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TSN (translin)

Identity

Alias_symbol (synonym)TRSLN
BCLF-1
REHF-1
Other aliasC3PO
RCHF1
TBRBP
HGNC (Hugo) TSN
LocusID (NCBI) 7247
Atlas_Id 42715
Location 2q14.3  [Link to chromosome band 2q14]
Location_base_pair Starts at 121755545 and ends at 121767852 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
ARL4D (17q21.31) / TSN (2q14.3)JMJD1C (10q21.3) / TSN (2q14.3)LOC100505718 () / TSN (2q14.3)
RNF214 (11q23.3) / TSN (2q14.3)SPAG9 (17q21.33) / TSN (2q14.3)TMPRSS11B (4q13.2) / TSN (2q14.3)
TSN (2q14.3) / ARL4D (17q21.31)TSN (2q14.3) / TSN (2q14.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)TSN   12379
Cards
Entrez_Gene (NCBI)TSN  7247  translin
AliasesBCLF-1; C3PO; RCHF1; REHF-1; 
TBRBP; TRSLN
GeneCards (Weizmann)TSN
Ensembl hg19 (Hinxton)ENSG00000211460 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000211460 [Gene_View]  chr2:121755545-121767852 [Contig_View]  TSN [Vega]
ICGC DataPortalENSG00000211460
TCGA cBioPortalTSN
AceView (NCBI)TSN
Genatlas (Paris)TSN
WikiGenes7247
SOURCE (Princeton)TSN
Genetics Home Reference (NIH)TSN
Genomic and cartography
GoldenPath hg38 (UCSC)TSN  -     chr2:121755545-121767852 +  2q14.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TSN  -     2q14.3   [Description]    (hg19-Feb_2009)
EnsemblTSN - 2q14.3 [CytoView hg19]  TSN - 2q14.3 [CytoView hg38]
Mapping of homologs : NCBITSN [Mapview hg19]  TSN [Mapview hg38]
OMIM600575   
Gene and transcription
Genbank (Entrez)AK091915 AK222868 AK296469 AK298812 AK307344
RefSeq transcript (Entrez)NM_001261401 NM_004622
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)TSN
Cluster EST : UnigeneHs.75066 [ NCBI ]
CGAP (NCI)Hs.75066
Alternative Splicing GalleryENSG00000211460
Gene ExpressionTSN [ NCBI-GEO ]   TSN [ EBI - ARRAY_EXPRESS ]   TSN [ SEEK ]   TSN [ MEM ]
Gene Expression Viewer (FireBrowse)TSN [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)7247
GTEX Portal (Tissue expression)TSN
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ15631   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ15631  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ15631
Splice isoforms : SwissVarQ15631
Catalytic activity : Enzyme3.1.-.- [ Enzyme-Expasy ]   3.1.-.-3.1.-.- [ IntEnz-EBI ]   3.1.-.- [ BRENDA ]   3.1.-.- [ KEGG ]   
PhosPhoSitePlusQ15631
Domains : Interpro (EBI)Translin    Translin_C    Translin_fam    Translin_N   
Domain families : Pfam (Sanger)Translin (PF01997)   
Domain families : Pfam (NCBI)pfam01997   
Conserved Domain (NCBI)TSN
DMDM Disease mutations7247
Blocks (Seattle)TSN
PDB (SRS)1J1J    3PJA    3QB5    4WYV   
PDB (PDBSum)1J1J    3PJA    3QB5    4WYV   
PDB (IMB)1J1J    3PJA    3QB5    4WYV   
PDB (RSDB)1J1J    3PJA    3QB5    4WYV   
Structural Biology KnowledgeBase1J1J    3PJA    3QB5    4WYV   
SCOP (Structural Classification of Proteins)1J1J    3PJA    3QB5    4WYV   
CATH (Classification of proteins structures)1J1J    3PJA    3QB5    4WYV   
SuperfamilyQ15631
Human Protein AtlasENSG00000211460
Peptide AtlasQ15631
HPRD08993
IPIIPI00018768   IPI00922875   IPI00917623   IPI00916061   
Protein Interaction databases
DIP (DOE-UCLA)Q15631
IntAct (EBI)Q15631
FunCoupENSG00000211460
BioGRIDTSN
STRING (EMBL)TSN
ZODIACTSN
Ontologies - Pathways
QuickGOQ15631
Ontology : AmiGODNA binding  single-stranded DNA binding  mRNA binding  endonuclease activity  protein binding  nucleus  cytosol  DNA recombination  RNA metabolic process  gene silencing by RNA  protein complex binding  identical protein binding  sequence-specific DNA binding  nucleic acid phosphodiester bond hydrolysis  
Ontology : EGO-EBIDNA binding  single-stranded DNA binding  mRNA binding  endonuclease activity  protein binding  nucleus  cytosol  DNA recombination  RNA metabolic process  gene silencing by RNA  protein complex binding  identical protein binding  sequence-specific DNA binding  nucleic acid phosphodiester bond hydrolysis  
NDEx NetworkTSN
Atlas of Cancer Signalling NetworkTSN
Wikipedia pathwaysTSN
Orthology - Evolution
OrthoDB7247
GeneTree (enSembl)ENSG00000211460
Phylogenetic Trees/Animal Genes : TreeFamTSN
HOVERGENQ15631
HOGENOMQ15631
Homologs : HomoloGeneTSN
Homology/Alignments : Family Browser (UCSC)TSN
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTSN [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TSN
dbVarTSN
ClinVarTSN
1000_GenomesTSN 
Exome Variant ServerTSN
ExAC (Exome Aggregation Consortium)TSN (select the gene name)
Genetic variants : HAPMAP7247
Genomic Variants (DGV)TSN [DGVbeta]
DECIPHERTSN [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTSN 
Mutations
ICGC Data PortalTSN 
TCGA Data PortalTSN 
Broad Tumor PortalTSN
OASIS PortalTSN [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTSN  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDTSN
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch TSN
DgiDB (Drug Gene Interaction Database)TSN
DoCM (Curated mutations)TSN (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)TSN (select a term)
intoGenTSN
Cancer3DTSN(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM600575   
Orphanet
MedgenTSN
Genetic Testing Registry TSN
NextProtQ15631 [Medical]
TSGene7247
GENETestsTSN
Target ValidationTSN
Huge Navigator TSN [HugePedia]
snp3D : Map Gene to Disease7247
BioCentury BCIQTSN
ClinGenTSN
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD7247
Chemical/Pharm GKB GenePA37047
Clinical trialTSN
Miscellaneous
canSAR (ICR)TSN (select the gene name)
Probes
Litterature
PubMed49 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTSN
EVEXTSN
GoPubMedTSN
iHOPTSN
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Jun 7 13:01:07 CEST 2017

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