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TSLP (thymic stromal lymphopoietin)

Identity

Other alias-
HGNC (Hugo) TSLP
LocusID (NCBI) 85480
Atlas_Id 51456
Location 5q22.1  [Link to chromosome band 5q22]
Location_base_pair Starts at 111071692 and ends at 111078024 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Leukemias implicated (Data extracted from papers in the Atlas) [ 1 ]
  Acute lymphoblastic leukemia in Down syndrome


External links

Nomenclature
HGNC (Hugo)TSLP   30743
Cards
Entrez_Gene (NCBI)TSLP  85480  thymic stromal lymphopoietin
Aliases
GeneCards (Weizmann)TSLP
Ensembl hg19 (Hinxton)ENSG00000145777 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000145777 [Gene_View]  chr5:111071692-111078024 [Contig_View]  TSLP [Vega]
ICGC DataPortalENSG00000145777
TCGA cBioPortalTSLP
AceView (NCBI)TSLP
Genatlas (Paris)TSLP
WikiGenes85480
SOURCE (Princeton)TSLP
Genetics Home Reference (NIH)TSLP
Genomic and cartography
GoldenPath hg38 (UCSC)TSLP  -     chr5:111071692-111078024 +  5q22.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TSLP  -     5q22.1   [Description]    (hg19-Feb_2009)
EnsemblTSLP - 5q22.1 [CytoView hg19]  TSLP - 5q22.1 [CytoView hg38]
Mapping of homologs : NCBITSLP [Mapview hg19]  TSLP [Mapview hg38]
OMIM607003   
Gene and transcription
Genbank (Entrez)AF338732 AL833421 AY037115 BC016720 BC022894
RefSeq transcript (Entrez)NM_033035 NM_138551
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)TSLP
Cluster EST : UnigeneHs.389874 [ NCBI ]
CGAP (NCI)Hs.389874
Alternative Splicing GalleryENSG00000145777
Gene ExpressionTSLP [ NCBI-GEO ]   TSLP [ EBI - ARRAY_EXPRESS ]   TSLP [ SEEK ]   TSLP [ MEM ]
Gene Expression Viewer (FireBrowse)TSLP [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)85480
GTEX Portal (Tissue expression)TSLP
Human Protein AtlasENSG00000145777-TSLP [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ969D9   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ969D9  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ969D9
Splice isoforms : SwissVarQ969D9
PhosPhoSitePlusQ969D9
Domains : Interpro (EBI)TSLP   
Domain families : Pfam (Sanger)TSLP (PF15216)   
Domain families : Pfam (NCBI)pfam15216   
Conserved Domain (NCBI)TSLP
DMDM Disease mutations85480
Blocks (Seattle)TSLP
SuperfamilyQ969D9
Human Protein Atlas [tissue]ENSG00000145777-TSLP [tissue]
Peptide AtlasQ969D9
HPRD06108
IPIIPI00413782   IPI00217207   IPI00977467   
Protein Interaction databases
DIP (DOE-UCLA)Q969D9
IntAct (EBI)Q969D9
FunCoupENSG00000145777
BioGRIDTSLP
STRING (EMBL)TSLP
ZODIACTSLP
Ontologies - Pathways
QuickGOQ969D9
Ontology : AmiGOcytokine activity  extracellular space  
Ontology : EGO-EBIcytokine activity  extracellular space  
Pathways : KEGGCytokine-cytokine receptor interaction    Jak-STAT signaling pathway   
NDEx NetworkTSLP
Atlas of Cancer Signalling NetworkTSLP
Wikipedia pathwaysTSLP
Orthology - Evolution
OrthoDB85480
GeneTree (enSembl)ENSG00000145777
Phylogenetic Trees/Animal Genes : TreeFamTSLP
HOVERGENQ969D9
HOGENOMQ969D9
Homologs : HomoloGeneTSLP
Homology/Alignments : Family Browser (UCSC)TSLP
Gene fusions - Rearrangements
Tumor Fusion PortalTSLP
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTSLP [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TSLP
dbVarTSLP
ClinVarTSLP
1000_GenomesTSLP 
Exome Variant ServerTSLP
ExAC (Exome Aggregation Consortium)ENSG00000145777
GNOMAD BrowserENSG00000145777
Genetic variants : HAPMAP85480
Genomic Variants (DGV)TSLP [DGVbeta]
DECIPHERTSLP [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTSLP 
Mutations
ICGC Data PortalTSLP 
TCGA Data PortalTSLP 
Broad Tumor PortalTSLP
OASIS PortalTSLP [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTSLP  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDTSLP
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch TSLP
DgiDB (Drug Gene Interaction Database)TSLP
DoCM (Curated mutations)TSLP (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)TSLP (select a term)
intoGenTSLP
Cancer3DTSLP(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM607003   
Orphanet
DisGeNETTSLP
MedgenTSLP
Genetic Testing Registry TSLP
NextProtQ969D9 [Medical]
TSGene85480
GENETestsTSLP
Target ValidationTSLP
Huge Navigator TSLP [HugePedia]
snp3D : Map Gene to Disease85480
BioCentury BCIQTSLP
ClinGenTSLP
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD85480
Chemical/Pharm GKB GenePA162407159
Clinical trialTSLP
Miscellaneous
canSAR (ICR)TSLP (select the gene name)
Probes
Litterature
PubMed215 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTSLP
EVEXTSLP
GoPubMedTSLP
iHOPTSLP
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 21 14:39:59 CET 2017

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