Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

TSHB (thyroid stimulating hormone, beta)

Identity

Other namesTSH-B
TSH-BETA
HGNC (Hugo) TSHB
LocusID (NCBI) 7252
Location 1p13.2
Location_base_pair Starts at 115572445 and ends at 115576930 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

External links

Nomenclature
HGNC (Hugo)TSHB   12372
Cards
Entrez_Gene (NCBI)TSHB  7252  thyroid stimulating hormone, beta
GeneCards (Weizmann)TSHB
Ensembl hg19 (Hinxton)ENSG00000134200 [Gene_View]  chr1:115572445-115576930 [Contig_View]  TSHB [Vega]
Ensembl hg38 (Hinxton)ENSG00000134200 [Gene_View]  chr1:115572445-115576930 [Contig_View]  TSHB [Vega]
ICGC DataPortalENSG00000134200
cBioPortalTSHB
AceView (NCBI)TSHB
Genatlas (Paris)TSHB
WikiGenes7252
SOURCE (Princeton)TSHB
Genomic and cartography
GoldenPath hg19 (UCSC)TSHB  -     chr1:115572445-115576930 +  1p13.2   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)TSHB  -     1p13.2   [Description]    (hg38-Dec_2013)
EnsemblTSHB - 1p13.2 [CytoView hg19]  TSHB - 1p13.2 [CytoView hg38]
Mapping of homologs : NCBITSHB [Mapview hg19]  TSHB [Mapview hg38]
OMIM188540   275100   
Gene and transcription
Genbank (Entrez)BC069298 HQ448420 S51112
RefSeq transcript (Entrez)NM_000549 NM_001277991
RefSeq genomic (Entrez)AC_000133 NC_000001 NC_018912 NG_015891 NT_032977 NW_001838594 NW_004929290
Consensus coding sequences : CCDS (NCBI)TSHB
Cluster EST : UnigeneHs.406687 [ NCBI ]
CGAP (NCI)Hs.406687
Alternative Splicing : Fast-db (Paris)GSHG0000836
Alternative Splicing GalleryENSG00000134200
Gene ExpressionTSHB [ NCBI-GEO ]     TSHB [ SEEK ]   TSHB [ MEM ]
SOURCE (Princeton)Expression in : [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP01222 (Uniprot)
NextProtP01222  [Medical]
With graphics : InterProP01222
Splice isoforms : SwissVarP01222 (Swissvar)
Domaine pattern : Prosite (Expaxy)GLYCO_HORMONE_BETA_1 (PS00261)    GLYCO_HORMONE_BETA_2 (PS00689)   
Domains : Interpro (EBI)Cystine-knot_cytokine    Glyco_hormone_CN    Gonadotropin_bsu    Gonadotropin_bsu_CS   
Related proteins : CluSTrP01222
Domain families : Pfam (Sanger)Cys_knot (PF00007)   
Domain families : Pfam (NCBI)pfam00007   
Domain families : Smart (EMBL)GHB (SM00068)  
DMDM Disease mutations7252
Blocks (Seattle)P01222
Human Protein AtlasENSG00000134200
Peptide AtlasP01222
HPRD11766
IPIIPI00000851   IPI00745707   
Protein Interaction databases
DIP (DOE-UCLA)P01222
IntAct (EBI)P01222
FunCoupENSG00000134200
BioGRIDTSHB
IntegromeDBTSHB
STRING (EMBL)TSHB
Ontologies - Pathways
QuickGOP01222
Ontology : AmiGOhormone activity  extracellular region  G-protein coupled receptor signaling pathway  cell-cell signaling  anatomical structure morphogenesis  peptide hormone processing  response to vitamin A  response to estrogen  cellular protein metabolic process  response to calcium ion  
Ontology : EGO-EBIhormone activity  extracellular region  G-protein coupled receptor signaling pathway  cell-cell signaling  anatomical structure morphogenesis  peptide hormone processing  response to vitamin A  response to estrogen  cellular protein metabolic process  response to calcium ion  
Pathways : KEGGNeuroactive ligand-receptor interaction    Thyroid hormone synthesis    Autoimmune thyroid disease   
Protein Interaction DatabaseTSHB
DoCM (Curated mutations)TSHB
Wikipedia pathwaysTSHB
Gene fusion - rearrangements
Polymorphisms : SNP, variants
NCBI Variation ViewerTSHB [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TSHB
dbVarTSHB
ClinVarTSHB
1000_GenomesTSHB 
Exome Variant ServerTSHB
SNP (GeneSNP Utah)TSHB
SNP : HGBaseTSHB
Genetic variants : HAPMAPTSHB
Genomic VariantsTSHB  TSHB [DGVbeta]
Mutations
ICGC Data PortalENSG00000134200 
Somatic Mutations in Cancer : COSMICTSHB 
CONAN: Copy Number AnalysisTSHB 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] 
Diseases
DECIPHER (Syndromes)1:115572445-115576930
Mutations and Diseases : HGMDTSHB
OMIM188540    275100   
MedgenTSHB
NextProtP01222 [Medical]
GENETestsTSHB
Disease Genetic AssociationTSHB
Huge Navigator TSHB [HugePedia]  TSHB [HugeCancerGEM]
snp3D : Map Gene to Disease7252
DGIdb (Drug Gene Interaction db)TSHB
General knowledge
Homologs : HomoloGeneTSHB
Homology/Alignments : Family Browser (UCSC)TSHB
Phylogenetic Trees/Animal Genes : TreeFamTSHB
Chemical/Protein Interactions : CTD7252
Chemical/Pharm GKB GenePA37041
Clinical trialTSHB
Cancer Resource (Charite)ENSG00000134200
Other databases
Probes
Litterature
PubMed70 Pubmed reference(s) in Entrez
CoreMineTSHB
GoPubMedTSHB
iHOPTSHB
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated12-2014Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Sun Dec 21 02:06:28 CET 2014

Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.