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TSSK4 (testis-specific serine kinase 4)

Identity

Other namesC14orf20
STK22E
TSK-4
TSK4
TSSK5
HGNC (Hugo) TSSK4
LocusID (NCBI) 283629
Atlas_Id 43546
Location 14q12
Location_base_pair Starts at 24674926 and ends at 24677454 bp from pter ( according to hg19-Feb_2009)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)TSSK4   19825
Cards
Entrez_Gene (NCBI)TSSK4  283629  testis-specific serine kinase 4
GeneCards (Weizmann)TSSK4
Ensembl hg19 (Hinxton)ENSG00000139908 [Gene_View]  chr14:24674926-24677454 [Contig_View]  TSSK4 [Vega]
Ensembl hg38 (Hinxton)ENSG00000139908 [Gene_View]  chr14:24674926-24677454 [Contig_View]  TSSK4 [Vega]
ICGC DataPortalENSG00000139908
TCGA cBioPortalTSSK4
AceView (NCBI)TSSK4
Genatlas (Paris)TSSK4
WikiGenes283629
SOURCE (Princeton)TSSK4
Genomic and cartography
GoldenPath hg19 (UCSC)TSSK4  -     chr14:24674926-24677454 +  14q12   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)TSSK4  -     14q12   [Description]    (hg38-Dec_2013)
EnsemblTSSK4 - 14q12 [CytoView hg19]  TSSK4 - 14q12 [CytoView hg38]
Mapping of homologs : NCBITSSK4 [Mapview hg19]  TSSK4 [Mapview hg38]
OMIM610711   
Gene and transcription
Genbank (Entrez)AB528011 AF542390 AK131042 AY461663 BC029918
RefSeq transcript (Entrez)NM_001184739 NM_001308067 NM_174944
RefSeq genomic (Entrez)NC_000014 NC_018925 NT_026437 NW_004929393
Consensus coding sequences : CCDS (NCBI)TSSK4
Cluster EST : UnigeneHs.314432 [ NCBI ]
CGAP (NCI)Hs.314432
Alternative Splicing : Fast-db (Paris)GSHG0008746
Alternative Splicing GalleryENSG00000139908
Gene ExpressionTSSK4 [ NCBI-GEO ]     TSSK4 [ SEEK ]   TSSK4 [ MEM ]
SOURCE (Princeton)Expression in : [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ6SA08 (Uniprot)
NextProtQ6SA08  [Medical]  [Publications]
With graphics : InterProQ6SA08
Splice isoforms : SwissVarQ6SA08 (Swissvar)
Catalytic activity : Enzyme2.7.11.1 [ Enzyme-Expasy ]   2.7.11.12.7.11.1 [ IntEnz-EBI ]   2.7.11.1 [ BRENDA ]   2.7.11.1 [ KEGG ]   
Domaine pattern : Prosite (Expaxy)PROTEIN_KINASE_ATP (PS00107)    PROTEIN_KINASE_DOM (PS50011)    PROTEIN_KINASE_ST (PS00108)   
Domains : Interpro (EBI)Integrin-linked_kinase    Kinase-like_dom    Prot_kinase_dom    Protein_kinase_ATP_BS    Ser/Thr_dual-sp_kinase    Ser/Thr_kinase_AS   
Related proteins : CluSTrQ6SA08
Domain families : Pfam (Sanger)Pkinase (PF00069)   
Domain families : Pfam (NCBI)pfam00069   
Domain families : Smart (EMBL)S_TKc (SM00220)  
DMDM Disease mutations283629
Blocks (Seattle)Q6SA08
Human Protein AtlasENSG00000139908
Peptide AtlasQ6SA08
HPRD12642
IPIIPI00646936   IPI00414440   IPI00829727   IPI00748455   IPI00795515   IPI01025944   IPI01026038   
Protein Interaction databases
DIP (DOE-UCLA)Q6SA08
IntAct (EBI)Q6SA08
FunCoupENSG00000139908
BioGRIDTSSK4
IntegromeDBTSSK4
STRING (EMBL)TSSK4
Ontologies - Pathways
QuickGOQ6SA08
Ontology : AmiGOmagnesium ion binding  magnesium ion binding  protein serine/threonine kinase activity  protein serine/threonine kinase activity  protein binding  ATP binding  ATP binding  cytoplasm  protein phosphorylation  protein phosphorylation  multicellular organismal development  spermatogenesis  regulation of signal transduction  cell differentiation  positive regulation of CREB transcription factor activity  intracellular signal transduction  
Ontology : EGO-EBImagnesium ion binding  magnesium ion binding  protein serine/threonine kinase activity  protein serine/threonine kinase activity  protein binding  ATP binding  ATP binding  cytoplasm  protein phosphorylation  protein phosphorylation  multicellular organismal development  spermatogenesis  regulation of signal transduction  cell differentiation  positive regulation of CREB transcription factor activity  intracellular signal transduction  
Protein Interaction DatabaseTSSK4
DoCM (Curated mutations)TSSK4
Wikipedia pathwaysTSSK4
Gene fusion - Rearrangements
Gene fusion: TCGA
Polymorphisms : SNP, variants
NCBI Variation ViewerTSSK4 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TSSK4
dbVarTSSK4
ClinVarTSSK4
1000_GenomesTSSK4 
Exome Variant ServerTSSK4
SNP (GeneSNP Utah)TSSK4
SNP : HGBaseTSSK4
Genetic variants : HAPMAPTSSK4
Genomic Variants (DGV)TSSK4 [DGVbeta]
Mutations
ICGC Data PortalTSSK4 
TCGA Data PortalTSSK4 
Tumor PortalTSSK4
Somatic Mutations in Cancer : COSMICTSSK4 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] 
Diseases
DECIPHER (Syndromes)14:24674926-24677454
CONAN: Copy Number AnalysisTSSK4 
Mutations and Diseases : HGMDTSSK4
OMIM610711   
MedgenTSSK4
NextProtQ6SA08 [Medical]
GENETestsTSSK4
Disease Genetic AssociationTSSK4
Huge Navigator TSSK4 [HugePedia]  TSSK4 [HugeCancerGEM]
snp3D : Map Gene to Disease283629
DGIdb (Drug Gene Interaction db)TSSK4
BioCentury BCIQTSSK4
General knowledge
Homologs : HomoloGeneTSSK4
Homology/Alignments : Family Browser (UCSC)TSSK4
Phylogenetic Trees/Animal Genes : TreeFamTSSK4
Chemical/Protein Interactions : CTD283629
Chemical/Pharm GKB GenePA134908318
Clinical trialTSSK4
Cancer Resource (Charite)ENSG00000139908
Other databases
Probes
Litterature
PubMed9 Pubmed reference(s) in Entrez
CoreMineTSSK4
GoPubMedTSSK4
iHOPTSSK4
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated02-2015Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Sat Jun 27 12:27:40 CEST 2015

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