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TSSK4 (testis-specific serine kinase 4)

Identity

Other namesC14orf20
STK22E
TSK-4
TSK4
TSSK5
HGNC (Hugo) TSSK4
LocusID (NCBI) 283629
Location 14q12
Location_base_pair Starts at 24674926 and ends at 24677454 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)TSSK4   19825
Cards
Entrez_Gene (NCBI)TSSK4  283629  testis-specific serine kinase 4
GeneCards (Weizmann)TSSK4
Ensembl (Hinxton)ENSG00000139908 [Gene_View]  chr14:24674926-24677454 [Contig_View]  TSSK4 [Vega]
ICGC DataPortalENSG00000139908
cBioPortalTSSK4
AceView (NCBI)TSSK4
Genatlas (Paris)TSSK4
WikiGenes283629
SOURCE (Princeton)NM_001184739 NM_174944
Genomic and cartography
GoldenPath (UCSC)TSSK4  -  14q12   chr14:24674926-24677454 +  14q12   [Description]    (hg19-Feb_2009)
EnsemblTSSK4 - 14q12 [CytoView]
Mapping of homologs : NCBITSSK4 [Mapview]
OMIM610711   
Gene and transcription
Genbank (Entrez)AB528011 AF542390 AK131042 AY461663 BC029918
RefSeq transcript (Entrez)NM_001184739 NM_174944
RefSeq genomic (Entrez)AC_000146 NC_000014 NC_018925 NT_026437 NW_001838110 NW_004929393
Consensus coding sequences : CCDS (NCBI)TSSK4
Cluster EST : UnigeneHs.314432 [ NCBI ]
CGAP (NCI)Hs.314432
Alternative Splicing : Fast-db (Paris)GSHG0008746
Alternative Splicing GalleryENSG00000139908
Gene ExpressionTSSK4 [ NCBI-GEO ]     TSSK4 [ SEEK ]   TSSK4 [ MEM ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ6SA08 (Uniprot)
NextProtQ6SA08  [Medical]
With graphics : InterProQ6SA08
Splice isoforms : SwissVarQ6SA08 (Swissvar)
Catalytic activity : Enzyme2.7.11.1 [ Enzyme-Expasy ]   2.7.11.12.7.11.1 [ IntEnz-EBI ]   2.7.11.1 [ BRENDA ]   2.7.11.1 [ KEGG ]   
Domaine pattern : Prosite (Expaxy)PROTEIN_KINASE_ATP (PS00107)    PROTEIN_KINASE_DOM (PS50011)    PROTEIN_KINASE_ST (PS00108)   
Domains : Interpro (EBI)Kinase-like_dom [organisation]   Prot_kinase_dom [organisation]   Protein_kinase_ATP_BS [organisation]   Ser/Thr_dual-sp_kinase_dom [organisation]   Ser/Thr_kinase_AS [organisation]  
Related proteins : CluSTrQ6SA08
Domain families : Pfam (Sanger)Pkinase (PF00069)   
Domain families : Pfam (NCBI)pfam00069   
Domain families : Smart (EMBL)S_TKc (SM00220)  
DMDM Disease mutations283629
Blocks (Seattle)Q6SA08
Human Protein AtlasENSG00000139908 [gene] [tissue] [antibody] [cell] [cancer]
Peptide AtlasQ6SA08
HPRD12642
IPIIPI00646936   IPI00414440   IPI00829727   IPI00748455   IPI00795515   IPI01025944   IPI01026038   
Protein Interaction databases
DIP (DOE-UCLA)Q6SA08
IntAct (EBI)Q6SA08
FunCoupENSG00000139908
BioGRIDTSSK4
InParanoidQ6SA08
Interologous Interaction database Q6SA08
IntegromeDBTSSK4
STRING (EMBL)TSSK4
Ontologies - Pathways
Ontology : AmiGOmagnesium ion binding  magnesium ion binding  protein serine/threonine kinase activity  protein serine/threonine kinase activity  protein binding  ATP binding  ATP binding  protein phosphorylation  protein phosphorylation  multicellular organismal development  spermatogenesis  cell differentiation  positive regulation of CREB transcription factor activity  
Ontology : EGO-EBImagnesium ion binding  magnesium ion binding  protein serine/threonine kinase activity  protein serine/threonine kinase activity  protein binding  ATP binding  ATP binding  protein phosphorylation  protein phosphorylation  multicellular organismal development  spermatogenesis  cell differentiation  positive regulation of CREB transcription factor activity  
Protein Interaction DatabaseTSSK4
Wikipedia pathwaysTSSK4
Gene fusion - rearrangments
Polymorphisms : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)TSSK4
snp3D : Map Gene to Disease283629
SNP (GeneSNP Utah)TSSK4
SNP : HGBaseTSSK4
Genetic variants : HAPMAPTSSK4
Exome VariantTSSK4
1000_GenomesTSSK4 
ICGC programENSG00000139908 
Somatic Mutations in Cancer : COSMICTSSK4 
CONAN: Copy Number AnalysisTSSK4 
Mutations and Diseases : HGMDTSSK4
Genomic VariantsTSSK4  TSSK4 [DGVbeta]
dbVarTSSK4
ClinVarTSSK4
Pred. of missensesPolyPhen-2  SIFT(SG)  SIFT(JCVI)  Align-GVGD  MutAssessor  Mutanalyser  
Pred. splicesGeneSplicer  Human Splicing Finder  MaxEntScan  
Diseases
OMIM610711   
MedgenTSSK4
GENETestsTSSK4
Disease Genetic AssociationTSSK4
Huge Navigator TSSK4 [HugePedia]  TSSK4 [HugeCancerGEM]
General knowledge
Homologs : HomoloGeneTSSK4
Homology/Alignments : Family Browser (UCSC)TSSK4
Phylogenetic Trees/Animal Genes : TreeFamTSSK4
Chemical/Protein Interactions : CTD283629
Chemical/Pharm GKB GenePA134908318
Clinical trialTSSK4
Cancer Resource (Charite)ENSG00000139908
Other databases
Probes
Litterature
PubMed9 Pubmed reference(s) in Entrez
CoreMineTSSK4
iHOPTSSK4
OncoSearchTSSK4
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated12-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed Jul 30 14:20:14 CEST 2014

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