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TSPAN14 (tetraspanin 14)

Identity

Alias (NCBI)DC-TM4F2
TM4SF14
tspan-14
HGNC (Hugo) TSPAN14
HGNC Alias symbDC-TM4F2
MGC11352
HGNC Previous nameTM4SF14
HGNC Previous nametransmembrane 4 superfamily member 14
LocusID (NCBI) 81619
Atlas_Id 51434
Location 10q23.1  [Link to chromosome band 10q23]
Location_base_pair Starts at 80454265 and ends at 80522630 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
ABCC5 (3q27.1) / TSPAN14 (10q23.1)GRHL2 (8q22.3) / TSPAN14 (10q23.1)MTMR10 (15q13.3) / TSPAN14 (10q23.1)
SHH (7q36.3) / TSPAN14 (10q23.1)SNN (16p13.13) / TSPAN14 (10q23.1)TSPAN14 (10q23.1) / DYDC2 (10q23.1)
TSPAN14 (10q23.1) / GNB2 (7q22.1)TSPAN14 (10q23.1) / HLA-E (6p21.33)TSPAN14 (10q23.1) / SFTPD (10q22.3)
TSPAN14 (10q23.1) / TMEM254 (10q22.3)TSPAN14 (10q23.1) / TSPAN14 (10q23.1)TSPAN14 (10q23.1) / YWHAH (22q12.3)
GRHL2 8q22.3 / TSPAN14 10q23.1TSPAN14 10q23.1 / DYDC2 10q23.1TSPAN14 10q23.1 / SFTPD 10q22.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)TSPAN14   23303
Cards
Entrez_Gene (NCBI)TSPAN14    tetraspanin 14
AliasesDC-TM4F2; TM4SF14; tspan-14
GeneCards (Weizmann)TSPAN14
Ensembl hg19 (Hinxton)ENSG00000108219 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000108219 [Gene_View]  ENSG00000108219 [Sequence]  chr10:80454265-80522630 [Contig_View]  TSPAN14 [Vega]
ICGC DataPortalENSG00000108219
TCGA cBioPortalTSPAN14
AceView (NCBI)TSPAN14
Genatlas (Paris)TSPAN14
SOURCE (Princeton)TSPAN14
Genetics Home Reference (NIH)TSPAN14
Genomic and cartography
GoldenPath hg38 (UCSC)TSPAN14  -     chr10:80454265-80522630 +  10q23.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TSPAN14  -     10q23.1   [Description]    (hg19-Feb_2009)
GoldenPathTSPAN14 - 10q23.1 [CytoView hg19]  TSPAN14 - 10q23.1 [CytoView hg38]
ImmunoBaseENSG00000108219
Genome Data Viewer NCBITSPAN14 [Mapview hg19]  
Gene and transcription
Genbank (Entrez)AF311903 AI223955 AK025157 AK026621 AK055330
RefSeq transcript (Entrez)NM_001128309 NM_001351266 NM_001351267 NM_001351268 NM_001351269 NM_001351270 NM_001351271 NM_001351272 NM_030927
Consensus coding sequences : CCDS (NCBI)TSPAN14
Gene ExpressionTSPAN14 [ NCBI-GEO ]   TSPAN14 [ EBI - ARRAY_EXPRESS ]   TSPAN14 [ SEEK ]   TSPAN14 [ MEM ]
Gene Expression Viewer (FireBrowse)TSPAN14 [ Firebrowse - Broad ]
GenevisibleExpression of TSPAN14 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)81619
GTEX Portal (Tissue expression)TSPAN14
Human Protein AtlasENSG00000108219-TSPAN14 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8NG11   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8NG11  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8NG11
PhosPhoSitePlusQ8NG11
Domaine pattern : Prosite (Expaxy)TM4_1 (PS00421)   
Domains : Interpro (EBI)Tetraspanin    Tetraspanin/Peripherin    Tetraspanin_CS    Tetraspanin_EC2_sf   
Domain families : Pfam (Sanger)Tetraspanin (PF00335)   
Domain families : Pfam (NCBI)pfam00335   
Conserved Domain (NCBI)TSPAN14
SuperfamilyQ8NG11
AlphaFold pdb e-kbQ8NG11   
Human Protein Atlas [tissue]ENSG00000108219-TSPAN14 [tissue]
HPRD18196
