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TSPAN5 (tetraspanin 5)

Identity

Alias_namesTM4SF9
transmembrane 4 superfamily member 9
Alias_symbol (synonym)Tspan-5
NET-4
Other aliasNET4
TSPAN-5
HGNC (Hugo) TSPAN5
LocusID (NCBI) 10098
Atlas_Id 75239
Location 4q23  [Link to chromosome band 4q23]
Location_base_pair Starts at 98470367 and ends at 98658661 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
FGG (4q31.3) / TSPAN5 (4q23)TSPAN5 (4q23) / ADH4 (4q23)TSPAN5 (4q23) / EIF4E (4q23)
TSPAN5 (4q23) / METAP1 (4q23)TSPAN5 (4q23) / NACA (12q13.3)TSPAN5 (4q23) / PKD2 (4q22.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)TSPAN5   17753
Cards
Entrez_Gene (NCBI)TSPAN5  10098  tetraspanin 5
AliasesNET-4; NET4; TM4SF9; TSPAN-5
GeneCards (Weizmann)TSPAN5
Ensembl hg19 (Hinxton)ENSG00000168785 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000168785 [Gene_View]  chr4:98470367-98658661 [Contig_View]  TSPAN5 [Vega]
ICGC DataPortalENSG00000168785
TCGA cBioPortalTSPAN5
AceView (NCBI)TSPAN5
Genatlas (Paris)TSPAN5
WikiGenes10098
SOURCE (Princeton)TSPAN5
Genetics Home Reference (NIH)TSPAN5
Genomic and cartography
GoldenPath hg38 (UCSC)TSPAN5  -     chr4:98470367-98658661 -  4q23   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TSPAN5  -     4q23   [Description]    (hg19-Feb_2009)
EnsemblTSPAN5 - 4q23 [CytoView hg19]  TSPAN5 - 4q23 [CytoView hg38]
Mapping of homologs : NCBITSPAN5 [Mapview hg19]  TSPAN5 [Mapview hg38]
OMIM613136   
Gene and transcription
Genbank (Entrez)AF065389 AI089708 AK055659 AK126702 AK295385
RefSeq transcript (Entrez)NM_005723
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)TSPAN5
Cluster EST : UnigeneHs.118118 [ NCBI ]
CGAP (NCI)Hs.118118
Alternative Splicing GalleryENSG00000168785
Gene ExpressionTSPAN5 [ NCBI-GEO ]   TSPAN5 [ EBI - ARRAY_EXPRESS ]   TSPAN5 [ SEEK ]   TSPAN5 [ MEM ]
Gene Expression Viewer (FireBrowse)TSPAN5 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)10098
GTEX Portal (Tissue expression)TSPAN5
Human Protein AtlasENSG00000168785-TSPAN5 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP62079   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP62079  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP62079
Splice isoforms : SwissVarP62079
PhosPhoSitePlusP62079
Domaine pattern : Prosite (Expaxy)TM4_1 (PS00421)   
Domains : Interpro (EBI)Tetraspanin    Tetraspanin/Peripherin    Tetraspanin_CS    Tetraspanin_EC2   
Domain families : Pfam (Sanger)Tetraspannin (PF00335)   
Domain families : Pfam (NCBI)pfam00335   
Conserved Domain (NCBI)TSPAN5
DMDM Disease mutations10098
Blocks (Seattle)TSPAN5
SuperfamilyP62079
Human Protein Atlas [tissue]ENSG00000168785-TSPAN5 [tissue]
Peptide AtlasP62079
HPRD15513
IPIIPI00030914   IPI00964783   IPI00965786   IPI00965526   IPI00966093   IPI00964002   IPI00964300   
Protein Interaction databases
DIP (DOE-UCLA)P62079
IntAct (EBI)P62079
FunCoupENSG00000168785
BioGRIDTSPAN5
STRING (EMBL)TSPAN5
ZODIACTSPAN5
Ontologies - Pathways
QuickGOP62079
Ontology : AmiGOplasma membrane  integral component of plasma membrane  enzyme binding  positive regulation of Notch signaling pathway  protein maturation  establishment of protein localization to plasma membrane  
Ontology : EGO-EBIplasma membrane  integral component of plasma membrane  enzyme binding  positive regulation of Notch signaling pathway  protein maturation  establishment of protein localization to plasma membrane  
NDEx NetworkTSPAN5
Atlas of Cancer Signalling NetworkTSPAN5
Wikipedia pathwaysTSPAN5
Orthology - Evolution
OrthoDB10098
GeneTree (enSembl)ENSG00000168785
Phylogenetic Trees/Animal Genes : TreeFamTSPAN5
HOVERGENP62079
HOGENOMP62079
Homologs : HomoloGeneTSPAN5
Homology/Alignments : Family Browser (UCSC)TSPAN5
Gene fusions - Rearrangements
Tumor Fusion PortalTSPAN5
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTSPAN5 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TSPAN5
dbVarTSPAN5
ClinVarTSPAN5
1000_GenomesTSPAN5 
Exome Variant ServerTSPAN5
ExAC (Exome Aggregation Consortium)ENSG00000168785
GNOMAD BrowserENSG00000168785
Genetic variants : HAPMAP10098
Genomic Variants (DGV)TSPAN5 [DGVbeta]
DECIPHERTSPAN5 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTSPAN5 
Mutations
ICGC Data PortalTSPAN5 
TCGA Data PortalTSPAN5 
Broad Tumor PortalTSPAN5
OASIS PortalTSPAN5 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTSPAN5  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDTSPAN5
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch TSPAN5
DgiDB (Drug Gene Interaction Database)TSPAN5
DoCM (Curated mutations)TSPAN5 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)TSPAN5 (select a term)
intoGenTSPAN5
Cancer3DTSPAN5(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM613136   
Orphanet
DisGeNETTSPAN5
MedgenTSPAN5
Genetic Testing Registry TSPAN5
NextProtP62079 [Medical]
TSGene10098
GENETestsTSPAN5
Target ValidationTSPAN5
Huge Navigator TSPAN5 [HugePedia]
snp3D : Map Gene to Disease10098
BioCentury BCIQTSPAN5
ClinGenTSPAN5
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD10098
Chemical/Pharm GKB GenePA134864098
Clinical trialTSPAN5
Miscellaneous
canSAR (ICR)TSPAN5 (select the gene name)
Probes
Litterature
PubMed12 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTSPAN5
EVEXTSPAN5
GoPubMedTSPAN5
iHOPTSPAN5
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Nov 20 20:20:03 CET 2017

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