Identity
HGNC
LOCATION
20q13.2
LOCUSID
ALIAS
C20orf17,OVC10-2,TSH2,ZABC2,ZNF218
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 128553
MIM: 614118
HGNC: 13010
Ensembl: ENSG00000182463
Variants:
dbSNP: 128553
ClinVar: 128553
TCGA: ENSG00000182463
COSMIC: TSHZ2
RNA/Proteins
Expression (GTEx)
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA166120929 | severe cutaneous adverse reactions | Disease | VariantAnnotation | associated | PD | 29193002 | |
| PA448320 | allopurinol | Chemical | VariantAnnotation | associated | PD | 29193002 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 33850468 | 2021 | Overexpression of Teashirt Homolog 2 suppresses cell proliferation and predicts the favorable survival of Lung Adenocarcinoma. | 2 |
| 34158398 | 2021 | TSHZ2 is an EGF-regulated tumor suppressor that binds to the cytokinesis regulator PRC1 and inhibits metastasis. | 5 |
| 33850468 | 2021 | Overexpression of Teashirt Homolog 2 suppresses cell proliferation and predicts the favorable survival of Lung Adenocarcinoma. | 2 |
| 34158398 | 2021 | TSHZ2 is an EGF-regulated tumor suppressor that binds to the cytokinesis regulator PRC1 and inhibits metastasis. | 5 |
| 26744317 | 2016 | Down-regulation of the zinc-finger homeobox protein TSHZ2 releases GLI1 from the nuclear repressor complex to restore its transcriptional activity during mammary tumorigenesis. | 18 |
| 26744317 | 2016 | Down-regulation of the zinc-finger homeobox protein TSHZ2 releases GLI1 from the nuclear repressor complex to restore its transcriptional activity during mammary tumorigenesis. | 18 |
| 21423795 | 2011 | Rare and frequent promoter methylation, respectively, of TSHZ2 and 3 genes that are both downregulated in expression in breast and prostate cancers. | 25 |
| 21423795 | 2011 | Rare and frequent promoter methylation, respectively, of TSHZ2 and 3 genes that are both downregulated in expression in breast and prostate cancers. | 25 |
| 19745106 | 2010 | Analysis of TSHZ2 and TSHZ3 genes in congenital pelvi-ureteric junction obstruction. | 13 |
| 19745106 | 2010 | Analysis of TSHZ2 and TSHZ3 genes in congenital pelvi-ureteric junction obstruction. | 13 |
| 20379614 | 2010 | Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. | 78 |
| 20628086 | 2010 | Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. | 15 |
| 19745106 | 2010 | Analysis of TSHZ2 and TSHZ3 genes in congenital pelvi-ureteric junction obstruction. | 13 |
| 19745106 | 2010 | Analysis of TSHZ2 and TSHZ3 genes in congenital pelvi-ureteric junction obstruction. | 13 |
| 20379614 | 2010 | Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. | 78 |
Citation
Dessen P
TSHZ2 (teashirt zinc finger homeobox 2)
Atlas Genet Cytogenet Oncol Haematol. 2011-07-01
Online version: http://atlasgeneticsoncology.org/gene/52293/tshz2