Protein Interaction databases
DIP (DOE-UCLA)Q8NG11
IntAct (EBI)Q8NG11
BioGRIDTSPAN14
STRING (EMBL)TSPAN14
ZODIACTSPAN14
Ontologies - Pathways
QuickGOQ8NG11
Ontology : AmiGOprotein binding  endoplasmic reticulum lumen  plasma membrane  plasma membrane  integral component of plasma membrane  cell surface  enzyme binding  specific granule membrane  neutrophil degranulation  positive regulation of Notch signaling pathway  protein maturation  tertiary granule membrane  protein localization to plasma membrane  tetraspanin-enriched microdomain  amyloid fibril formation  
Ontology : EGO-EBIprotein binding  endoplasmic reticulum lumen  plasma membrane  plasma membrane  integral component of plasma membrane  cell surface  enzyme binding  specific granule membrane  neutrophil degranulation  positive regulation of Notch signaling pathway  protein maturation  tertiary granule membrane  protein localization to plasma membrane  tetraspanin-enriched microdomain  amyloid fibril formation  
NDEx NetworkTSPAN14
Atlas of Cancer Signalling NetworkTSPAN14
Wikipedia pathwaysTSPAN14
Orthology - Evolution
OrthoDB81619
GeneTree (enSembl)ENSG00000108219
Phylogenetic Trees/Animal Genes : TreeFamTSPAN14
Homologs : HomoloGeneTSPAN14
Homology/Alignments : Family Browser (UCSC)TSPAN14
Gene fusions - Rearrangements
Fusion : MitelmanGRHL2/TSPAN14 [8q22.3/10q23.1]  
Fusion : MitelmanTSPAN14/DYDC2 [10q23.1/10q23.1]  
Fusion : MitelmanTSPAN14/HLA-E [10q23.1/6p21.33]  
Fusion : MitelmanTSPAN14/SFTPD [10q23.1/10q22.3]  
Fusion : QuiverTSPAN14
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTSPAN14 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TSPAN14
dbVarTSPAN14
ClinVarTSPAN14
MonarchTSPAN14
1000_GenomesTSPAN14 
Exome Variant ServerTSPAN14
GNOMAD BrowserENSG00000108219
Varsome BrowserTSPAN14
ACMGTSPAN14 variants
VarityQ8NG11
Genomic Variants (DGV)TSPAN14 [DGVbeta]
DECIPHERTSPAN14 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTSPAN14 
Mutations
ICGC Data PortalTSPAN14 
TCGA Data PortalTSPAN14 
Broad Tumor PortalTSPAN14
OASIS PortalTSPAN14 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTSPAN14  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DTSPAN14
Mutations and Diseases : HGMDTSPAN14
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaTSPAN14
DgiDB (Drug Gene Interaction Database)TSPAN14
DoCM (Curated mutations)TSPAN14
CIViC (Clinical Interpretations of Variants in Cancer)TSPAN14
Cancer3DTSPAN14
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
DisGeNETTSPAN14
MedgenTSPAN14
Genetic Testing Registry TSPAN14
NextProtQ8NG11 [Medical]
GENETestsTSPAN14
Target ValidationTSPAN14
Huge Navigator TSPAN14 [HugePedia]
ClinGenTSPAN14
Clinical trials, drugs, therapy
MyCancerGenomeTSPAN14
Protein Interactions : CTDTSPAN14
Pharm GKB GenePA128394731
PharosQ8NG11
Clinical trialTSPAN14
Miscellaneous
canSAR (ICR)TSPAN14
HarmonizomeTSPAN14
DataMed IndexTSPAN14
Probes
Litterature
PubMed16 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXTSPAN14
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 15:36:38 CEST 2021

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