Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

TRRAP (transformation/transcription domain associated protein)

Identity

Alias_namestransformation/transcription domain-associated protein
Alias_symbol (synonym)TR-AP
PAF400
Tra1
Other aliasPAF350/400
STAF40
HGNC (Hugo) TRRAP
LocusID (NCBI) 8295
Atlas_Id 42710
Location 7q22.1  [Link to chromosome band 7q22]
Location_base_pair Starts at 98476113 and ends at 98610866 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
ARPC1A (7q22.1) / TRRAP (7q22.1)TRRAP (7q22.1) / ANKRD12 (18p11.22)TRRAP (7q22.1) / BTBD9 (6p21.2)
TRRAP (7q22.1) / FBLIM1 (1p36.21)TRRAP (7q22.1) / PRKAR2B (7q22.3)ARPC1A 7q22.1 / TRRAP 7q22.1
TRRAP 7q22.1 / PRKAR2B 7q22.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)TRRAP   12347
Cards
Entrez_Gene (NCBI)TRRAP  8295  transformation/transcription domain associated protein
AliasesPAF350/400; PAF400; STAF40; TR-AP; 
Tra1
GeneCards (Weizmann)TRRAP
Ensembl hg19 (Hinxton)ENSG00000196367 [Gene_View]  chr7:98476113-98610866 [Contig_View]  TRRAP [Vega]
Ensembl hg38 (Hinxton)ENSG00000196367 [Gene_View]  chr7:98476113-98610866 [Contig_View]  TRRAP [Vega]
ICGC DataPortalENSG00000196367
TCGA cBioPortalTRRAP
AceView (NCBI)TRRAP
Genatlas (Paris)TRRAP
WikiGenes8295
SOURCE (Princeton)TRRAP
Genetics Home Reference (NIH)TRRAP
Genomic and cartography
GoldenPath hg19 (UCSC)TRRAP  -     chr7:98476113-98610866 +  7q22.1   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)TRRAP  -     7q22.1   [Description]    (hg38-Dec_2013)
EnsemblTRRAP - 7q22.1 [CytoView hg19]  TRRAP - 7q22.1 [CytoView hg38]
Mapping of homologs : NCBITRRAP [Mapview hg19]  TRRAP [Mapview hg38]
OMIM603015   
Gene and transcription
Genbank (Entrez)AB209489 AF076974 AF110377 AL050077 BC032759
RefSeq transcript (Entrez)NM_001244580 NM_003496
RefSeq genomic (Entrez)NC_000007 NC_018918 NG_030010 NT_007933 NW_004929332
Consensus coding sequences : CCDS (NCBI)TRRAP
Cluster EST : UnigeneHs.203952 [ NCBI ]
CGAP (NCI)Hs.203952
Alternative Splicing GalleryENSG00000196367
Gene ExpressionTRRAP [ NCBI-GEO ]   TRRAP [ EBI - ARRAY_EXPRESS ]   TRRAP [ SEEK ]   TRRAP [ MEM ]
Gene Expression Viewer (FireBrowse)TRRAP [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)8295
GTEX Portal (Tissue expression)TRRAP
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9Y4A5   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9Y4A5  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9Y4A5
Splice isoforms : SwissVarQ9Y4A5
PhosPhoSitePlusQ9Y4A5
Domaine pattern : Prosite (Expaxy)FAT (PS51189)    FATC (PS51190)    PI3_4_KINASE_3 (PS50290)   
Domains : Interpro (EBI)ARM-like    ARM-type_fold    FATC_dom    Kinase-like_dom    PI3/4_kinase_cat_dom    PIK-rel_kinase_FAT    PIK_FAT    TPR-like_helical_dom   
Domain families : Pfam (Sanger)FAT (PF02259)    PI3_PI4_kinase (PF00454)   
Domain families : Pfam (NCBI)pfam02259    pfam00454   
Domain families : Smart (EMBL)PI3Kc (SM00146)  
Conserved Domain (NCBI)TRRAP
DMDM Disease mutations8295
Blocks (Seattle)TRRAP
SuperfamilyQ9Y4A5
Human Protein AtlasENSG00000196367
Peptide AtlasQ9Y4A5
HPRD04310
IPIIPI00069084   IPI00879277   IPI00926412   IPI00925034   IPI00925559   
Protein Interaction databases
DIP (DOE-UCLA)Q9Y4A5
IntAct (EBI)Q9Y4A5
FunCoupENSG00000196367
BioGRIDTRRAP
STRING (EMBL)TRRAP
ZODIACTRRAP
Ontologies - Pathways
QuickGOQ9Y4A5
