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TSEN15 (tRNA splicing endonuclease subunit 15)

Identity

Alias (NCBI)C1orf19
PCH2F
sen15
HGNC (Hugo) TSEN15
HGNC Previous nameC1orf19
HGNC Previous namechromosome 1 open reading frame 19
 tRNA splicing endonuclease 15 homolog (S. cerevisiae)
 TSEN15 tRNA splicing endonuclease subunit
LocusID (NCBI) 116461
Atlas_Id 75221
Location 1q25.3  [Link to chromosome band 1q25]
Location_base_pair Starts at 184051730 and ends at 184074210 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
TSEN15 (1q25.3) / ACBD6 (1q25.2)TSEN15 (1q25.3) / ALKBH5 (17p11.2)TSEN15 (1q25.3) / PPP2R2A (8p21.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)TSEN15   16791
Cards
Entrez_Gene (NCBI)TSEN15    tRNA splicing endonuclease subunit 15
AliasesC1orf19; PCH2F; sen15
GeneCards (Weizmann)TSEN15
Ensembl hg19 (Hinxton)ENSG00000198860 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000198860 [Gene_View]  ENSG00000198860 [Sequence]  chr1:184051730-184074210 [Contig_View]  TSEN15 [Vega]
ICGC DataPortalENSG00000198860
TCGA cBioPortalTSEN15
AceView (NCBI)TSEN15
Genatlas (Paris)TSEN15
SOURCE (Princeton)TSEN15
Genetics Home Reference (NIH)TSEN15
Genomic and cartography
GoldenPath hg38 (UCSC)TSEN15  -     chr1:184051730-184074210 +  1q25.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TSEN15  -     1q25.3   [Description]    (hg19-Feb_2009)
GoldenPathTSEN15 - 1q25.3 [CytoView hg19]  TSEN15 - 1q25.3 [CytoView hg38]
ImmunoBaseENSG00000198860
Genome Data Viewer NCBITSEN15 [Mapview hg19]  
OMIM608756   617026   
Gene and transcription
Genbank (Entrez)AF288394 AK098196 AK296655 AK307241 BC022030
RefSeq transcript (Entrez)NM_001127394 NM_001300764 NM_001300766 NM_001363643 NM_052965
Consensus coding sequences : CCDS (NCBI)TSEN15
Gene ExpressionTSEN15 [ NCBI-GEO ]   TSEN15 [ EBI - ARRAY_EXPRESS ]   TSEN15 [ SEEK ]   TSEN15 [ MEM ]
Gene Expression Viewer (FireBrowse)TSEN15 [ Firebrowse - Broad ]
GenevisibleExpression of TSEN15 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)116461
GTEX Portal (Tissue expression)TSEN15
Human Protein AtlasENSG00000198860-TSEN15 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8WW01   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8WW01  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8WW01
PhosPhoSitePlusQ8WW01
Domains : Interpro (EBI)tRNA-endonuc_su_Sen15    tRNA_endonuc-like_dom_sf    tRNA_intron_Endo_cat-like_sf   
Domain families : Pfam (Sanger)Sen15 (PF09631)   
Domain families : Pfam (NCBI)pfam09631   
Conserved Domain (NCBI)TSEN15
PDB (RSDB)2GW6   
PDB Europe2GW6   
PDB (PDBSum)2GW6   
PDB (IMB)2GW6   
Structural Biology KnowledgeBase2GW6   
SCOP (Structural Classification of Proteins)2GW6   
CATH (Classification of proteins structures)2GW6   
SuperfamilyQ8WW01
AlphaFold pdb e-kbQ8WW01   
Human Protein Atlas [tissue]ENSG00000198860-TSEN15 [tissue]
HPRD12292
Protein Interaction databases
DIP (DOE-UCLA)Q8WW01
IntAct (EBI)Q8WW01
BioGRIDTSEN15
STRING (EMBL)TSEN15
ZODIACTSEN15
Ontologies - Pathways
QuickGOQ8WW01
Ontology : AmiGOnucleic acid binding  nuclease activity  protein binding  nucleoplasm  nucleolus  tRNA splicing, via endonucleolytic cleavage and ligation  mRNA processing  nucleic acid phosphodiester bond hydrolysis  
Ontology : EGO-EBInucleic acid binding  nuclease activity  protein binding  nucleoplasm  nucleolus  tRNA splicing, via endonucleolytic cleavage and ligation  mRNA processing  nucleic acid phosphodiester bond hydrolysis  
NDEx NetworkTSEN15
Atlas of Cancer Signalling NetworkTSEN15
Wikipedia pathwaysTSEN15
Orthology - Evolution
OrthoDB116461
GeneTree (enSembl)ENSG00000198860
Phylogenetic Trees/Animal Genes : TreeFamTSEN15
Homologs : HomoloGeneTSEN15
Homology/Alignments : Family Browser (UCSC)TSEN15
Gene fusions - Rearrangements
Fusion : QuiverTSEN15
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTSEN15 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TSEN15
dbVarTSEN15
ClinVarTSEN15
MonarchTSEN15
1000_GenomesTSEN15 
Exome Variant ServerTSEN15
GNOMAD BrowserENSG00000198860
Varsome BrowserTSEN15
ACMGTSEN15 variants
VarityQ8WW01
Genomic Variants (DGV)TSEN15 [DGVbeta]
DECIPHERTSEN15 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTSEN15 
Mutations
ICGC Data PortalTSEN15 
TCGA Data PortalTSEN15 
Broad Tumor PortalTSEN15
OASIS PortalTSEN15 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTSEN15  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DTSEN15
Mutations and Diseases : HGMDTSEN15
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaTSEN15
DgiDB (Drug Gene Interaction Database)TSEN15
DoCM (Curated mutations)TSEN15
CIViC (Clinical Interpretations of Variants in Cancer)TSEN15
Cancer3DTSEN15
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM608756    617026   
Orphanet2334   
DisGeNETTSEN15
MedgenTSEN15
Genetic Testing Registry TSEN15
NextProtQ8WW01 [Medical]
GENETestsTSEN15
Target ValidationTSEN15
Huge Navigator TSEN15 [HugePedia]
ClinGenTSEN15
Clinical trials, drugs, therapy
MyCancerGenomeTSEN15
Protein Interactions : CTDTSEN15
Pharm GKB GenePA162407135
PharosQ8WW01
Clinical trialTSEN15
Miscellaneous
canSAR (ICR)TSEN15
HarmonizomeTSEN15
DataMed IndexTSEN15
Probes
Litterature
PubMed24 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXTSEN15
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 16:27:06 CEST 2021

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