Atlas of Genetics and Cytogenetics in Oncology and Haematology


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TSHZ3 (teashirt zinc finger homeobox 3)

Identity

Alias_namesZNF537
zinc finger protein 537
teashirt family zinc finger 3
Alias_symbol (synonym)KIAA1474
TSH3
Other alias
HGNC (Hugo) TSHZ3
LocusID (NCBI) 57616
Atlas_Id 52299
Location 19q12  [Link to chromosome band 19q12]
Location_base_pair Starts at 31274945 and ends at 31349525 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
SH3PXD2A (10q24.33) / TSHZ3 (19q12)TSHZ3 (19q12) / CEACAM7 (19q13.2)TSHZ3 (19q12) / IFNL1 (19q13.2)
TSHZ3 19q12 / CEACAM7 19q13.2TSHZ3 19q12 IL29

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)TSHZ3   30700
Cards
Entrez_Gene (NCBI)TSHZ3  57616  teashirt zinc finger homeobox 3
AliasesTSH3; ZNF537
GeneCards (Weizmann)TSHZ3
Ensembl hg19 (Hinxton)ENSG00000121297 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000121297 [Gene_View]  chr19:31274945-31349525 [Contig_View]  TSHZ3 [Vega]
ICGC DataPortalENSG00000121297
TCGA cBioPortalTSHZ3
AceView (NCBI)TSHZ3
Genatlas (Paris)TSHZ3
WikiGenes57616
SOURCE (Princeton)TSHZ3
Genetics Home Reference (NIH)TSHZ3
Genomic and cartography
GoldenPath hg38 (UCSC)TSHZ3  -     chr19:31274945-31349525 -  19q12   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TSHZ3  -     19q12   [Description]    (hg19-Feb_2009)
EnsemblTSHZ3 - 19q12 [CytoView hg19]  TSHZ3 - 19q12 [CytoView hg38]
Mapping of homologs : NCBITSHZ3 [Mapview hg19]  TSHZ3 [Mapview hg38]
OMIM614119   
Gene and transcription
Genbank (Entrez)AB040907 AI015687 AI380291 AK291466 AK293267
RefSeq transcript (Entrez)NM_020856
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)TSHZ3
Cluster EST : UnigeneHs.278436 [ NCBI ]
CGAP (NCI)Hs.278436
Alternative Splicing GalleryENSG00000121297
Gene ExpressionTSHZ3 [ NCBI-GEO ]   TSHZ3 [ EBI - ARRAY_EXPRESS ]   TSHZ3 [ SEEK ]   TSHZ3 [ MEM ]
Gene Expression Viewer (FireBrowse)TSHZ3 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)57616
GTEX Portal (Tissue expression)TSHZ3
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ63HK5   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ63HK5  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ63HK5
Splice isoforms : SwissVarQ63HK5
PhosPhoSitePlusQ63HK5
Domaine pattern : Prosite (Expaxy)HOMEOBOX_2 (PS50071)    ZINC_FINGER_C2H2_1 (PS00028)    ZINC_FINGER_C2H2_2 (PS50157)   
Domains : Interpro (EBI)Homeobox-like    Homeobox_dom    Teashirt_fam    Tshz3    Znf_C2H2    Znf_C2H2-like   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Domain families : Smart (EMBL)HOX (SM00389)  ZnF_C2H2 (SM00355)  
Conserved Domain (NCBI)TSHZ3
DMDM Disease mutations57616
Blocks (Seattle)TSHZ3
PDB (SRS)2DMI   
PDB (PDBSum)2DMI   
PDB (IMB)2DMI   
PDB (RSDB)2DMI   
Structural Biology KnowledgeBase2DMI   
SCOP (Structural Classification of Proteins)2DMI   
CATH (Classification of proteins structures)2DMI   
SuperfamilyQ63HK5
Human Protein AtlasENSG00000121297
Peptide AtlasQ63HK5
HPRD18351
IPIIPI00001743   
Protein Interaction databases
DIP (DOE-UCLA)Q63HK5
IntAct (EBI)Q63HK5
FunCoupENSG00000121297
BioGRIDTSHZ3
STRING (EMBL)TSHZ3
ZODIACTSHZ3
Ontologies - Pathways
QuickGOQ63HK5
