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TRPM7 (transient receptor potential cation channel subfamily M member 7)

Identity

Alias (NCBI)ALSPDC
CHAK
CHAK1
LTRPC7
LTrpC-7
TRP-PLIK
HGNC (Hugo) TRPM7
HGNC Alias symbCHAK1
LTRPC7
TRP-PLIK
HGNC Previous nametransient receptor potential cation channel, subfamily M, member 7
LocusID (NCBI) 54822
Atlas_Id 43545
Location 15q21.2  [Link to chromosome band 15q21]
Location_base_pair Starts at 50557159 and ends at 50686797 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
TRPM7 (15q21.2) / FAM227B (15q21.2)TRPM7 (15q21.2) / TMEM104 (17q25.1)USP8 (15q21.2) / TRPM7 (15q21.2)
TRPM7 15q21.2 C15orf33TRPM7 15q21.2 / TMEM104 17q25.1

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)TRPM7   17994
LRG (Locus Reference Genomic)LRG_1192
Cards
Entrez_Gene (NCBI)TRPM7    transient receptor potential cation channel subfamily M member 7
AliasesALSPDC; CHAK; CHAK1; LTRPC7; 
LTrpC-7; TRP-PLIK
GeneCards (Weizmann)TRPM7
Ensembl hg19 (Hinxton)ENSG00000092439 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000092439 [Gene_View]  ENSG00000092439 [Sequence]  chr15:50557159-50686797 [Contig_View]  TRPM7 [Vega]
ICGC DataPortalENSG00000092439
TCGA cBioPortalTRPM7
AceView (NCBI)TRPM7
Genatlas (Paris)TRPM7
SOURCE (Princeton)TRPM7
Genetics Home Reference (NIH)TRPM7
Genomic and cartography
GoldenPath hg38 (UCSC)TRPM7  -     chr15:50557159-50686797 -  15q21.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TRPM7  -     15q21.2   [Description]    (hg19-Feb_2009)
GoldenPathTRPM7 - 15q21.2 [CytoView hg19]  TRPM7 - 15q21.2 [CytoView hg38]
ImmunoBaseENSG00000092439
Genome Data Viewer NCBITRPM7 [Mapview hg19]  
OMIM105500   605692   
Gene and transcription
Genbank (Entrez)AF346629 AK000124 AK075193 AK098584 AK172800
RefSeq transcript (Entrez)NM_001301212 NM_017672
Consensus coding sequences : CCDS (NCBI)TRPM7
Gene ExpressionTRPM7 [ NCBI-GEO ]   TRPM7 [ EBI - ARRAY_EXPRESS ]   TRPM7 [ SEEK ]   TRPM7 [ MEM ]
Gene Expression Viewer (FireBrowse)TRPM7 [ Firebrowse - Broad ]
GenevisibleExpression of TRPM7 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)54822
GTEX Portal (Tissue expression)TRPM7
Human Protein AtlasENSG00000092439-TRPM7 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96QT4   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ96QT4  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ96QT4
Catalytic activity : Enzyme2.7.11.1 [ Enzyme-Expasy ]   2.7.11.12.7.11.1 [ IntEnz-EBI ]   2.7.11.1 [ BRENDA ]   2.7.11.1 [ KEGG ]   [ MEROPS ]
PhosPhoSitePlusQ96QT4
Domaine pattern : Prosite (Expaxy)ALPHA_KINASE (PS51158)   
Domains : Interpro (EBI)Ion_trans_dom    Kinase-like_dom_sf    MHCK_EF2_kinase    TRPM7    TRPM_SLOG    TRPM_tetra    TRPM_tetra_sf   
Domain families : Pfam (Sanger)Alpha_kinase (PF02816)    Ion_trans (PF00520)    LSDAT_euk (PF18139)    TRPM_tetra (PF16519)   
Domain families : Pfam (NCBI)pfam02816    pfam00520    pfam18139    pfam16519   
Domain families : Smart (EMBL)Alpha_kinase (SM00811)  
Conserved Domain (NCBI)TRPM7
SuperfamilyQ96QT4
AlphaFold pdb e-kbQ96QT4   
Human Protein Atlas [tissue]ENSG00000092439-TRPM7 [tissue]
HPRD10418
Protein Interaction databases
DIP (DOE-UCLA)Q96QT4
IntAct (EBI)Q96QT4
BioGRIDTRPM7