Ontology : AmiGOPCAF complex  Swr1 complex  transcription cofactor activity  protein binding  nucleus  nucleoplasm  nucleoplasm  Golgi apparatus  DNA repair  transcription, DNA-templated  regulation of transcription, DNA-templated  kinase activity  phosphorylation  histone acetylation  histone deubiquitination  phosphotransferase activity, alcohol group as acceptor  STAGA complex  transcription factor TFTC complex  NuA4 histone acetyltransferase complex  histone H4 acetylation  histone H2A acetylation  beta-catenin-TCF complex assembly  
Ontology : EGO-EBIPCAF complex  Swr1 complex  transcription cofactor activity  protein binding  nucleus  nucleoplasm  nucleoplasm  Golgi apparatus  DNA repair  transcription, DNA-templated  regulation of transcription, DNA-templated  kinase activity  phosphorylation  histone acetylation  histone deubiquitination  phosphotransferase activity, alcohol group as acceptor  STAGA complex  transcription factor TFTC complex  NuA4 histone acetyltransferase complex  histone H4 acetylation  histone H2A acetylation  beta-catenin-TCF complex assembly  
Pathways : BIOCARTAMulti-step Regulation of Transcription by Pitx2 [Genes]   
Pathways : KEGGHTLV-I infection   
NDEx NetworkTRRAP
Atlas of Cancer Signalling NetworkTRRAP
Wikipedia pathwaysTRRAP
Orthology - Evolution
OrthoDB8295
GeneTree (enSembl)ENSG00000196367
Phylogenetic Trees/Animal Genes : TreeFamTRRAP
HOVERGENQ9Y4A5
HOGENOMQ9Y4A5
Homologs : HomoloGeneTRRAP
Homology/Alignments : Family Browser (UCSC)TRRAP
Gene fusions - Rearrangements
Fusion : MitelmanARPC1A/TRRAP [7q22.1/7q22.1]  [t(7;7)(q22;q22)]  
Fusion : MitelmanTRRAP/PRKAR2B [7q22.1/7q22.3]  [t(7;7)(q22;q22)]  
Fusion: TCGAARPC1A 7q22.1 TRRAP 7q22.1 PRAD
Fusion: TCGATRRAP 7q22.1 PRKAR2B 7q22.3 BRCA
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTRRAP [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TRRAP
dbVarTRRAP
ClinVarTRRAP
1000_GenomesTRRAP 
Exome Variant ServerTRRAP
ExAC (Exome Aggregation Consortium)TRRAP (select the gene name)
Genetic variants : HAPMAP8295
Genomic Variants (DGV)TRRAP [DGVbeta]
DECIPHER (Syndromes)7:98476113-98610866  ENSG00000196367
CONAN: Copy Number AnalysisTRRAP 
Mutations
ICGC Data PortalTRRAP 
TCGA Data PortalTRRAP 
Broad Tumor PortalTRRAP
OASIS PortalTRRAP [ Somatic mutations - Copy number]
Cancer Gene: CensusTRRAP 
Somatic Mutations in Cancer : COSMICTRRAP  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDTRRAP
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch TRRAP
DgiDB (Drug Gene Interaction Database)TRRAP
DoCM (Curated mutations)TRRAP (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)TRRAP (select a term)
intoGenTRRAP
Cancer3DTRRAP(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM603015   
Orphanet
MedgenTRRAP
Genetic Testing Registry TRRAP
NextProtQ9Y4A5 [Medical]
TSGene8295
GENETestsTRRAP
Huge Navigator TRRAP [HugePedia]
snp3D : Map Gene to Disease8295
BioCentury BCIQTRRAP
ClinGenTRRAP
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD8295
Chemical/Pharm GKB GenePA37020
Clinical trialTRRAP
Miscellaneous
canSAR (ICR)TRRAP (select the gene name)
Probes
Litterature
PubMed107 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTRRAP
EVEXTRRAP
GoPubMedTRRAP
iHOPTRRAP
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Mar 14 13:32:31 CET 2017

Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.