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Taking over the Atlas
Dear Colleagues,
The Atlas, once more, is in great danger, and I will have to proceed to a collective economic lay-off of all the team involved in the Atlas before the begining of April 2015 (a foundation having suddenly withdrawn its commitment to support the Atlas). I ask you herein if any Scientific Society (a Society of Cytogenetics, of Clinical Genetics, of Hematology, or a Cancer Society, or any other...), any University and/or Hospital, any Charity, or any database would be interested in taking over the Atlas, in whole or in part. If taking charge of the whole lot is too big, a consortium of various actors could be the solution (I am myself trying to find partners). Could you please spread the information, contact the relevant authorities, and find partners.
Survival of the Atlas will be critically dependant upon your ability to find solutions (and urgently!).
Kind regards.
Jean-Loup Huret
Donations are also welcome

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TSG101 (tumor susceptibility 101)

Identity

Other namesTSG10
VPS23
HGNC (Hugo) TSG101
LocusID (NCBI) 7251
Location 11p15.1
Location_base_pair Starts at 18501858 and ends at 18548503 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)TSG101   15971
Cards
Entrez_Gene (NCBI)TSG101  7251  tumor susceptibility 101
GeneCards (Weizmann)TSG101
Ensembl hg19 (Hinxton)ENSG00000074319 [Gene_View]  chr11:18501858-18548503 [Contig_View]  TSG101 [Vega]
Ensembl hg38 (Hinxton)ENSG00000074319 [Gene_View]  chr11:18501858-18548503 [Contig_View]  TSG101 [Vega]
ICGC DataPortalENSG00000074319
cBioPortalTSG101
AceView (NCBI)TSG101
Genatlas (Paris)TSG101
WikiGenes7251
SOURCE (Princeton)TSG101
Genomic and cartography
GoldenPath hg19 (UCSC)TSG101  -     chr11:18501858-18548503 -  11p15.1   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)TSG101  -     11p15.1   [Description]    (hg38-Dec_2013)
EnsemblTSG101 - 11p15.1 [CytoView hg19]  TSG101 - 11p15.1 [CytoView hg38]
Mapping of homologs : NCBITSG101 [Mapview hg19]  TSG101 [Mapview hg38]
OMIM114480   601387   
Gene and transcription
Genbank (Entrez)AK130787 AU138453 AY207473 AY207474 BC002487
RefSeq transcript (Entrez)NM_006292
RefSeq genomic (Entrez)AC_000143 NC_000011 NC_018922 NG_012138 NT_009237 NW_001838022 NW_004929378
Consensus coding sequences : CCDS (NCBI)TSG101
Cluster EST : UnigeneHs.523512 [ NCBI ]
CGAP (NCI)Hs.523512
Alternative Splicing : Fast-db (Paris)GSHG0005633
Alternative Splicing GalleryENSG00000074319
Gene ExpressionTSG101 [ NCBI-GEO ]     TSG101 [ SEEK ]   TSG101 [ MEM ]
SOURCE (Princeton)Expression in : [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ99816 (Uniprot)
NextProtQ99816  [Medical]
With graphics : InterProQ99816
Splice isoforms : SwissVarQ99816 (Swissvar)
Domaine pattern : Prosite (Expaxy)SB (PS51312)    UEV (PS51322)   
Domains : Interpro (EBI)Steadiness_box    UBQ-conjugating_enzyme/RWD    UEV_N   
Related proteins : CluSTrQ99816
Domain families : Pfam (Sanger)UEV (PF05743)    Vps23_core (PF09454)   
Domain families : Pfam (NCBI)pfam05743    pfam09454   
DMDM Disease mutations7251
Blocks (Seattle)Q99816
PDB (SRS)1KPP    1KPQ    1M4P    1M4Q    1S1Q    2F0R    3IV1    3OBQ    3OBS    3OBU    3OBX    3P9G    3P9H    4EJE   
PDB (PDBSum)1KPP    1KPQ    1M4P    1M4Q    1S1Q    2F0R    3IV1    3OBQ    3OBS    3OBU    3OBX    3P9G    3P9H    4EJE   
PDB (IMB)1KPP    1KPQ    1M4P    1M4Q    1S1Q    2F0R    3IV1    3OBQ    3OBS    3OBU    3OBX    3P9G    3P9H    4EJE   
PDB (RSDB)1KPP    1KPQ    1M4P    1M4Q    1S1Q    2F0R    3IV1    3OBQ    3OBS    3OBU    3OBX    3P9G    3P9H    4EJE   
Human Protein AtlasENSG00000074319
Peptide AtlasQ99816
HPRD03229
IPIIPI00018434   IPI00219826   IPI00383946   IPI01014105   
Protein Interaction databases
DIP (DOE-UCLA)Q99816
