TTBK2 (tau tubulin kinase 2)

Identity

Other names	KIAA0847
	SCA11
	TTBK
HGNC	TTBK2
Location	15q15.2
Note	Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

External links

	Nomenclature
HGNC	TTBK2   19141
Entrez_Gene	TTBK2  146057  tau tubulin kinase 2
	Cards
GeneCards	TTBK2
Ensembl	TTBK2 [Search_View]   ENSG00000128881 [Gene_View]
Genatlas	TTBK2
GeneLynx	TTBK2
eGenome	TTBK2
euGene	146057
	Genomic and cartography
GoldenPath	TTBK2  -  15q15.2   chr15:40823836-41000299 -  15q15.2   [Description]    (hg18-March_2006)
Ensembl	TTBK2 - 15q15.2 [CytoView]
NCBI	Mapview
OMIM	Disease map [OMIM]
HomoloGene	TTBK2
	Gene and transcription
Genbank	AB020654 [ ENTREZ ]
Genbank	AF525400 [ ENTREZ ]
Genbank	AK131372 [ ENTREZ ]
Genbank	BC041876 [ ENTREZ ]
Genbank	BC071556 [ ENTREZ ]
RefSeq	NM_173500 [ SRS ]    NM_173500 [ ENTREZ ]
RefSeq	AC_000058 [ SRS ]    AC_000058 [ ENTREZ ]
RefSeq	AC_000147 [ SRS ]    AC_000147 [ ENTREZ ]
RefSeq	NC_000015 [ SRS ]    NC_000015 [ ENTREZ ]
RefSeq	NT_010194 [ SRS ]    NT_010194 [ ENTREZ ]
RefSeq	NW_001838214 [ SRS ]    NW_001838214 [ ENTREZ ]
RefSeq	NW_925840 [ SRS ]    NW_925840 [ ENTREZ ]
AceView	TTBK2 AceView - NCBI
Unigene	Hs.713940 [ SRS ]    Hs.713940 [ NCBI ]     HS713940 [ spliceNest ]
Fast-db	3292 (alternative variants)
	Protein : pattern, domain, 3D structure
SwissProt	Q6IQ55 [ SRS]    Q6IQ55 [ EXPASY ]     Q6IQ55 [ INTERPRO ]     Q6IQ55 [ UNIPROT ]
Prosite	PS00107 PROTEIN_KINASE_ATP [ SRS ]    PS00107 PROTEIN_KINASE_ATP [ Expasy ]
Prosite	PS50011 PROTEIN_KINASE_DOM [ SRS ]    PS50011 PROTEIN_KINASE_DOM [ Expasy ]
Prosite	PS00108 PROTEIN_KINASE_ST [ SRS ]    PS00108 PROTEIN_KINASE_ST [ Expasy ]
Interpro	IPR000719 Prot_kinase_core [ SRS ]    IPR000719 Prot_kinase_core [ EBI ]
Interpro	IPR017441 Protein_kinase_ATP_bd_CS [ SRS ]    IPR017441 Protein_kinase_ATP_bd_CS [ EBI ]
Interpro	IPR017442 Se/Thr_pkinase-rel [ SRS ]    IPR017442 Se/Thr_pkinase-rel [ EBI ]
Interpro	IPR008271 Ser_thr_pkin_AS [ SRS ]    IPR008271 Ser_thr_pkin_AS [ EBI ]
CluSTr	Q6IQ55
Pfam	PF00069 Pkinase [ SRS ]    PF00069 Pkinase [ Sanger ]    pfam00069 [ NCBI-CDD ]
Prodom	PD000001 Prot_kinase[INRA-Toulouse]
Prodom	Q6IQ55 TTBK2_HUMAN [ Domain structure ]   Q6IQ55 TTBK2_HUMAN  [ sequences sharing at least 1 domain ]
Blocks	Q6IQ55
HPRD	10288
	Protein Interaction databases
DIP	Q6IQ55
IntAct	Q6IQ55
	Polymorphism : SNP, mutations, diseases
OMIM	604432;611695    [ map ]
GENECLINICS	604432;611695
SNP	TTBK2 [dbSNP-NCBI]
SNP	NM_173500 [SNP-NCI]
SNP	TTBK2 [GeneSNPs - Utah]  TTBK2] [HGBASE - SRS]
HAPMAP	TTBK2 [HAPMAP]
COSMIC	TTBK2 [Somatic mutation (COSMIC-CGP-Sanger)]
HGMD	TTBK2
	General knowledge
Family Browser	TTBK2 [UCSC Family Browser]
SOURCE	NM_173500
SMD	Hs.713940
SAGE	Hs.713940
GO	nucleotide binding [Amigo]  nucleotide binding
GO	protein kinase activity [Amigo]  protein kinase activity
GO	protein serine/threonine kinase activity [Amigo]  protein serine/threonine kinase activity
GO	structural molecule activity [Amigo]  structural molecule activity
GO	ATP binding [Amigo]  ATP binding
GO	intermediate filament [Amigo]  intermediate filament
GO	protein amino acid phosphorylation [Amigo]  protein amino acid phosphorylation
GO	cell death [Amigo]  cell death
GO	transferase activity [Amigo]  transferase activity
PubGene	TTBK2
TreeFam	TTBK2
CTD	146057 [Comparative ToxicoGenomics Database]
	Other databases
	Probes
Probe	TTBK2 Related clones (RZPD - Berlin)
	PubMed
PubMed	10 Pubmed reference(s) in LocusLink

Genes in title	automatic search in PubMed
REVIEW articles	automatic search in PubMed
Last year publications	automatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written	09-2002	Dessen P, Le Minor S
Updated	03-2008	Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Mon Aug 11 20:36:48 2008