Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

TSPAN4 (tetraspanin 4)

Identity

Alias_namesTM4SF7
transmembrane 4 superfamily member 7
Alias_symbol (synonym)NAG-2
TSPAN-4
TETRASPAN
Other aliasNAG2
HGNC (Hugo) TSPAN4
LocusID (NCBI) 7106
Atlas_Id 52799
Location 11p15.5  [Link to chromosome band 11p15]
Location_base_pair Starts at 844081 and ends at 867116 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
LOC100507412 (-) / TSPAN4 (11p15.5)RNF126 (19p13.3) / TSPAN4 (11p15.5)TBC1D22A (22q13.31) / TSPAN4 (11p15.5)
TSPAN4 (11p15.5) / EPS8L2 (11p15.5)TSPAN4 (11p15.5) / TSPAN4 (11p15.5)TSPAN4 11p15.5 / EPS8L2 11p15.5

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)TSPAN4   11859
Cards
Entrez_Gene (NCBI)TSPAN4  7106  tetraspanin 4
AliasesNAG-2; NAG2; TETRASPAN; TM4SF7; 
TSPAN-4
GeneCards (Weizmann)TSPAN4
Ensembl hg19 (Hinxton)ENSG00000214063 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000214063 [Gene_View]  chr11:844081-867116 [Contig_View]  TSPAN4 [Vega]
ICGC DataPortalENSG00000214063
TCGA cBioPortalTSPAN4
AceView (NCBI)TSPAN4
Genatlas (Paris)TSPAN4
WikiGenes7106
SOURCE (Princeton)TSPAN4
Genetics Home Reference (NIH)TSPAN4
Genomic and cartography
GoldenPath hg38 (UCSC)TSPAN4  -     chr11:844081-867116 +  11p15.5   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TSPAN4  -     11p15.5   [Description]    (hg19-Feb_2009)
EnsemblTSPAN4 - 11p15.5 [CytoView hg19]  TSPAN4 - 11p15.5 [CytoView hg38]
Mapping of homologs : NCBITSPAN4 [Mapview hg19]  TSPAN4 [Mapview hg38]
OMIM602644   
Gene and transcription
Genbank (Entrez)AF022813 AF054841 AK054788 AK095212 AK126456
RefSeq transcript (Entrez)NM_001025234 NM_001025235 NM_001025236 NM_001025237 NM_001025238 NM_001025239 NM_003271
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)TSPAN4
Cluster EST : UnigeneHs.654836 [ NCBI ]
CGAP (NCI)Hs.654836
Alternative Splicing GalleryENSG00000214063
Gene ExpressionTSPAN4 [ NCBI-GEO ]   TSPAN4 [ EBI - ARRAY_EXPRESS ]   TSPAN4 [ SEEK ]   TSPAN4 [ MEM ]
Gene Expression Viewer (FireBrowse)TSPAN4 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)7106
GTEX Portal (Tissue expression)TSPAN4
Protein : pattern, domain, 3D structure
UniProt/SwissProtO14817   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO14817  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO14817
Splice isoforms : SwissVarO14817
PhosPhoSitePlusO14817
Domaine pattern : Prosite (Expaxy)TM4_1 (PS00421)   
Domains : Interpro (EBI)Tetraspanin    Tetraspanin/Peripherin    Tetraspanin_CS    Tetraspanin_EC2   
Domain families : Pfam (Sanger)Tetraspannin (PF00335)   
Domain families : Pfam (NCBI)pfam00335   
Conserved Domain (NCBI)TSPAN4
DMDM Disease mutations7106
Blocks (Seattle)TSPAN4
SuperfamilyO14817
Human Protein AtlasENSG00000214063
Peptide AtlasO14817
HPRD04033
IPIIPI00024174   IPI00916272   IPI00978173   IPI00976403   IPI00619895   IPI00976972   IPI00973982   IPI00917093   
Protein Interaction databases
DIP (DOE-UCLA)O14817
IntAct (EBI)O14817
FunCoupENSG00000214063
BioGRIDTSPAN4
STRING (EMBL)TSPAN4
ZODIACTSPAN4
Ontologies - Pathways
QuickGOO14817
Ontology : AmiGOantigen binding  integrin binding  protein binding  plasma membrane  integral component of plasma membrane  focal adhesion  protein complex assembly  cell surface receptor signaling pathway  vesicle  
Ontology : EGO-EBIantigen binding  integrin binding  protein binding  plasma membrane  integral component of plasma membrane  focal adhesion  protein complex assembly  cell surface receptor signaling pathway  vesicle  
NDEx NetworkTSPAN4
Atlas of Cancer Signalling NetworkTSPAN4
Wikipedia pathwaysTSPAN4
Orthology - Evolution
OrthoDB7106
GeneTree (enSembl)ENSG00000214063
Phylogenetic Trees/Animal Genes : TreeFamTSPAN4
HOVERGENO14817
HOGENOMO14817
Homologs : HomoloGeneTSPAN4
Homology/Alignments : Family Browser (UCSC)TSPAN4
Gene fusions - Rearrangements
Fusion : MitelmanTSPAN4/EPS8L2 [11p15.5/11p15.5]  
Fusion: TCGATSPAN4 11p15.5 EPS8L2 11p15.5 LUAD
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTSPAN4 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TSPAN4
dbVarTSPAN4
ClinVarTSPAN4
1000_GenomesTSPAN4 
Exome Variant ServerTSPAN4
ExAC (Exome Aggregation Consortium)TSPAN4 (select the gene name)
Genetic variants : HAPMAP7106
Genomic Variants (DGV)TSPAN4 [DGVbeta]
DECIPHERTSPAN4 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTSPAN4 
Mutations
ICGC Data PortalTSPAN4 
TCGA Data PortalTSPAN4 
Broad Tumor PortalTSPAN4
OASIS PortalTSPAN4 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTSPAN4  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDTSPAN4
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch TSPAN4
DgiDB (Drug Gene Interaction Database)TSPAN4
DoCM (Curated mutations)TSPAN4 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)TSPAN4 (select a term)
intoGenTSPAN4
Cancer3DTSPAN4(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM602644   
Orphanet
MedgenTSPAN4
Genetic Testing Registry TSPAN4
NextProtO14817 [Medical]
TSGene7106
GENETestsTSPAN4
Huge Navigator TSPAN4 [HugePedia]
snp3D : Map Gene to Disease7106
BioCentury BCIQTSPAN4
ClinGenTSPAN4
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD7106
Chemical/Pharm GKB GenePA36560
Clinical trialTSPAN4
Miscellaneous
canSAR (ICR)TSPAN4 (select the gene name)
Probes
Litterature
PubMed18 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTSPAN4
EVEXTSPAN4
GoPubMedTSPAN4
iHOPTSPAN4
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Fri May 19 12:42:33 CEST 2017

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.