Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 146057
MIM: 611695
HGNC: 19141
Ensembl: ENSG00000128881
Variants:
dbSNP: 146057
ClinVar: 146057
TCGA: ENSG00000128881
COSMIC: TTBK2
RNA/Proteins
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Organelle biogenesis and maintenance | REACTOME | R-HSA-1852241 |
| Cilium Assembly | REACTOME | R-HSA-5617833 |
| Anchoring of the basal body to the plasma membrane | REACTOME | R-HSA-5620912 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36892783 | 2024 | Spinocerebellar ataxia type 11 (SCA11): TTBK2 variants, functions and associated disease mechanisms. | 0 |
| 37848700 | 2024 | A Novel TTBK2 Mutation in a Chinese Pedigree with Spinocerebellar Ataxia 11. | 0 |
| 36892783 | 2024 | Spinocerebellar ataxia type 11 (SCA11): TTBK2 variants, functions and associated disease mechanisms. | 0 |
| 37848700 | 2024 | A Novel TTBK2 Mutation in a Chinese Pedigree with Spinocerebellar Ataxia 11. | 0 |
| 37059819 | 2023 | Modulation of tau tubulin kinases (TTBK1 and TTBK2) impacts ciliogenesis. | 4 |
| 37059819 | 2023 | Modulation of tau tubulin kinases (TTBK1 and TTBK2) impacts ciliogenesis. | 4 |
| 34499853 | 2022 | Molecular mechanisms underlying the role of the centriolar CEP164-TTBK2 complex in ciliopathies. | 6 |
| 34499853 | 2022 | Molecular mechanisms underlying the role of the centriolar CEP164-TTBK2 complex in ciliopathies. | 6 |
| 33846249 | 2021 | A complex of distal appendage-associated kinases linked to human disease regulates ciliary trafficking and stability. | 10 |
| 33846249 | 2021 | A complex of distal appendage-associated kinases linked to human disease regulates ciliary trafficking and stability. | 10 |
| 32129703 | 2020 | Phosphorylation of multiple proteins involved in ciliogenesis by Tau Tubulin kinase 2. | 19 |
| 32196629 | 2020 | Circular RNA TTBK2 regulates cell proliferation, invasion and ferroptosis via miR-761/ITGB8 axis in glioma. | 53 |
| 32129703 | 2020 | Phosphorylation of multiple proteins involved in ciliogenesis by Tau Tubulin kinase 2. | 19 |
| 32196629 | 2020 | Circular RNA TTBK2 regulates cell proliferation, invasion and ferroptosis via miR-761/ITGB8 axis in glioma. | 53 |
| 31455668 | 2019 | Phosphorylation of CEP83 by TTBK2 is necessary for cilia initiation. | 34 |
Citation
Dessen P
TTBK2 (tau tubulin kinase 2)
Atlas Genet Cytogenet Oncol Haematol. 2006-10-01
Online version: http://atlasgeneticsoncology.org/gene/43548/ttbk2
