Atlas of Genetics and Cytogenetics in Oncology and Haematology

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TSG101 (tumor susceptibility gene 101)

Identity

Other namesTSG10
VPS23
HGNC (Hugo) TSG101
LocusID (NCBI) 7251
Location 11p15.1
Location_base_pair Starts at 18501858 and ends at 18548503 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)TSG101   15971
Entrez_Gene (NCBI)TSG101  7251  tumor susceptibility gene 101
Cards
GeneCards (Weizmann)TSG101
Ensembl (Hinxton)ENSG00000074319 [Gene_View]  chr11:18501858-18548503 [Contig_View]  TSG101 [Vega]
AceView (NCBI)TSG101
Genatlas (Paris)TSG101
SOURCE (Stanford)NM_006292
Genomic and cartography
GoldenPath (UCSC)TSG101  -  11p15.1   chr11:18501858-18548503 -  11p15.1   [Description]    (hg19-Feb_2009)
EnsemblTSG101 - 11p15.1 [CytoView]
Mapping of homologs : NCBITSG101 [Mapview]
OMIM114480   601387   
Gene and transcription
Genbank (Entrez)AK130787 AU138453 AY207473 AY207474 BC002487
RefSeq transcript (SRS)NM_006292
RefSeq transcript (Entrez)NM_006292
RefSeq genomic (SRS)AC_000143 NC_000011 NC_018922 NG_012138 NT_009237 NW_001838022 NW_004078070
RefSeq genomic (Entrez)AC_000143 NC_000011 NC_018922 NG_012138 NT_009237 NW_001838022 NW_004078070
Consensus coding sequences : CCDS (NCBI)TSG101
Cluster EST : UnigeneHs.523512 [ SRS ] Hs.523512 [ NCBI ]
CGAP (NCI)Hs.523512
Alternative Splicing : Fast-db (Paris)GSHG0005633
Alternative Splicing GalleryENSG00000074319
Gene ExpressionTSG101 [ NCBI-GEO ]   TSG101 [ EBI - ARRAY_EXPRESS ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ99816 (SRS) Q99816 (Uniprot)
NextProtQ99816
With graphics : InterProQ99816
Splice isoforms : SwissVarQ99816(Swissvar)
Domaine pattern : Prosite (SRS)SB (PS51312)    UBIQUITIN_CONJUGAT_1 (PS00183)    UBIQUITIN_CONJUGAT_2 (PS50127)    UEV (PS51322)   
Domaine pattern : Prosite (Expaxy)SB (PS51312)    UBIQUITIN_CONJUGAT_1 (PS00183)    UBIQUITIN_CONJUGAT_2 (PS50127)    UEV (PS51322)   
Domains : Interpro (SRS)Steadiness_box    UBQ-conjugating_enzyme/RWD    UEV_N   
Domains : Interpro (EBI)Steadiness_box    UBQ-conjugating_enzyme/RWD    UEV_N   
Related proteins : CluSTrQ99816
Domain families : Pfam (SRS)UEV (PF05743)    Vps23_core (PF09454)   
Domain families : Pfam (Sanger)UEV (PF05743)    Vps23_core (PF09454)   
Domain families : Pfam (NCBI)pfam05743    pfam09454   
DMDM7251
Blocks (Seattle)Q99816
PDB (SRS)1KPP    1KPQ    1M4P    1M4Q    1S1Q    2F0R    3IV1    3OBQ    3OBS    3OBU    3OBX    3P9G    3P9H   
PDB (PDBSum)1KPP    1KPQ    1M4P    1M4Q    1S1Q    2F0R    3IV1    3OBQ    3OBS    3OBU    3OBX    3P9G    3P9H   
PDB (IMB)1KPP    1KPQ    1M4P    1M4Q    1S1Q    2F0R    3IV1    3OBQ    3OBS    3OBU    3OBX    3P9G    3P9H   
PDB (RSDB)1KPP    1KPQ    1M4P    1M4Q    1S1Q    2F0R    3IV1    3OBQ    3OBS    3OBU    3OBX    3P9G    3P9H   
Human Protein AtlasENSG00000074319
HPRD03229
IPIIPI00018434   IPI00219826   IPI00383946   IPI01014105   
Protein Interaction databases
DIP (DOE-UCLA)Q99816
IntAct (EBI)Q99816
FunCoupENSG00000074319
REACTOMETSG101
Protein Interaction Database7251
BioGRIDTSG101
InParanoidQ99816
Interologous Interaction database Q99816
IntegromeDBTSG101
Polymorphism : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)TSG101
SNP (GeneSNP Utah)TSG101
SNP : HGBaseTSG101
Genetic variants : HAPMAPTSG101
Somatic Mutations in Cancer : COSMICTSG101 
CONAN: Copy Number AnalysisTSG101 
Mutations and Diseases : HGMDTSG101
OMIM114480    601387   
GENETests114480    601387   
Disease Genetic AssociationTSG101
Huge Navigator TSG101 [HugePedia]  TSG101 [HugeCancerGEM]
Genomic VariantsTSG101  TSG101 [DGVbeta]
snp3D : Map Gene to Disease7251
General knowledge
Homologs : HomoloGeneTSG101
Homology/Alignments : Family Browser (UCSC)TSG101
Phylogenetic Trees/Animal Genes : TreeFamTSG101
Chemical/Protein Interactions : CTD7251
Chemical/Pharm GKB GenePA38068
Clinical trialTSG101
Cancer Resource (Charite)ENSG00000074319
Ontology : AmiGOregulation of cell growth  DNA binding  transcription corepressor activity  protein binding  nucleolus  cytoplasm  cytoplasm  early endosome  late endosome  multivesicular body  plasma membrane  protein monoubiquitination  cell cycle arrest  negative regulation of cell proliferation  endosome to lysosome transport  endosome membrane  protein transport  viral reproduction  cellular membrane organization  endosomal transport  keratinocyte differentiation  ligand-dependent nuclear receptor transcription coactivator activity  ubiquitin protein ligase binding  late endosome membrane  ubiquitin binding  ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway  negative regulation of transcription, DNA-dependent  non-lytic virus budding  non-lytic virus budding  egress of virus within host cell  calcium-dependent protein binding  cell division  
Ontology : EGO-EBIregulation of cell growth  DNA binding  transcription corepressor activity  protein binding  nucleolus  cytoplasm  cytoplasm  early endosome  late endosome  multivesicular body  plasma membrane  protein monoubiquitination  cell cycle arrest  negative regulation of cell proliferation  endosome to lysosome transport  endosome membrane  protein transport  viral reproduction  cellular membrane organization  endosomal transport  keratinocyte differentiation  ligand-dependent nuclear receptor transcription coactivator activity  ubiquitin protein ligase binding  late endosome membrane  ubiquitin binding  ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway  negative regulation of transcription, DNA-dependent  non-lytic virus budding  non-lytic virus budding  egress of virus within host cell  calcium-dependent protein binding  cell division  
Pathways : BIOCARTAStathmin and breast cancer resistance to antimicrotubule agents [Genes]   
Other databases
Probes
Litterature
PubMed196 Pubmed reference(s) in Entrez
PubGeneTSG101
iHOPTSG101
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated01-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed May 1 12:37:51 CEST 2013
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