Ontology : AmiGOnegative regulation of transcription from RNA polymerase II promoter  transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding  regulation of respiratory gaseous exchange by neurological system process  DNA binding  chromatin binding  protein binding  nucleus  nucleoplasm  transcription, DNA-templated  regulation of transcription from RNA polymerase II promoter  multicellular organism development  growth cone  negative regulation of transcription, DNA-templated  metal ion binding  positive regulation of synaptic transmission, glutamatergic  long-term synaptic potentiation  
Ontology : EGO-EBInegative regulation of transcription from RNA polymerase II promoter  transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding  regulation of respiratory gaseous exchange by neurological system process  DNA binding  chromatin binding  protein binding  nucleus  nucleoplasm  transcription, DNA-templated  regulation of transcription from RNA polymerase II promoter  multicellular organism development  growth cone  negative regulation of transcription, DNA-templated  metal ion binding  positive regulation of synaptic transmission, glutamatergic  long-term synaptic potentiation  
NDEx NetworkTSHZ3
Atlas of Cancer Signalling NetworkTSHZ3
Wikipedia pathwaysTSHZ3
Orthology - Evolution
OrthoDB57616
GeneTree (enSembl)ENSG00000121297
Phylogenetic Trees/Animal Genes : TreeFamTSHZ3
HOVERGENQ63HK5
HOGENOMQ63HK5
Homologs : HomoloGeneTSHZ3
Homology/Alignments : Family Browser (UCSC)TSHZ3
Gene fusions - Rearrangements
Fusion : MitelmanTSHZ3/CEACAM7 [19q12/19q13.2]  
Fusion : MitelmanTSHZ3/IFNL1 [19q12/19q13.2]  [t(19;19)(q12;q13)]  
Fusion: TCGATSHZ3 19q12 CEACAM7 19q13.2 LGG
Fusion: TCGATSHZ3 19q12 IL29 HNSC
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTSHZ3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TSHZ3
dbVarTSHZ3
ClinVarTSHZ3
1000_GenomesTSHZ3 
Exome Variant ServerTSHZ3
ExAC (Exome Aggregation Consortium)TSHZ3 (select the gene name)
Genetic variants : HAPMAP57616
Genomic Variants (DGV)TSHZ3 [DGVbeta]
DECIPHERTSHZ3 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTSHZ3 
Mutations
ICGC Data PortalTSHZ3 
TCGA Data PortalTSHZ3 
Broad Tumor PortalTSHZ3
OASIS PortalTSHZ3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTSHZ3  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDTSHZ3
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)MSeqDR-LSDB Mitochondrial Disease Locus Specific Database
BioMutasearch TSHZ3
DgiDB (Drug Gene Interaction Database)TSHZ3
DoCM (Curated mutations)TSHZ3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)TSHZ3 (select a term)
intoGenTSHZ3
Cancer3DTSHZ3(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM614119   
Orphanet
MedgenTSHZ3
Genetic Testing Registry TSHZ3
NextProtQ63HK5 [Medical]
TSGene57616
GENETestsTSHZ3
Target ValidationTSHZ3
Huge Navigator TSHZ3 [HugePedia]
snp3D : Map Gene to Disease57616
BioCentury BCIQTSHZ3
ClinGenTSHZ3
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD57616
Chemical/Pharm GKB GenePA134887020
Clinical trialTSHZ3
Miscellaneous
canSAR (ICR)TSHZ3 (select the gene name)
Probes
Litterature
PubMed25 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTSHZ3
EVEXTSHZ3
GoPubMedTSHZ3
iHOPTSHZ3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed Jun 7 13:01:06 CEST 2017

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