Atlas of Genetics and Cytogenetics in Oncology and Haematology

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TTC17 (tetratricopeptide repeat domain 17)

Identity

Alias_symbol (synonym)FLJ10890
Other alias-
HGNC (Hugo) TTC17
LocusID (NCBI) 55761
Atlas_Id 54731
Location 11p12  [Link to chromosome band 11p12]
Location_base_pair Starts at 43358885 and ends at 43494933 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
BIRC2 (11q22.2) / TTC17 (11p12)BMPR2 (2q33.1) / TTC17 (11p12)TTC17 (11p12) / TNFRSF1A (12p13.31)
TTC17 (11p12) / TTC28 (22q12.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 1 ]
  t(11;22)(p12;q12) TTC17/TTC28

External links

Nomenclature
HGNC (Hugo)TTC17   25596
Cards
Entrez_Gene (NCBI)TTC17  55761  tetratricopeptide repeat domain 17
Aliases
GeneCards (Weizmann)TTC17
Ensembl hg19 (Hinxton)ENSG00000052841 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000052841 [Gene_View]  chr11:43358885-43494933 [Contig_View]  TTC17 [Vega]
ICGC DataPortalENSG00000052841
TCGA cBioPortalTTC17
AceView (NCBI)TTC17
Genatlas (Paris)TTC17
WikiGenes55761
SOURCE (Princeton)TTC17
Genetics Home Reference (NIH)TTC17
Genomic and cartography
GoldenPath hg38 (UCSC)TTC17  -     chr11:43358885-43494933 +  11p12   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TTC17  -     11p12   [Description]    (hg19-Feb_2009)
EnsemblTTC17 - 11p12 [CytoView hg19]  TTC17 - 11p12 [CytoView hg38]
Mapping of homologs : NCBITTC17 [Mapview hg19]  TTC17 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AF161431 AK001540 AK001752 AK023161 AK026217
RefSeq transcript (Entrez)NM_001307943 NM_018259
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)TTC17
Cluster EST : UnigeneHs.191186 [ NCBI ]
CGAP (NCI)Hs.191186
Alternative Splicing GalleryENSG00000052841
Gene ExpressionTTC17 [ NCBI-GEO ]   TTC17 [ EBI - ARRAY_EXPRESS ]   TTC17 [ SEEK ]   TTC17 [ MEM ]
Gene Expression Viewer (FireBrowse)TTC17 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)55761
GTEX Portal (Tissue expression)TTC17
Human Protein AtlasENSG00000052841-TTC17 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96AE7   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ96AE7  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ96AE7
Splice isoforms : SwissVarQ96AE7
PhosPhoSitePlusQ96AE7
Domaine pattern : Prosite (Expaxy)TPR (PS50005)    TPR_REGION (PS50293)   
Domains : Interpro (EBI)TPR-contain_dom    TPR-like_helical_dom    TPR_repeat   
Domain families : Pfam (Sanger)TPR_8 (PF13181)   
Domain families : Pfam (NCBI)pfam13181   
Domain families : Smart (EMBL)TPR (SM00028)  
Conserved Domain (NCBI)TTC17
DMDM Disease mutations55761
Blocks (Seattle)TTC17
SuperfamilyQ96AE7
Human Protein Atlas [tissue]ENSG00000052841-TTC17 [tissue]
Peptide AtlasQ96AE7
HPRD15582
IPIIPI00302966   IPI00640719   IPI00981133   IPI00974468   IPI00302309   
Protein Interaction databases
DIP (DOE-UCLA)Q96AE7
IntAct (EBI)Q96AE7
FunCoupENSG00000052841
BioGRIDTTC17
STRING (EMBL)TTC17
ZODIACTTC17
Ontologies - Pathways
QuickGOQ96AE7
Ontology : AmiGOprotein binding  cytoplasm  cytosol  plasma membrane  actin cytoskeleton  actin filament polymerization  cilium organization  
Ontology : EGO-EBIprotein binding  cytoplasm  cytosol  plasma membrane  actin cytoskeleton  actin filament polymerization  cilium organization  
NDEx NetworkTTC17
Atlas of Cancer Signalling NetworkTTC17
Wikipedia pathwaysTTC17
Orthology - Evolution
OrthoDB55761
GeneTree (enSembl)ENSG00000052841
Phylogenetic Trees/Animal Genes : TreeFamTTC17
HOVERGENQ96AE7
HOGENOMQ96AE7
Homologs : HomoloGeneTTC17
Homology/Alignments : Family Browser (UCSC)TTC17
Gene fusions - Rearrangements
Fusion : MitelmanTTC17/TTC28 [11p12/22q12.1]  
Fusion : QuiverTTC17
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTTC17 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TTC17
dbVarTTC17
ClinVarTTC17
1000_GenomesTTC17 
Exome Variant ServerTTC17
ExAC (Exome Aggregation Consortium)ENSG00000052841
GNOMAD BrowserENSG00000052841
Genetic variants : HAPMAP55761
Genomic Variants (DGV)TTC17 [DGVbeta]
DECIPHERTTC17 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTTC17 
Mutations
ICGC Data PortalTTC17 
TCGA Data PortalTTC17 
Broad Tumor PortalTTC17
OASIS PortalTTC17 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTTC17  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDTTC17
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch TTC17
DgiDB (Drug Gene Interaction Database)TTC17
DoCM (Curated mutations)TTC17 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)TTC17 (select a term)
intoGenTTC17
Cancer3DTTC17(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
DisGeNETTTC17
MedgenTTC17
Genetic Testing Registry TTC17
NextProtQ96AE7 [Medical]
TSGene55761
GENETestsTTC17
Target ValidationTTC17
Huge Navigator TTC17 [HugePedia]
snp3D : Map Gene to Disease55761
BioCentury BCIQTTC17
ClinGenTTC17
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD55761
Chemical/Pharm GKB GenePA134912435
Clinical trialTTC17
Miscellaneous
canSAR (ICR)TTC17 (select the gene name)
Probes
Litterature
PubMed13 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTTC17
EVEXTTC17
GoPubMedTTC17
iHOPTTC17
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Feb 28 13:43:27 CET 2018
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