  voltage-gated ion channel activity  cation channel activity  potassium channel activity  sodium channel activity  protein binding  plasma membrane  integral component of plasma membrane  integral component of membrane  calcium-mediated signaling  dendrite  regulation of ion transmembrane transport  sodium ion transmembrane transport  neuronal cell body  sensory perception of taste  calcium ion transmembrane transport  calcium ion transmembrane transport  potassium ion transmembrane transport  cation transmembrane transport  ligand-gated calcium channel activity  
Pathways : KEGGTaste transduction   
NDEx NetworkTRPM5
Atlas of Cancer Signalling NetworkTRPM5
Wikipedia pathwaysTRPM5
Orthology - Evolution
OrthoDB29850
GeneTree (enSembl)ENSG00000070985
Phylogenetic Trees/Animal Genes : TreeFamTRPM5
Homologs : HomoloGeneTRPM5
Homology/Alignments : Family Browser (UCSC)TRPM5
Gene fusions - Rearrangements
Fusion : QuiverTRPM5
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTRPM5 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TRPM5
dbVarTRPM5
ClinVarTRPM5
MonarchTRPM5
1000_GenomesTRPM5 
Exome Variant ServerTRPM5
GNOMAD BrowserENSG00000070985
Varsome BrowserTRPM5
ACMGTRPM5 variants
VarityQ9NZQ8
Genomic Variants (DGV)TRPM5 [DGVbeta]
DECIPHERTRPM5 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTRPM5 
Mutations
ICGC Data PortalTRPM5 
TCGA Data PortalTRPM5 
Broad Tumor PortalTRPM5
OASIS PortalTRPM5 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTRPM5  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DTRPM5
Mutations and Diseases : HGMDTRPM5
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaTRPM5
DgiDB (Drug Gene Interaction Database)TRPM5
DoCM (Curated mutations)TRPM5
CIViC (Clinical Interpretations of Variants in Cancer)TRPM5
Cancer3DTRPM5
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM604600   
Orphanet
DisGeNETTRPM5
MedgenTRPM5
Genetic Testing Registry TRPM5
NextProtQ9NZQ8 [Medical]
GENETestsTRPM5
Target ValidationTRPM5
Huge Navigator TRPM5 [HugePedia]
ClinGenTRPM5
Clinical trials, drugs, therapy
MyCancerGenomeTRPM5
Protein Interactions : CTDTRPM5
Pharm GKB GenePA37869
PharosQ9NZQ8
Clinical trialTRPM5
Miscellaneous
canSAR (ICR)TRPM5
HarmonizomeTRPM5
DataMed IndexTRPM5
Probes
Litterature
PubMed27 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXTRPM5
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 15:36:32 CEST 2021
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