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TSSK3 (testis specific serine kinase 3)

Identity

Alias_namesSTK22C
serine/threonine kinase 22C (spermiogenesis associated)
Alias_symbol (synonym)SPOGA3
Other aliasSTK22D
TSK3
HGNC (Hugo) TSSK3
LocusID (NCBI) 81629
Atlas_Id 75261
Location 1p35.1  [Link to chromosome band 1p35]
Location_base_pair Starts at 32362261 and ends at 32364323 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
ENY2 (8q23.1) / TSSK3 (1p35.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)TSSK3   15473
Cards
Entrez_Gene (NCBI)TSSK3  81629  testis specific serine kinase 3
AliasesSPOGA3; STK22C; STK22D; TSK3
GeneCards (Weizmann)TSSK3
Ensembl hg19 (Hinxton)ENSG00000162526 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000162526 [Gene_View]  chr1:32362261-32364323 [Contig_View]  TSSK3 [Vega]
ICGC DataPortalENSG00000162526
TCGA cBioPortalTSSK3
AceView (NCBI)TSSK3
Genatlas (Paris)TSSK3
WikiGenes81629
SOURCE (Princeton)TSSK3
Genetics Home Reference (NIH)TSSK3
Genomic and cartography
GoldenPath hg38 (UCSC)TSSK3  -     chr1:32362261-32364323 +  1p35.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TSSK3  -     1p35.1   [Description]    (hg19-Feb_2009)
EnsemblTSSK3 - 1p35.1 [CytoView hg19]  TSSK3 - 1p35.1 [CytoView hg38]
Mapping of homologs : NCBITSSK3 [Mapview hg19]  TSSK3 [Mapview hg38]
OMIM607660   
Gene and transcription
Genbank (Entrez)AF296450 AY048701 BC035354 BF509953 DQ891326
RefSeq transcript (Entrez)NM_052841
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)TSSK3
Cluster EST : UnigeneHs.512763 [ NCBI ]
CGAP (NCI)Hs.512763
Alternative Splicing GalleryENSG00000162526
Gene ExpressionTSSK3 [ NCBI-GEO ]   TSSK3 [ EBI - ARRAY_EXPRESS ]   TSSK3 [ SEEK ]   TSSK3 [ MEM ]
Gene Expression Viewer (FireBrowse)TSSK3 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)81629
GTEX Portal (Tissue expression)TSSK3
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96PN8   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ96PN8  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ96PN8
Splice isoforms : SwissVarQ96PN8
Catalytic activity : Enzyme2.7.11.1 [ Enzyme-Expasy ]   2.7.11.12.7.11.1 [ IntEnz-EBI ]   2.7.11.1 [ BRENDA ]   2.7.11.1 [ KEGG ]   
PhosPhoSitePlusQ96PN8
Domaine pattern : Prosite (Expaxy)PROTEIN_KINASE_ATP (PS00107)    PROTEIN_KINASE_DOM (PS50011)   
Domains : Interpro (EBI)Kinase-like_dom    Prot_kinase_dom    Protein_kinase_ATP_BS   
Domain families : Pfam (Sanger)Pkinase (PF00069)   
Domain families : Pfam (NCBI)pfam00069   
Domain families : Smart (EMBL)S_TKc (SM00220)  
Conserved Domain (NCBI)TSSK3
DMDM Disease mutations81629
Blocks (Seattle)TSSK3
SuperfamilyQ96PN8
Human Protein AtlasENSG00000162526
Peptide AtlasQ96PN8
HPRD09635
IPIIPI00044584   
Protein Interaction databases
DIP (DOE-UCLA)Q96PN8
IntAct (EBI)Q96PN8
FunCoupENSG00000162526
BioGRIDTSSK3
STRING (EMBL)TSSK3
ZODIACTSSK3
Ontologies - Pathways
QuickGOQ96PN8
Ontology : AmiGOmagnesium ion binding  protein serine/threonine kinase activity  protein serine/threonine kinase activity  protein binding  ATP binding  nucleus  cytoplasm  protein phosphorylation  protein phosphorylation  multicellular organism development  spermatogenesis  cell differentiation  intracellular signal transduction  
Ontology : EGO-EBImagnesium ion binding  protein serine/threonine kinase activity  protein serine/threonine kinase activity  protein binding  ATP binding  nucleus  cytoplasm  protein phosphorylation  protein phosphorylation  multicellular organism development  spermatogenesis  cell differentiation  intracellular signal transduction  
NDEx NetworkTSSK3
Atlas of Cancer Signalling NetworkTSSK3
Wikipedia pathwaysTSSK3
Orthology - Evolution
OrthoDB81629
GeneTree (enSembl)ENSG00000162526
Phylogenetic Trees/Animal Genes : TreeFamTSSK3
HOVERGENQ96PN8
HOGENOMQ96PN8
Homologs : HomoloGeneTSSK3
Homology/Alignments : Family Browser (UCSC)TSSK3
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTSSK3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TSSK3
dbVarTSSK3
ClinVarTSSK3
1000_GenomesTSSK3 
Exome Variant ServerTSSK3
ExAC (Exome Aggregation Consortium)TSSK3 (select the gene name)
Genetic variants : HAPMAP81629
Genomic Variants (DGV)TSSK3 [DGVbeta]
DECIPHERTSSK3 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTSSK3 
Mutations
ICGC Data PortalTSSK3 
TCGA Data PortalTSSK3 
Broad Tumor PortalTSSK3
OASIS PortalTSSK3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTSSK3  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDTSSK3
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch TSSK3
DgiDB (Drug Gene Interaction Database)TSSK3
DoCM (Curated mutations)TSSK3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)TSSK3 (select a term)
intoGenTSSK3
Cancer3DTSSK3(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM607660   
Orphanet
MedgenTSSK3
Genetic Testing Registry TSSK3
NextProtQ96PN8 [Medical]
TSGene81629
GENETestsTSSK3
Target ValidationTSSK3
Huge Navigator TSSK3 [HugePedia]
snp3D : Map Gene to Disease81629
BioCentury BCIQTSSK3
ClinGenTSSK3
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD81629
Chemical/Pharm GKB GenePA37964
Clinical trialTSSK3
Miscellaneous
canSAR (ICR)TSSK3 (select the gene name)
Probes
Litterature
PubMed10 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTSSK3
EVEXTSSK3
GoPubMedTSSK3
iHOPTSSK3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed May 31 15:47:27 CEST 2017

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