STRING (EMBL)TRPM7
ZODIACTRPM7
Ontologies - Pathways
QuickGOQ96QT4
Ontology : AmiGOruffle  actin binding  cation channel activity  calcium channel activity  ATP binding  plasma membrane  integral component of plasma membrane  calcium ion transport  cellular magnesium ion homeostasis  calcium-dependent cell-matrix adhesion  myosin binding  actomyosin structure organization  protein autophosphorylation  metal ion binding  protein tetramerization  necroptotic process  calcium ion transmembrane transport  divalent inorganic cation homeostasis  cation transmembrane transport  protein serine kinase activity  protein threonine kinase activity  
Ontology : EGO-EBIruffle  actin binding  cation channel activity  calcium channel activity  ATP binding  plasma membrane  integral component of plasma membrane  calcium ion transport  cellular magnesium ion homeostasis  calcium-dependent cell-matrix adhesion  myosin binding  actomyosin structure organization  protein autophosphorylation  metal ion binding  protein tetramerization  necroptotic process  calcium ion transmembrane transport  divalent inorganic cation homeostasis  cation transmembrane transport  protein serine kinase activity  protein threonine kinase activity  
Pathways : KEGGMineral absorption   
NDEx NetworkTRPM7
Atlas of Cancer Signalling NetworkTRPM7
Wikipedia pathwaysTRPM7
Orthology - Evolution
OrthoDB54822
GeneTree (enSembl)ENSG00000092439
Phylogenetic Trees/Animal Genes : TreeFamTRPM7
Homologs : HomoloGeneTRPM7
Homology/Alignments : Family Browser (UCSC)TRPM7
Gene fusions - Rearrangements
Fusion : MitelmanTRPM7/FAM227B [15q21.2/15q21.2]  
Fusion : MitelmanTRPM7/TMEM104 [15q21.2/17q25.1]  
Fusion : QuiverTRPM7
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTRPM7 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TRPM7
dbVarTRPM7
ClinVarTRPM7
MonarchTRPM7
1000_GenomesTRPM7 
Exome Variant ServerTRPM7
GNOMAD BrowserENSG00000092439
Varsome BrowserTRPM7
ACMGTRPM7 variants
VarityQ96QT4
Genomic Variants (DGV)TRPM7 [DGVbeta]
DECIPHERTRPM7 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTRPM7 
Mutations
ICGC Data PortalTRPM7 
TCGA Data PortalTRPM7 
Broad Tumor PortalTRPM7
OASIS PortalTRPM7 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTRPM7  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DTRPM7
Mutations and Diseases : HGMDTRPM7
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaTRPM7
DgiDB (Drug Gene Interaction Database)TRPM7
DoCM (Curated mutations)TRPM7
CIViC (Clinical Interpretations of Variants in Cancer)TRPM7
Cancer3DTRPM7
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM105500    605692   
Orphanet11922   
DisGeNETTRPM7
MedgenTRPM7
Genetic Testing Registry TRPM7
NextProtQ96QT4 [Medical]
GENETestsTRPM7
Target ValidationTRPM7
Huge Navigator TRPM7 [HugePedia]
ClinGenTRPM7
Clinical trials, drugs, therapy
MyCancerGenomeTRPM7
Protein Interactions : CTDTRPM7
Pharm GKB GenePA38273
PharosQ96QT4
Clinical trialTRPM7
Miscellaneous
canSAR (ICR)TRPM7
HarmonizomeTRPM7
DataMed IndexTRPM7
Probes
Litterature
PubMed188 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXTRPM7
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 15:36:32 CEST 2021

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