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TRUB1 (TruB pseudouridine synthase family member 1)

Identity

Alias (NCBI)PUS4
HGNC (Hugo) TRUB1
HGNC Alias symbPUS4
HGNC Alias nameprobable tRNA pseudouridine synthase 1
HGNC Previous nameTruB pseudouridine (psi) synthase homolog 1 (E. coli)
 TruB pseudouridine (psi) synthase family member 1
LocusID (NCBI) 142940
Atlas_Id 75215
Location 10q25.3  [Link to chromosome band 10q25]
Location_base_pair Starts at 114938195 and ends at 114977676 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
TAF1D (11q21) / TRUB1 (10q25.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)TRUB1   16060
Cards
Entrez_Gene (NCBI)TRUB1    TruB pseudouridine synthase family member 1
AliasesPUS4
GeneCards (Weizmann)TRUB1
Ensembl hg19 (Hinxton)ENSG00000165832 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000165832 [Gene_View]  ENSG00000165832 [Sequence]  chr10:114938195-114977676 [Contig_View]  TRUB1 [Vega]
ICGC DataPortalENSG00000165832
TCGA cBioPortalTRUB1
AceView (NCBI)TRUB1
Genatlas (Paris)TRUB1
SOURCE (Princeton)TRUB1
Genetics Home Reference (NIH)TRUB1
Genomic and cartography
GoldenPath hg38 (UCSC)TRUB1  -     chr10:114938195-114977676 +  10q25.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TRUB1  -     10q25.3   [Description]    (hg19-Feb_2009)
GoldenPathTRUB1 - 10q25.3 [CytoView hg19]  TRUB1 - 10q25.3 [CytoView hg38]
ImmunoBaseENSG00000165832
Genome Data Viewer NCBITRUB1 [Mapview hg19]  
OMIM610726   
Gene and transcription
Genbank (Entrez)AF448144 AK026721 AK125554 AK223567 AK302800
RefSeq transcript (Entrez)NM_139169
Consensus coding sequences : CCDS (NCBI)TRUB1
Gene ExpressionTRUB1 [ NCBI-GEO ]   TRUB1 [ EBI - ARRAY_EXPRESS ]   TRUB1 [ SEEK ]   TRUB1 [ MEM ]
Gene Expression Viewer (FireBrowse)TRUB1 [ Firebrowse - Broad ]
GenevisibleExpression of TRUB1 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)142940
GTEX Portal (Tissue expression)TRUB1
Human Protein AtlasENSG00000165832-TRUB1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8WWH5   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8WWH5  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8WWH5
PhosPhoSitePlusQ8WWH5
Domains : Interpro (EBI)PsdUridine_synth_cat_dom_sf    PsdUridine_synth_N    tRNA_psdUridine_synth_TruB   
Domain families : Pfam (Sanger)TruB_N (PF01509)   
Domain families : Pfam (NCBI)pfam01509   
Conserved Domain (NCBI)TRUB1
SuperfamilyQ8WWH5
AlphaFold pdb e-kbQ8WWH5   
Human Protein Atlas [tissue]ENSG00000165832-TRUB1 [tissue]
HPRD18229
Protein Interaction databases
DIP (DOE-UCLA)Q8WWH5
IntAct (EBI)Q8WWH5
BioGRIDTRUB1
STRING (EMBL)TRUB1
ZODIACTRUB1
Ontologies - Pathways
QuickGOQ8WWH5
Ontology : AmiGORNA binding  nucleus  mitochondrion  cytosol  tRNA modification  pseudouridine synthase activity  pseudouridine synthase activity  mRNA pseudouridine synthesis  mRNA pseudouridine synthesis  
Ontology : EGO-EBIRNA binding  nucleus  mitochondrion  cytosol  tRNA modification  pseudouridine synthase activity  pseudouridine synthase activity  mRNA pseudouridine synthesis  mRNA pseudouridine synthesis  
NDEx NetworkTRUB1
Atlas of Cancer Signalling NetworkTRUB1
Wikipedia pathwaysTRUB1
Orthology - Evolution
OrthoDB142940
GeneTree (enSembl)ENSG00000165832
Phylogenetic Trees/Animal Genes : TreeFamTRUB1
Homologs : HomoloGeneTRUB1
Homology/Alignments : Family Browser (UCSC)TRUB1
Gene fusions - Rearrangements
Fusion : QuiverTRUB1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTRUB1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TRUB1
dbVarTRUB1
ClinVarTRUB1
MonarchTRUB1
1000_GenomesTRUB1 
Exome Variant ServerTRUB1
GNOMAD BrowserENSG00000165832
Varsome BrowserTRUB1
ACMGTRUB1 variants
VarityQ8WWH5
Genomic Variants (DGV)TRUB1 [DGVbeta]
DECIPHERTRUB1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTRUB1 
Mutations
ICGC Data PortalTRUB1 
TCGA Data PortalTRUB1 
Broad Tumor PortalTRUB1
OASIS PortalTRUB1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTRUB1  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DTRUB1
Mutations and Diseases : HGMDTRUB1
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaTRUB1
DgiDB (Drug Gene Interaction Database)TRUB1
DoCM (Curated mutations)TRUB1
CIViC (Clinical Interpretations of Variants in Cancer)TRUB1
Cancer3DTRUB1
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM610726   
Orphanet
DisGeNETTRUB1
MedgenTRUB1
Genetic Testing Registry TRUB1
NextProtQ8WWH5 [Medical]
GENETestsTRUB1
Target ValidationTRUB1
Huge Navigator TRUB1 [HugePedia]
ClinGenTRUB1
Clinical trials, drugs, therapy
MyCancerGenomeTRUB1
Protein Interactions : CTDTRUB1
Pharm GKB GenePA38086
PharosQ8WWH5
Clinical trialTRUB1
Miscellaneous
canSAR (ICR)TRUB1
HarmonizomeTRUB1
DataMed IndexTRUB1
Probes
Litterature
PubMed21 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXTRUB1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 16:27:05 CEST 2021

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