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TSFM (Ts translation elongation factor, mitochondrial)

Identity

Alias (NCBI)EFTS
EFTSMT
HGNC (Hugo) TSFM
HGNC Alias symbEF-Tsmt
EF-TS
LocusID (NCBI) 10102
Atlas_Id 54728
Location 12q14.1  [Link to chromosome band 12q14]
Location_base_pair Starts at 57782787 and ends at 57797587 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
METTL21B (12q14.1) / TSFM (12q14.1)TSFM (12q14.1) / IFNG (12q15)TSFM (12q14.1) / INHBE (12q13.3)
TSFM (12q14.1) / MARCH9 (12q14.1)TSFM (12q14.1) / NUP107 (12q15)TSFM (12q14.1) / TJAP1 (6p21.1)
TSFM 12q14.1 / MARCH9 12q14.1TSFM 12q14.1 / NUP107 12q15

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)TSFM   12367
Cards
Entrez_Gene (NCBI)TSFM    Ts translation elongation factor, mitochondrial
AliasesEFTS; EFTSMT
GeneCards (Weizmann)TSFM
Ensembl hg19 (Hinxton)ENSG00000123297 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000123297 [Gene_View]  ENSG00000123297 [Sequence]  chr12:57782787-57797587 [Contig_View]  TSFM [Vega]
ICGC DataPortalENSG00000123297
TCGA cBioPortalTSFM
AceView (NCBI)TSFM
Genatlas (Paris)TSFM
SOURCE (Princeton)TSFM
Genetics Home Reference (NIH)TSFM
Genomic and cartography
GoldenPath hg38 (UCSC)TSFM  -     chr12:57782787-57797587 +  12q14.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TSFM  -     12q14.1   [Description]    (hg19-Feb_2009)
GoldenPathTSFM - 12q14.1 [CytoView hg19]  TSFM - 12q14.1 [CytoView hg38]
ImmunoBaseENSG00000123297
Genome Data Viewer NCBITSFM [Mapview hg19]  
OMIM604723   610505   
Gene and transcription
Genbank (Entrez)AF110399 AK295323 AK304621 AK308981 AK313453
RefSeq transcript (Entrez)NM_001172695 NM_001172696 NM_001172697 NM_005726
Consensus coding sequences : CCDS (NCBI)TSFM
Gene ExpressionTSFM [ NCBI-GEO ]   TSFM [ EBI - ARRAY_EXPRESS ]   TSFM [ SEEK ]   TSFM [ MEM ]
Gene Expression Viewer (FireBrowse)TSFM [ Firebrowse - Broad ]
GenevisibleExpression of TSFM in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)10102
GTEX Portal (Tissue expression)TSFM
Human Protein AtlasENSG00000123297-TSFM [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP43897   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP43897  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP43897
PhosPhoSitePlusP43897
Domaine pattern : Prosite (Expaxy)EF_TS_1 (PS01126)    EF_TS_2 (PS01127)   
Domains : Interpro (EBI)EF-Ts_dimer_sf    Transl_elong_EFTs/EF1B    Transl_elong_EFTs/EF1B_dimer    Transl_elong_Ts_CS    UBA-like_sf   
Domain families : Pfam (Sanger)EF_TS (PF00889)   
Domain families : Pfam (NCBI)pfam00889   
Conserved Domain (NCBI)TSFM
PDB (RSDB)2CP9   
PDB Europe2CP9   
PDB (PDBSum)2CP9   
PDB (IMB)2CP9   
Structural Biology KnowledgeBase2CP9   
SCOP (Structural Classification of Proteins)2CP9   
CATH (Classification of proteins structures)2CP9   
SuperfamilyP43897
AlphaFold pdb e-kbP43897   
Human Protein Atlas [tissue]ENSG00000123297-TSFM [tissue]
HPRD05285
Protein Interaction databases
DIP (DOE-UCLA)P43897
IntAct (EBI)P43897
BioGRIDTSFM
STRING (EMBL)TSFM
ZODIACTSFM
Ontologies - Pathways
QuickGOP43897
Ontology : AmiGORNA binding  translation elongation factor activity  protein binding  nucleoplasm  mitochondrion  mitochondrial matrix  translational elongation  regulation of DNA-templated transcription, elongation  mitochondrial translational elongation  regulation of mitochondrial translation  
Ontology : EGO-EBIRNA binding  translation elongation factor activity  protein binding  nucleoplasm  mitochondrion  mitochondrial matrix  translational elongation  regulation of DNA-templated transcription, elongation  mitochondrial translational elongation  regulation of mitochondrial translation  
NDEx NetworkTSFM
Atlas of Cancer Signalling NetworkTSFM
Wikipedia pathwaysTSFM
Orthology - Evolution
OrthoDB10102
GeneTree (enSembl)ENSG00000123297
Phylogenetic Trees/Animal Genes : TreeFamTSFM
Homologs : HomoloGeneTSFM
Homology/Alignments : Family Browser (UCSC)TSFM
Gene fusions - Rearrangements
Fusion : MitelmanTSFM/IFNG [12q14.1/12q15]  
Fusion : MitelmanTSFM/INHBE [12q14.1/12q13.3]  
Fusion : MitelmanTSFM/MARCH9 [12q14.1/12q14.1]  
Fusion : MitelmanTSFM/NUP107 [12q14.1/12q15]  
Fusion : MitelmanTSFM/TJAP1 [12q14.1/6p21.1]  
Fusion : QuiverTSFM
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTSFM [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TSFM
dbVarTSFM
ClinVarTSFM
MonarchTSFM
1000_GenomesTSFM 
Exome Variant ServerTSFM
GNOMAD BrowserENSG00000123297
Varsome BrowserTSFM
ACMGTSFM variants
VarityP43897
Genomic Variants (DGV)TSFM [DGVbeta]
DECIPHERTSFM [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTSFM 
Mutations
ICGC Data PortalTSFM 
TCGA Data PortalTSFM 
Broad Tumor PortalTSFM
OASIS PortalTSFM [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTSFM  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DTSFM
Mutations and Diseases : HGMDTSFM
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaTSFM
DgiDB (Drug Gene Interaction Database)TSFM
DoCM (Curated mutations)TSFM
CIViC (Clinical Interpretations of Variants in Cancer)TSFM
Cancer3DTSFM
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM604723    610505   
Orphanet17773   
DisGeNETTSFM
MedgenTSFM
Genetic Testing Registry TSFM
NextProtP43897 [Medical]
GENETestsTSFM
Target ValidationTSFM
Huge Navigator TSFM [HugePedia]
ClinGenTSFM
Clinical trials, drugs, therapy
MyCancerGenomeTSFM
Protein Interactions : CTDTSFM
Pharm GKB GenePA37037
PharosP43897
Clinical trialTSFM
Miscellaneous
canSAR (ICR)TSFM
HarmonizomeTSFM
DataMed IndexTSFM
Probes
Litterature
PubMed41 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXTSFM
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 15:36:34 CEST 2021

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