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TRPM5 (transient receptor potential cation channel subfamily M member 5)

Identity

Alias_namestransient receptor potential cation channel
Alias_symbol (synonym)LTRPC5
MTR1
Other alias
HGNC (Hugo) TRPM5
LocusID (NCBI) 29850
Atlas_Id 42708
Location 11p15.5  [Link to chromosome band 11p15]
Location_base_pair Starts at 2404516 and ends at 2423045 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)TRPM5   14323
Cards
Entrez_Gene (NCBI)TRPM5  29850  transient receptor potential cation channel subfamily M member 5
AliasesLTRPC5; MTR1
GeneCards (Weizmann)TRPM5
Ensembl hg19 (Hinxton)ENSG00000070985 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000070985 [Gene_View]  ENSG00000070985 [Sequence]  chr11:2404516-2423045 [Contig_View]  TRPM5 [Vega]
ICGC DataPortalENSG00000070985
TCGA cBioPortalTRPM5
AceView (NCBI)TRPM5
Genatlas (Paris)TRPM5
WikiGenes29850
SOURCE (Princeton)TRPM5
Genetics Home Reference (NIH)TRPM5
Genomic and cartography
GoldenPath hg38 (UCSC)TRPM5  -     chr11:2404516-2423045 -  11p15.5   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TRPM5  -     11p15.5   [Description]    (hg19-Feb_2009)
EnsemblTRPM5 - 11p15.5 [CytoView hg19]  TRPM5 - 11p15.5 [CytoView hg38]
Mapping of homologs : NCBITRPM5 [Mapview hg19]  TRPM5 [Mapview hg38]
OMIM604600   
Gene and transcription
Genbank (Entrez)AF177473 AJ270996 BC093787 BC093789 BC143351
RefSeq transcript (Entrez)NM_014555
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)TRPM5
Cluster EST : UnigeneHs.272287 [ NCBI ]
CGAP (NCI)Hs.272287
Alternative Splicing GalleryENSG00000070985
Gene ExpressionTRPM5 [ NCBI-GEO ]   TRPM5 [ EBI - ARRAY_EXPRESS ]   TRPM5 [ SEEK ]   TRPM5 [ MEM ]
Gene Expression Viewer (FireBrowse)TRPM5 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)29850
GTEX Portal (Tissue expression)TRPM5
Human Protein AtlasENSG00000070985-TRPM5 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9NZQ8   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9NZQ8  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9NZQ8
Splice isoforms : SwissVarQ9NZQ8
PhosPhoSitePlusQ9NZQ8
Domains : Interpro (EBI)Ion_trans_dom    TRPM5   
Domain families : Pfam (Sanger)Ion_trans (PF00520)   
Domain families : Pfam (NCBI)pfam00520   
Conserved Domain (NCBI)TRPM5
DMDM Disease mutations29850
Blocks (Seattle)TRPM5
SuperfamilyQ9NZQ8
Human Protein Atlas [tissue]ENSG00000070985-TRPM5 [tissue]
Peptide AtlasQ9NZQ8
HPRD16064
IPIIPI00942704   IPI00329503   IPI00889744   IPI00981218   IPI00976379   
Protein Interaction databases
DIP (DOE-UCLA)Q9NZQ8
IntAct (EBI)Q9NZQ8
FunCoupENSG00000070985
BioGRIDTRPM5
STRING (EMBL)TRPM5
ZODIACTRPM5
Ontologies - Pathways
QuickGOQ9NZQ8
Ontology : AmiGOion channel activity  calcium activated cation channel activity  voltage-gated ion channel activity  potassium channel activity  sodium channel activity  plasma membrane  integral component of membrane  dendrite  regulation of ion transmembrane transport  sodium ion transmembrane transport  neuronal cell body  sensory perception of taste  calcium ion transmembrane transport  potassium ion transmembrane transport  
Ontology : EGO-EBIion channel activity  calcium activated cation channel activity  voltage-gated ion channel activity  potassium channel activity  sodium channel activity  plasma membrane  integral component of membrane  dendrite  regulation of ion transmembrane transport  sodium ion transmembrane transport  neuronal cell body  sensory perception of taste  calcium ion transmembrane transport  potassium ion transmembrane transport  
Pathways : KEGGTaste transduction   
NDEx NetworkTRPM5
Atlas of Cancer Signalling NetworkTRPM5
Wikipedia pathwaysTRPM5
Orthology - Evolution
OrthoDB29850
GeneTree (enSembl)ENSG00000070985
Phylogenetic Trees/Animal Genes : TreeFamTRPM5
HOVERGENQ9NZQ8
HOGENOMQ9NZQ8
Homologs : HomoloGeneTRPM5
Homology/Alignments : Family Browser (UCSC)TRPM5
Gene fusions - Rearrangements
Fusion : QuiverTRPM5
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTRPM5 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TRPM5
dbVarTRPM5
ClinVarTRPM5
1000_GenomesTRPM5 
Exome Variant ServerTRPM5
ExAC (Exome Aggregation Consortium)ENSG00000070985
GNOMAD BrowserENSG00000070985
Genetic variants : HAPMAP29850
Genomic Variants (DGV)TRPM5 [DGVbeta]
DECIPHERTRPM5 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTRPM5 
Mutations
ICGC Data PortalTRPM5 
TCGA Data PortalTRPM5 
Broad Tumor PortalTRPM5
OASIS PortalTRPM5 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTRPM5  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDTRPM5
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch TRPM5
DgiDB (Drug Gene Interaction Database)TRPM5
DoCM (Curated mutations)TRPM5 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)TRPM5 (select a term)
intoGenTRPM5
Cancer3DTRPM5(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM604600   
Orphanet
DisGeNETTRPM5
MedgenTRPM5
Genetic Testing Registry TRPM5
NextProtQ9NZQ8 [Medical]
TSGene29850
GENETestsTRPM5
Target ValidationTRPM5
Huge Navigator TRPM5 [HugePedia]
snp3D : Map Gene to Disease29850
BioCentury BCIQTRPM5
ClinGenTRPM5
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD29850
Chemical/Pharm GKB GenePA37869
Clinical trialTRPM5
Miscellaneous
canSAR (ICR)TRPM5 (select the gene name)
Probes
Litterature
PubMed22 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTRPM5
EVEXTRPM5
GoPubMedTRPM5
iHOPTRPM5
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Fri Jun 22 16:55:32 CEST 2018
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