TSC22D2 (TSC22 domain family member 2)

2017-04-01  

Identity

HGNC
TSC22D2
LOCATION
3q25.1
LOCUSID
9819
ALIAS
TILZ4a,TILZ4b,TILZ4c
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 9819
MIM: 617724
HGNC: 29095
Ensembl: ENSG00000196428

Variants:

dbSNP: 9819
ClinVar: 9819
TCGA: ENSG00000196428
COSMIC: TSC22D2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000196428ENST00000361875O75157
ENSG00000196428ENST00000466814H0Y865
ENSG00000196428ENST00000480589H7C4U3
ENSG00000196428ENST00000485421H0Y8E9

Expression (GTEx)

0
5
10
15
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
275733522016TSC22D2 interacts with PKM2 and inhibits cell growth in colorectal cancer.21
273379562016Yeast two-hybrid screening identified WDR77 as a novel interacting partner of TSC22D2.19
201492642010Madm (Mlf1 adapter molecule) cooperates with Bunched A to promote growth in Drosophila.11
311254062019TSC22D2 identified as a candidate susceptibility gene of multi-cancer pedigree using genome-wide linkage analysis and whole-exome sequencing.6

Citation

Dessen P

TSC22D2 (TSC22 domain family member 2)

Atlas Genet Cytogenet Oncol Haematol. 2017-04-01

Online version: http://atlasgeneticsoncology.org/gene/56772/tsc22d2