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TSPAN3 (tetraspanin 3)

Identity

Alias (NCBI)TM4-A
TM4SF8
TSPAN-3
HGNC (Hugo) TSPAN3
HGNC Alias symbTM4-A
TSPAN-3
HGNC Previous nameTM4SF8
HGNC Previous nametransmembrane 4 superfamily member 8
LocusID (NCBI) 10099
Atlas_Id 55815
Location 15q24.3  [Link to chromosome band 15q24]
Location_base_pair Starts at 77041404 and ends at 77071109 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
ANKH (5p15.2) / TSPAN3 (15q24.3)MICU1 (10q22.1) / TSPAN3 (15q24.3)PAM16 (16p13.3) / TSPAN3 (15q24.3)
TSPAN3 (15q24.3) / CFB (6p21.33)TSPAN3 (15q24.3) / FLRT2 (14q31.3)TSPAN3 (15q24.3) / TSPAN3 (15q24.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)TSPAN3   17752
Cards
Entrez_Gene (NCBI)TSPAN3    tetraspanin 3
AliasesTM4-A; TM4SF8; TSPAN-3
GeneCards (Weizmann)TSPAN3
Ensembl hg19 (Hinxton)ENSG00000140391 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000140391 [Gene_View]  ENSG00000140391 [Sequence]  chr15:77041404-77071109 [Contig_View]  TSPAN3 [Vega]
ICGC DataPortalENSG00000140391
TCGA cBioPortalTSPAN3
AceView (NCBI)TSPAN3
Genatlas (Paris)TSPAN3
SOURCE (Princeton)TSPAN3
Genetics Home Reference (NIH)TSPAN3
Genomic and cartography
GoldenPath hg38 (UCSC)TSPAN3  -     chr15:77041404-77071109 -  15q24.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TSPAN3  -     15q24.3   [Description]    (hg19-Feb_2009)
GoldenPathTSPAN3 - 15q24.3 [CytoView hg19]  TSPAN3 - 15q24.3 [CytoView hg38]
ImmunoBaseENSG00000140391
Genome Data Viewer NCBITSPAN3 [Mapview hg19]  
OMIM613134   
Gene and transcription
Genbank (Entrez)AA554982 AF054840 AF133423 AK001305 AK001310
RefSeq transcript (Entrez)NM_001168412 NM_005724 NM_198902
Consensus coding sequences : CCDS (NCBI)TSPAN3
Gene ExpressionTSPAN3 [ NCBI-GEO ]   TSPAN3 [ EBI - ARRAY_EXPRESS ]   TSPAN3 [ SEEK ]   TSPAN3 [ MEM ]
Gene Expression Viewer (FireBrowse)TSPAN3 [ Firebrowse - Broad ]
GenevisibleExpression of TSPAN3 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)10099
GTEX Portal (Tissue expression)TSPAN3
Human Protein AtlasENSG00000140391-TSPAN3 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtO60637   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO60637  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO60637
PhosPhoSitePlusO60637
Domaine pattern : Prosite (Expaxy)TM4_1 (PS00421)   
Domains : Interpro (EBI)Tetraspanin    Tetraspanin/Peripherin    Tetraspanin_CS    Tetraspanin_EC2_sf   
Domain families : Pfam (Sanger)Tetraspanin (PF00335)   
Domain families : Pfam (NCBI)pfam00335   
Conserved Domain (NCBI)TSPAN3
SuperfamilyO60637
AlphaFold pdb e-kbO60637   
Human Protein Atlas [tissue]ENSG00000140391-TSPAN3 [tissue]
HPRD15512
Protein Interaction databases
DIP (DOE-UCLA)O60637
IntAct (EBI)O60637
BioGRIDTSPAN3
STRING (EMBL)TSPAN3
ZODIACTSPAN3
Ontologies - Pathways
QuickGOO60637
Ontology : AmiGOmolecular_function  integral component of plasma membrane  biological_process  extracellular exosome  
Ontology : EGO-EBImolecular_function  integral component of plasma membrane  biological_process  extracellular exosome  
NDEx NetworkTSPAN3
Atlas of Cancer Signalling NetworkTSPAN3
Wikipedia pathwaysTSPAN3
Orthology - Evolution
OrthoDB10099
GeneTree (enSembl)ENSG00000140391
Phylogenetic Trees/Animal Genes : TreeFamTSPAN3
Homologs : HomoloGeneTSPAN3
Homology/Alignments : Family Browser (UCSC)TSPAN3
Gene fusions - Rearrangements
Fusion : QuiverTSPAN3
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTSPAN3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TSPAN3
dbVarTSPAN3
ClinVarTSPAN3
MonarchTSPAN3
1000_GenomesTSPAN3 
Exome Variant ServerTSPAN3
GNOMAD BrowserENSG00000140391
Varsome BrowserTSPAN3
ACMGTSPAN3 variants
VarityO60637
Genomic Variants (DGV)TSPAN3 [DGVbeta]
DECIPHERTSPAN3 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTSPAN3 
Mutations
ICGC Data PortalTSPAN3 
TCGA Data PortalTSPAN3 
Broad Tumor PortalTSPAN3
OASIS PortalTSPAN3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTSPAN3  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DTSPAN3
Mutations and Diseases : HGMDTSPAN3
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaTSPAN3
DgiDB (Drug Gene Interaction Database)TSPAN3
DoCM (Curated mutations)TSPAN3
CIViC (Clinical Interpretations of Variants in Cancer)TSPAN3
Cancer3DTSPAN3
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM613134   
Orphanet
DisGeNETTSPAN3
MedgenTSPAN3
Genetic Testing Registry TSPAN3
NextProtO60637 [Medical]
GENETestsTSPAN3
Target ValidationTSPAN3
Huge Navigator TSPAN3 [HugePedia]
ClinGenTSPAN3
Clinical trials, drugs, therapy
MyCancerGenomeTSPAN3
Protein Interactions : CTDTSPAN3
Pharm GKB GenePA134913500
PharosO60637
Clinical trialTSPAN3
Miscellaneous
canSAR (ICR)TSPAN3
HarmonizomeTSPAN3
DataMed IndexTSPAN3
Probes
Litterature
PubMed23 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXTSPAN3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Mon Oct 4 15:36:39 CEST 2021

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