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TSEN15 (TSEN15 tRNA splicing endonuclease subunit)

Identity

Alias_namesC1orf19
chromosome 1 open reading frame 19
tRNA splicing endonuclease 15 homolog (S. cerevisiae)
TSEN15 tRNA splicing endonuclease subunit
Other aliassen15
HGNC (Hugo) TSEN15
LocusID (NCBI) 116461
Atlas_Id 75221
Location 1q25.3  [Link to chromosome band 1q25]
Location_base_pair Starts at 184020785 and ends at 184043344 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
TSEN15 (1q25.3) / ACBD6 (1q25.2)TSEN15 (1q25.3) / ALKBH5 (17p11.2)TSEN15 (1q25.3) / PPP2R2A (8p21.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)TSEN15   16791
Cards
Entrez_Gene (NCBI)TSEN15  116461  TSEN15 tRNA splicing endonuclease subunit
AliasesC1orf19; sen15
GeneCards (Weizmann)TSEN15
Ensembl hg19 (Hinxton)ENSG00000198860 [Gene_View]  chr1:184020785-184043344 [Contig_View]  TSEN15 [Vega]
Ensembl hg38 (Hinxton)ENSG00000198860 [Gene_View]  chr1:184020785-184043344 [Contig_View]  TSEN15 [Vega]
ICGC DataPortalENSG00000198860
TCGA cBioPortalTSEN15
AceView (NCBI)TSEN15
Genatlas (Paris)TSEN15
WikiGenes116461
SOURCE (Princeton)TSEN15
Genetics Home Reference (NIH)TSEN15
Genomic and cartography
GoldenPath hg19 (UCSC)TSEN15  -     chr1:184020785-184043344 +  1q25.3   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)TSEN15  -     1q25.3   [Description]    (hg38-Dec_2013)
EnsemblTSEN15 - 1q25.3 [CytoView hg19]  TSEN15 - 1q25.3 [CytoView hg38]
Mapping of homologs : NCBITSEN15 [Mapview hg19]  TSEN15 [Mapview hg38]
OMIM608756   
Gene and transcription
Genbank (Entrez)AF288394 AK098196 AK296655 AK307241 BC022030
RefSeq transcript (Entrez)NM_001127394 NM_001300764 NM_001300766 NM_052965
RefSeq genomic (Entrez)NC_000001 NC_018912 NT_004487 NW_004929293
Consensus coding sequences : CCDS (NCBI)TSEN15
Cluster EST : UnigeneHs.548197 [ NCBI ]
CGAP (NCI)Hs.548197
Alternative Splicing GalleryENSG00000198860
Gene ExpressionTSEN15 [ NCBI-GEO ]   TSEN15 [ EBI - ARRAY_EXPRESS ]   TSEN15 [ SEEK ]   TSEN15 [ MEM ]
Gene Expression Viewer (FireBrowse)TSEN15 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)116461
GTEX Portal (Tissue expression)TSEN15
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8WW01   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8WW01  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8WW01
Splice isoforms : SwissVarQ8WW01
PhosPhoSitePlusQ8WW01
Domains : Interpro (EBI)tRNA-endonuc_su_Sen15    tRNA_intron_Endonuc_cat-like   
Domain families : Pfam (Sanger)Sen15 (PF09631)   
Domain families : Pfam (NCBI)pfam09631   
Conserved Domain (NCBI)TSEN15
DMDM Disease mutations116461
Blocks (Seattle)TSEN15
PDB (SRS)2GW6   
PDB (PDBSum)2GW6   
PDB (IMB)2GW6   
PDB (RSDB)2GW6   
Structural Biology KnowledgeBase2GW6   
SCOP (Structural Classification of Proteins)2GW6   
CATH (Classification of proteins structures)2GW6   
SuperfamilyQ8WW01
Human Protein AtlasENSG00000198860
Peptide AtlasQ8WW01
HPRD12292
IPIIPI00450071   IPI00642943   IPI00980533   IPI00978645   IPI00828179   
Protein Interaction databases
DIP (DOE-UCLA)Q8WW01
IntAct (EBI)Q8WW01
FunCoupENSG00000198860
BioGRIDTSEN15
STRING (EMBL)TSEN15
ZODIACTSEN15
Ontologies - Pathways
QuickGOQ8WW01
Ontology : AmiGOtRNA-intron endonuclease activity  nucleolus  tRNA splicing, via endonucleolytic cleavage and ligation  mRNA processing  RNA phosphodiester bond hydrolysis, endonucleolytic  
Ontology : EGO-EBItRNA-intron endonuclease activity  nucleolus  tRNA splicing, via endonucleolytic cleavage and ligation  mRNA processing  RNA phosphodiester bond hydrolysis, endonucleolytic  
NDEx NetworkTSEN15
Atlas of Cancer Signalling NetworkTSEN15
Wikipedia pathwaysTSEN15
Orthology - Evolution
OrthoDB116461
GeneTree (enSembl)ENSG00000198860
Phylogenetic Trees/Animal Genes : TreeFamTSEN15
HOVERGENQ8WW01
HOGENOMQ8WW01
Homologs : HomoloGeneTSEN15
Homology/Alignments : Family Browser (UCSC)TSEN15
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTSEN15 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TSEN15
dbVarTSEN15
ClinVarTSEN15
1000_GenomesTSEN15 
Exome Variant ServerTSEN15
ExAC (Exome Aggregation Consortium)TSEN15 (select the gene name)
Genetic variants : HAPMAP116461
Genomic Variants (DGV)TSEN15 [DGVbeta]
DECIPHER (Syndromes)1:184020785-184043344  ENSG00000198860
CONAN: Copy Number AnalysisTSEN15 
Mutations
ICGC Data PortalTSEN15 
TCGA Data PortalTSEN15 
Broad Tumor PortalTSEN15
OASIS PortalTSEN15 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTSEN15  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDTSEN15
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch TSEN15
DgiDB (Drug Gene Interaction Database)TSEN15
DoCM (Curated mutations)TSEN15 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)TSEN15 (select a term)
intoGenTSEN15
Cancer3DTSEN15(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM608756   
Orphanet2334   
MedgenTSEN15
Genetic Testing Registry TSEN15
NextProtQ8WW01 [Medical]
TSGene116461
GENETestsTSEN15
Huge Navigator TSEN15 [HugePedia]
snp3D : Map Gene to Disease116461
BioCentury BCIQTSEN15
ClinGenTSEN15
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD116461
Chemical/Pharm GKB GenePA162407135
Clinical trialTSEN15
Miscellaneous
canSAR (ICR)TSEN15 (select the gene name)
Probes
Litterature
PubMed18 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTSEN15
EVEXTSEN15
GoPubMedTSEN15
iHOPTSEN15
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 12:49:55 CET 2017

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