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TSPAN6 (tetraspanin 6)

Identity

Alias (NCBI)T245
TM4SF6
TSPAN-6
HGNC (Hugo) TSPAN6
HGNC Alias symbT245
TSPAN-6
HGNC Previous nameTM4SF6
HGNC Previous nametransmembrane 4 superfamily member 6
LocusID (NCBI) 7105
Atlas_Id 75240
Location Xq22.1  [Link to chromosome band Xq22]
Location_base_pair Starts at 100627108 and ends at 100636806 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
TSPAN6 (Xq22.1) / SOX5 (12p12.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)TSPAN6   11858
Cards
Entrez_Gene (NCBI)TSPAN6    tetraspanin 6
AliasesT245; TM4SF6; TSPAN-6
GeneCards (Weizmann)TSPAN6
Ensembl hg19 (Hinxton)ENSG00000000003 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000000003 [Gene_View]  ENSG00000000003 [Sequence]  chrX:100627108-100636806 [Contig_View]  TSPAN6 [Vega]
ICGC DataPortalENSG00000000003
TCGA cBioPortalTSPAN6
AceView (NCBI)TSPAN6
Genatlas (Paris)TSPAN6
SOURCE (Princeton)TSPAN6
Genetics Home Reference (NIH)TSPAN6
Genomic and cartography
GoldenPath hg38 (UCSC)TSPAN6  -     chrX:100627108-100636806 -  Xq22.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TSPAN6  -     Xq22.1   [Description]    (hg19-Feb_2009)
GoldenPathTSPAN6 - Xq22.1 [CytoView hg19]  TSPAN6 - Xq22.1 [CytoView hg38]
ImmunoBaseENSG00000000003
Genome Data Viewer NCBITSPAN6 [Mapview hg19]  
OMIM300191   
Gene and transcription
Genbank (Entrez)AB097016 AB209876 AF043906 AF053453 AF133426
RefSeq transcript (Entrez)NM_001278740 NM_001278741 NM_001278742 NM_001278743 NM_003270
Consensus coding sequences : CCDS (NCBI)TSPAN6
Gene ExpressionTSPAN6 [ NCBI-GEO ]   TSPAN6 [ EBI - ARRAY_EXPRESS ]   TSPAN6 [ SEEK ]   TSPAN6 [ MEM ]
Gene Expression Viewer (FireBrowse)TSPAN6 [ Firebrowse - Broad ]
GenevisibleExpression of TSPAN6 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)7105
GTEX Portal (Tissue expression)TSPAN6
Human Protein AtlasENSG00000000003-TSPAN6 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtO43657   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO43657  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO43657
PhosPhoSitePlusO43657
Domaine pattern : Prosite (Expaxy)TM4_1 (PS00421)   
Domains : Interpro (EBI)Tetraspanin    Tetraspanin/Peripherin    Tetraspanin_CS    Tetraspanin_EC2_sf   
Domain families : Pfam (Sanger)Tetraspanin (PF00335)   
Domain families : Pfam (NCBI)pfam00335   
Conserved Domain (NCBI)TSPAN6
SuperfamilyO43657
AlphaFold pdb e-kbO43657   
Human Protein Atlas [tissue]ENSG00000000003-TSPAN6 [tissue]
HPRD02179
Protein Interaction databases
DIP (DOE-UCLA)O43657
IntAct (EBI)O43657
BioGRIDTSPAN6
STRING (EMBL)TSPAN6
ZODIACTSPAN6
Ontologies - Pathways
QuickGOO43657
Ontology : AmiGOprotein binding  integral component of plasma membrane  negative regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway  positive regulation of I-kappaB kinase/NF-kappaB signaling  extracellular exosome  negative regulation of NIK/NF-kappaB signaling  
Ontology : EGO-EBIprotein binding  integral component of plasma membrane  negative regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway  positive regulation of I-kappaB kinase/NF-kappaB signaling  extracellular exosome  negative regulation of NIK/NF-kappaB signaling  
NDEx NetworkTSPAN6
Atlas of Cancer Signalling NetworkTSPAN6
Wikipedia pathwaysTSPAN6
Orthology - Evolution
OrthoDB7105
GeneTree (enSembl)ENSG00000000003
Phylogenetic Trees/Animal Genes : TreeFamTSPAN6
Homologs : HomoloGeneTSPAN6
Homology/Alignments : Family Browser (UCSC)TSPAN6
Gene fusions - Rearrangements
Fusion : QuiverTSPAN6
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTSPAN6 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TSPAN6
dbVarTSPAN6
ClinVarTSPAN6
MonarchTSPAN6
1000_GenomesTSPAN6 
Exome Variant ServerTSPAN6
GNOMAD BrowserENSG00000000003
Varsome BrowserTSPAN6
ACMGTSPAN6 variants
VarityO43657
Genomic Variants (DGV)TSPAN6 [DGVbeta]
DECIPHERTSPAN6 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTSPAN6 
Mutations
ICGC Data PortalTSPAN6 
TCGA Data PortalTSPAN6 
Broad Tumor PortalTSPAN6
OASIS PortalTSPAN6 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTSPAN6  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DTSPAN6
Mutations and Diseases : HGMDTSPAN6
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaTSPAN6
DgiDB (Drug Gene Interaction Database)TSPAN6
DoCM (Curated mutations)TSPAN6
CIViC (Clinical Interpretations of Variants in Cancer)TSPAN6
Cancer3DTSPAN6
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM300191   
Orphanet
DisGeNETTSPAN6
MedgenTSPAN6
Genetic Testing Registry TSPAN6
NextProtO43657 [Medical]
GENETestsTSPAN6
Target ValidationTSPAN6
Huge Navigator TSPAN6 [HugePedia]
ClinGenTSPAN6
Clinical trials, drugs, therapy
MyCancerGenomeTSPAN6
Protein Interactions : CTDTSPAN6
Pharm GKB GenePA36559
PharosO43657
Clinical trialTSPAN6
Miscellaneous
canSAR (ICR)TSPAN6
HarmonizomeTSPAN6
DataMed IndexTSPAN6
Probes
Litterature
PubMed28 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXTSPAN6
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 16:27:09 CEST 2021

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