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TTC1 (tetratricopeptide repeat domain 1)

Identity

Alias_symbol (synonym)TPR1
Other alias
HGNC (Hugo) TTC1
LocusID (NCBI) 7265
Atlas_Id 75267
Location 5q33.3  [Link to chromosome band 5q33]
Location_base_pair Starts at 160009100 and ends at 160065545 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
TTC1 (5q33.3) / CDC42EP3 (2p22.2)TTC1 (5q33.3) / IL32 (16p13.3)TTC1 (5q33.3) / TTC1 (5q33.3)
TTC1 (5q33.3) / ZCCHC17 (1p35.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)TTC1   12391
Cards
Entrez_Gene (NCBI)TTC1  7265  tetratricopeptide repeat domain 1
AliasesTPR1
GeneCards (Weizmann)TTC1
Ensembl hg19 (Hinxton)ENSG00000113312 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000113312 [Gene_View]  chr5:160009100-160065545 [Contig_View]  TTC1 [Vega]
ICGC DataPortalENSG00000113312
TCGA cBioPortalTTC1
AceView (NCBI)TTC1
Genatlas (Paris)TTC1
WikiGenes7265
SOURCE (Princeton)TTC1
Genetics Home Reference (NIH)TTC1
Genomic and cartography
GoldenPath hg38 (UCSC)TTC1  -     chr5:160009100-160065545 +  5q33.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TTC1  -     5q33.3   [Description]    (hg19-Feb_2009)
EnsemblTTC1 - 5q33.3 [CytoView hg19]  TTC1 - 5q33.3 [CytoView hg38]
Mapping of homologs : NCBITTC1 [Mapview hg19]  TTC1 [Mapview hg38]
OMIM601963   
Gene and transcription
Genbank (Entrez)AK128840 AK222641 AK222984 AK315262 BC000942
RefSeq transcript (Entrez)NM_001282500 NM_003314
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)TTC1
Cluster EST : UnigeneHs.519718 [ NCBI ]
CGAP (NCI)Hs.519718
Alternative Splicing GalleryENSG00000113312
Gene ExpressionTTC1 [ NCBI-GEO ]   TTC1 [ EBI - ARRAY_EXPRESS ]   TTC1 [ SEEK ]   TTC1 [ MEM ]
Gene Expression Viewer (FireBrowse)TTC1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)7265
GTEX Portal (Tissue expression)TTC1
Human Protein AtlasENSG00000113312-TTC1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ99614   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ99614  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ99614
Splice isoforms : SwissVarQ99614
PhosPhoSitePlusQ99614
Domaine pattern : Prosite (Expaxy)TPR (PS50005)    TPR_REGION (PS50293)   
Domains : Interpro (EBI)TPR-contain_dom    TPR-like_helical_dom    TPR_1    TPR_repeat   
Domain families : Pfam (Sanger)TPR_1 (PF00515)    TPR_8 (PF13181)   
Domain families : Pfam (NCBI)pfam00515    pfam13181   
Domain families : Smart (EMBL)TPR (SM00028)  
Conserved Domain (NCBI)TTC1
DMDM Disease mutations7265
Blocks (Seattle)TTC1
SuperfamilyQ99614
Human Protein Atlas [tissue]ENSG00000113312-TTC1 [tissue]
Peptide AtlasQ99614
HPRD11881
IPIIPI00016912   IPI00976539   
Protein Interaction databases
DIP (DOE-UCLA)Q99614
IntAct (EBI)Q99614
FunCoupENSG00000113312
BioGRIDTTC1
STRING (EMBL)TTC1
ZODIACTTC1
Ontologies - Pathways
QuickGOQ99614
Ontology : AmiGOprotein binding  peroxisomal membrane  cytosol  protein folding  unfolded protein binding  
Ontology : EGO-EBIprotein binding  peroxisomal membrane  cytosol  protein folding  unfolded protein binding  
NDEx NetworkTTC1
Atlas of Cancer Signalling NetworkTTC1
Wikipedia pathwaysTTC1
Orthology - Evolution
OrthoDB7265
GeneTree (enSembl)ENSG00000113312
Phylogenetic Trees/Animal Genes : TreeFamTTC1
HOVERGENQ99614
HOGENOMQ99614
Homologs : HomoloGeneTTC1
Homology/Alignments : Family Browser (UCSC)TTC1
Gene fusions - Rearrangements
Fusion: Tumor Portal TTC1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTTC1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TTC1
dbVarTTC1
ClinVarTTC1
1000_GenomesTTC1 
Exome Variant ServerTTC1
ExAC (Exome Aggregation Consortium)ENSG00000113312
GNOMAD BrowserENSG00000113312
Genetic variants : HAPMAP7265
Genomic Variants (DGV)TTC1 [DGVbeta]
DECIPHERTTC1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTTC1 
Mutations
ICGC Data PortalTTC1 
TCGA Data PortalTTC1 
Broad Tumor PortalTTC1
OASIS PortalTTC1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTTC1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDTTC1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch TTC1
DgiDB (Drug Gene Interaction Database)TTC1
DoCM (Curated mutations)TTC1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)TTC1 (select a term)
intoGenTTC1
Cancer3DTTC1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM601963   
Orphanet
MedgenTTC1
Genetic Testing Registry TTC1
NextProtQ99614 [Medical]
TSGene7265
GENETestsTTC1
Target ValidationTTC1
Huge Navigator TTC1 [HugePedia]
snp3D : Map Gene to Disease7265
BioCentury BCIQTTC1
ClinGenTTC1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD7265
Chemical/Pharm GKB GenePA37057
Clinical trialTTC1
Miscellaneous
canSAR (ICR)TTC1 (select the gene name)
Probes
Litterature
PubMed32 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTTC1
EVEXTTC1
GoPubMedTTC1
iHOPTTC1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Nov 9 12:34:20 CET 2017

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