IntAct (EBI)Q99816
FunCoupENSG00000074319
BioGRIDTSG101
IntegromeDBTSG101
STRING (EMBL)TSG101
Ontologies - Pathways
QuickGOQ99816
Ontology : AmiGOESCRT I complex  regulation of cell growth  DNA binding  transcription corepressor activity  protein binding  nucleolus  cytoplasm  cytoplasm  early endosome  late endosome  multivesicular body  plasma membrane  cellular protein modification process  cell cycle arrest  negative regulation of cell proliferation  endosome membrane  protein transport  viral process  endosomal transport  viral life cycle  virion assembly  viral protein processing  keratinocyte differentiation  ubiquitin protein ligase binding  late endosome membrane  protein homodimerization activity  ubiquitin binding  ubiquitin binding  ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway  ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway  ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway  negative regulation of transcription, DNA-templated  viral budding  viral budding  calcium-dependent protein binding  cell division  membrane organization  extracellular vesicular exosome  intracellular transport of virus  
Ontology : EGO-EBIESCRT I complex  regulation of cell growth  DNA binding  transcription corepressor activity  protein binding  nucleolus  cytoplasm  cytoplasm  early endosome  late endosome  multivesicular body  plasma membrane  cellular protein modification process  cell cycle arrest  negative regulation of cell proliferation  endosome membrane  protein transport  viral process  endosomal transport  viral life cycle  virion assembly  viral protein processing  keratinocyte differentiation  ubiquitin protein ligase binding  late endosome membrane  protein homodimerization activity  ubiquitin binding  ubiquitin binding  ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway  ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway  ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway  negative regulation of transcription, DNA-templated  viral budding  viral budding  calcium-dependent protein binding  cell division  membrane organization  extracellular vesicular exosome  intracellular transport of virus  
Pathways : BIOCARTAStathmin and breast cancer resistance to antimicrotubule agents [Genes]   
Pathways : KEGGEndocytosis   
Protein Interaction DatabaseTSG101
DoCM (Curated mutations)TSG101
Wikipedia pathwaysTSG101
Gene fusion - rearrangements
Polymorphisms : SNP, variants
NCBI Variation ViewerTSG101 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TSG101
dbVarTSG101
ClinVarTSG101
1000_GenomesTSG101 
Exome Variant ServerTSG101
SNP (GeneSNP Utah)TSG101
SNP : HGBaseTSG101
Genetic variants : HAPMAPTSG101
Genomic Variants (DGV)TSG101 [DGVbeta]
Mutations
ICGC Data PortalENSG00000074319 
Somatic Mutations in Cancer : COSMICTSG101 
CONAN: Copy Number AnalysisTSG101 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] 
Diseases
DECIPHER (Syndromes)11:18501858-18548503
Mutations and Diseases : HGMDTSG101
OMIM114480    601387   
MedgenTSG101
NextProtQ99816 [Medical]
GENETestsTSG101
Disease Genetic AssociationTSG101
Huge Navigator TSG101 [HugePedia]  TSG101 [HugeCancerGEM]
snp3D : Map Gene to Disease7251
DGIdb (Drug Gene Interaction db)TSG101
General knowledge
Homologs : HomoloGeneTSG101
Homology/Alignments : Family Browser (UCSC)TSG101
Phylogenetic Trees/Animal Genes : TreeFamTSG101
Chemical/Protein Interactions : CTD7251
Chemical/Pharm GKB GenePA38068
Clinical trialTSG101
Cancer Resource (Charite)ENSG00000074319
Other databases
Probes
Litterature
PubMed219 Pubmed reference(s) in Entrez
CoreMineTSG101
GoPubMedTSG101
iHOPTSG101
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated12-2014Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Sat Feb 14 19:11:51 CET 2015

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jlhuret@AtlasGeneticsOncology.org.