TSR3 (TSR3 ribosome maturation factor)

2014-11-01  

Identity

HGNC
LOCATION
16p13.3
LOCUSID
ALIAS
C16orf42,HsTsr3
FUSION GENES

Other Information

Locus ID:

NCBI: 115939
MIM: 617058
HGNC: 14175
Ensembl: ENSG00000007520

Variants:

dbSNP: 115939
ClinVar: 115939
TCGA: ENSG00000007520
COSMIC: TSR3

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000007520ENST00000007390Q9UJK0
ENSG00000007520ENST00000566296H3BQD4

Expression (GTEx)

0
50
100
150

Pathways

PathwaySourceExternal ID
Gene ExpressionREACTOMER-HSA-74160
rRNA processingREACTOMER-HSA-72312
rRNA modification in the nucleus and cytosolREACTOMER-HSA-6790901
rRNA processing in the nucleus and cytosolREACTOMER-HSA-8868773

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
270849492016Ribosome biogenesis factor Tsr3 is the aminocarboxypropyl transferase responsible for 18S rRNA hypermodification in yeast and humans.15

Citation

Dessen P

TSR3 (TSR3 ribosome maturation factor)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/75257/tsr3