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TSPAN5 (tetraspanin 5)

Identity

Alias (NCBI)NET-4
NET4
TM4SF9
TSPAN-5
HGNC (Hugo) TSPAN5
HGNC Alias symbTspan-5
NET-4
HGNC Previous nameTM4SF9
HGNC Previous nametransmembrane 4 superfamily member 9
LocusID (NCBI) 10098
Atlas_Id 57347
Location 4q23  [Link to chromosome band 4q23]
Location_base_pair Starts at 98470367 and ends at 98658611 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
FGG (4q31.3) / TSPAN5 (4q23)TSPAN5 (4q23) / ADH4 (4q23)TSPAN5 (4q23) / EIF4E (4q23)
TSPAN5 (4q23) / METAP1 (4q23)TSPAN5 (4q23) / NACA (12q13.3)TSPAN5 (4q23) / PKD2 (4q22.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)TSPAN5   17753
Cards
Entrez_Gene (NCBI)TSPAN5    tetraspanin 5
AliasesNET-4; NET4; TM4SF9; TSPAN-5
GeneCards (Weizmann)TSPAN5
Ensembl hg19 (Hinxton)ENSG00000168785 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000168785 [Gene_View]  ENSG00000168785 [Sequence]  chr4:98470367-98658611 [Contig_View]  TSPAN5 [Vega]
ICGC DataPortalENSG00000168785
TCGA cBioPortalTSPAN5
AceView (NCBI)TSPAN5
Genatlas (Paris)TSPAN5
SOURCE (Princeton)TSPAN5
Genetics Home Reference (NIH)TSPAN5
Genomic and cartography
GoldenPath hg38 (UCSC)TSPAN5  -     chr4:98470367-98658611 -  4q23   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TSPAN5  -     4q23   [Description]    (hg19-Feb_2009)
GoldenPathTSPAN5 - 4q23 [CytoView hg19]  TSPAN5 - 4q23 [CytoView hg38]
ImmunoBaseENSG00000168785
Genome Data Viewer NCBITSPAN5 [Mapview hg19]  
OMIM613136   
Gene and transcription
Genbank (Entrez)AF065389 AI089708 AK055659 AK126702 AK295385
RefSeq transcript (Entrez)NM_005723
Consensus coding sequences : CCDS (NCBI)TSPAN5
Gene ExpressionTSPAN5 [ NCBI-GEO ]   TSPAN5 [ EBI - ARRAY_EXPRESS ]   TSPAN5 [ SEEK ]   TSPAN5 [ MEM ]
Gene Expression Viewer (FireBrowse)TSPAN5 [ Firebrowse - Broad ]
GenevisibleExpression of TSPAN5 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)10098
GTEX Portal (Tissue expression)TSPAN5
Human Protein AtlasENSG00000168785-TSPAN5 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP62079   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP62079  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP62079
PhosPhoSitePlusP62079
Domaine pattern : Prosite (Expaxy)TM4_1 (PS00421)   
Domains : Interpro (EBI)Tetraspanin    Tetraspanin/Peripherin    Tetraspanin_CS    Tetraspanin_EC2_sf   
Domain families : Pfam (Sanger)Tetraspanin (PF00335)   
Domain families : Pfam (NCBI)pfam00335   
Conserved Domain (NCBI)TSPAN5
SuperfamilyP62079
AlphaFold pdb e-kbP62079   
Human Protein Atlas [tissue]ENSG00000168785-TSPAN5 [tissue]
Protein Interaction databases
DIP (DOE-UCLA)P62079
IntAct (EBI)P62079
BioGRIDTSPAN5
STRING (EMBL)TSPAN5
ZODIACTSPAN5
Ontologies - Pathways
QuickGOP62079
Ontology : AmiGOprotein binding  endoplasmic reticulum lumen  plasma membrane  plasma membrane  integral component of plasma membrane  enzyme binding  positive regulation of Notch signaling pathway  protein maturation  protein maturation  protein localization to plasma membrane  protein localization to plasma membrane  amyloid fibril formation  
Ontology : EGO-EBIprotein binding  endoplasmic reticulum lumen  plasma membrane  plasma membrane  integral component of plasma membrane  enzyme binding  positive regulation of Notch signaling pathway  protein maturation  protein maturation  protein localization to plasma membrane  protein localization to plasma membrane  amyloid fibril formation  
NDEx NetworkTSPAN5
Atlas of Cancer Signalling NetworkTSPAN5
Wikipedia pathwaysTSPAN5
Orthology - Evolution
OrthoDB10098
GeneTree (enSembl)ENSG00000168785
Phylogenetic Trees/Animal Genes : TreeFamTSPAN5
Homologs : HomoloGeneTSPAN5
Homology/Alignments : Family Browser (UCSC)TSPAN5
Gene fusions - Rearrangements
Fusion : QuiverTSPAN5
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTSPAN5 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TSPAN5
dbVarTSPAN5
ClinVarTSPAN5
MonarchTSPAN5
1000_GenomesTSPAN5 
Exome Variant ServerTSPAN5
GNOMAD BrowserENSG00000168785
Varsome BrowserTSPAN5
ACMGTSPAN5 variants
VarityP62079
Genomic Variants (DGV)TSPAN5 [DGVbeta]
DECIPHERTSPAN5 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTSPAN5 
Mutations
ICGC Data PortalTSPAN5 
TCGA Data PortalTSPAN5 
Broad Tumor PortalTSPAN5
OASIS PortalTSPAN5 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTSPAN5  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DTSPAN5
Mutations and Diseases : HGMDTSPAN5
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaTSPAN5
DgiDB (Drug Gene Interaction Database)TSPAN5
DoCM (Curated mutations)TSPAN5
CIViC (Clinical Interpretations of Variants in Cancer)TSPAN5
Cancer3DTSPAN5
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM613136   
Orphanet
DisGeNETTSPAN5
MedgenTSPAN5
Genetic Testing Registry TSPAN5
NextProtP62079 [Medical]
GENETestsTSPAN5
Target ValidationTSPAN5
Huge Navigator TSPAN5 [HugePedia]
ClinGenTSPAN5
Clinical trials, drugs, therapy
MyCancerGenomeTSPAN5
Protein Interactions : CTDTSPAN5
Pharm GKB GenePA134864098
PharosP62079
Clinical trialTSPAN5
Miscellaneous
canSAR (ICR)TSPAN5
HarmonizomeTSPAN5
DataMed IndexTSPAN5
Probes
Litterature
PubMed22 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXTSPAN5
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 15:36:40 CEST 2021

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