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TSPAN6 (tetraspanin 6)

Identity

Alias_namesTM4SF6
transmembrane 4 superfamily member 6
Alias_symbol (synonym)T245
TSPAN-6
Other alias
HGNC (Hugo) TSPAN6
LocusID (NCBI) 7105
Atlas_Id 75240
Location Xq22.1  [Link to chromosome band Xq22]
Location_base_pair Starts at 100627108 and ends at 100636732 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
TSPAN6 (Xq22.1) / SOX5 (12p12.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)TSPAN6   11858
Cards
Entrez_Gene (NCBI)TSPAN6  7105  tetraspanin 6
AliasesT245; TM4SF6; TSPAN-6
GeneCards (Weizmann)TSPAN6
Ensembl hg19 (Hinxton)ENSG00000000003 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000000003 [Gene_View]  chrX:100627108-100636732 [Contig_View]  TSPAN6 [Vega]
ICGC DataPortalENSG00000000003
TCGA cBioPortalTSPAN6
AceView (NCBI)TSPAN6
Genatlas (Paris)TSPAN6
WikiGenes7105
SOURCE (Princeton)TSPAN6
Genetics Home Reference (NIH)TSPAN6
Genomic and cartography
GoldenPath hg38 (UCSC)TSPAN6  -     chrX:100627108-100636732 -  Xq22.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TSPAN6  -     Xq22.1   [Description]    (hg19-Feb_2009)
EnsemblTSPAN6 - Xq22.1 [CytoView hg19]  TSPAN6 - Xq22.1 [CytoView hg38]
Mapping of homologs : NCBITSPAN6 [Mapview hg19]  TSPAN6 [Mapview hg38]
OMIM300191   
Gene and transcription
Genbank (Entrez)AB097016 AB209876 AF043906 AF053453 AF133426
RefSeq transcript (Entrez)NM_001278740 NM_001278741 NM_001278742 NM_001278743 NM_003270
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)TSPAN6
Cluster EST : UnigeneHs.587521 [ NCBI ]
CGAP (NCI)Hs.587521
Alternative Splicing GalleryENSG00000000003
Gene ExpressionTSPAN6 [ NCBI-GEO ]   TSPAN6 [ EBI - ARRAY_EXPRESS ]   TSPAN6 [ SEEK ]   TSPAN6 [ MEM ]
Gene Expression Viewer (FireBrowse)TSPAN6 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)7105
GTEX Portal (Tissue expression)TSPAN6
Protein : pattern, domain, 3D structure
UniProt/SwissProtO43657   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO43657  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO43657
Splice isoforms : SwissVarO43657
PhosPhoSitePlusO43657
Domaine pattern : Prosite (Expaxy)TM4_1 (PS00421)   
Domains : Interpro (EBI)CD81_LEL    Tetraspanin    Tetraspanin/Peripherin    Tetraspanin_CS    Tetraspanin_EC2   
Domain families : Pfam (Sanger)Tetraspannin (PF00335)   
Domain families : Pfam (NCBI)pfam00335   
Conserved Domain (NCBI)TSPAN6
DMDM Disease mutations7105
Blocks (Seattle)TSPAN6
SuperfamilyO43657
Human Protein AtlasENSG00000000003
Peptide AtlasO43657
HPRD02179
IPIIPI00013449   IPI00909503   IPI01014712   
Protein Interaction databases
DIP (DOE-UCLA)O43657
IntAct (EBI)O43657
FunCoupENSG00000000003
BioGRIDTSPAN6
STRING (EMBL)TSPAN6
ZODIACTSPAN6
Ontologies - Pathways
QuickGOO43657
Ontology : AmiGOsignal transducer activity  protein binding  integral component of plasma membrane  cell surface receptor signaling pathway  negative regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway  positive regulation of I-kappaB kinase/NF-kappaB signaling  extracellular exosome  negative regulation of NIK/NF-kappaB signaling  
Ontology : EGO-EBIsignal transducer activity  protein binding  integral component of plasma membrane  cell surface receptor signaling pathway  negative regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway  positive regulation of I-kappaB kinase/NF-kappaB signaling  extracellular exosome  negative regulation of NIK/NF-kappaB signaling  
NDEx NetworkTSPAN6
Atlas of Cancer Signalling NetworkTSPAN6
Wikipedia pathwaysTSPAN6
Orthology - Evolution
OrthoDB7105
GeneTree (enSembl)ENSG00000000003
Phylogenetic Trees/Animal Genes : TreeFamTSPAN6
HOVERGENO43657
HOGENOMO43657
Homologs : HomoloGeneTSPAN6
Homology/Alignments : Family Browser (UCSC)TSPAN6
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTSPAN6 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TSPAN6
dbVarTSPAN6
ClinVarTSPAN6
1000_GenomesTSPAN6 
Exome Variant ServerTSPAN6
ExAC (Exome Aggregation Consortium)TSPAN6 (select the gene name)
Genetic variants : HAPMAP7105
Genomic Variants (DGV)TSPAN6 [DGVbeta]
DECIPHERTSPAN6 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTSPAN6 
Mutations
ICGC Data PortalTSPAN6 
TCGA Data PortalTSPAN6 
Broad Tumor PortalTSPAN6
OASIS PortalTSPAN6 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTSPAN6  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDTSPAN6
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)X-chromosome gene database
BioMutasearch TSPAN6
DgiDB (Drug Gene Interaction Database)TSPAN6
DoCM (Curated mutations)TSPAN6 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)TSPAN6 (select a term)
intoGenTSPAN6
Cancer3DTSPAN6(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM300191   
Orphanet
MedgenTSPAN6
Genetic Testing Registry TSPAN6
NextProtO43657 [Medical]
TSGene7105
GENETestsTSPAN6
Target ValidationTSPAN6
Huge Navigator TSPAN6 [HugePedia]
snp3D : Map Gene to Disease7105
BioCentury BCIQTSPAN6
ClinGenTSPAN6
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD7105
Chemical/Pharm GKB GenePA36559
Clinical trialTSPAN6
Miscellaneous
canSAR (ICR)TSPAN6 (select the gene name)
Probes
Litterature
PubMed23 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTSPAN6
EVEXTSPAN6
GoPubMedTSPAN6
iHOPTSPAN6
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed May 31 15:47:22 CEST 2017

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