TTC21A (tetratricopeptide repeat domain 21A)

2014-11-01  

Identity

HGNC
TTC21A
LOCATION
3p22.2
LOCUSID
199223
ALIAS
IFT139A,SPGF37,STI2
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 199223
MIM: 611430
HGNC: 30761
Ensembl: ENSG00000168026

Variants:

dbSNP: 199223
ClinVar: 199223
TCGA: ENSG00000168026
COSMIC: TTC21A

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000168026ENST00000425163F8WDN4
ENSG00000168026ENST00000430597A0A0B4J1Y2
ENSG00000168026ENST00000431162Q8NDW8
ENSG00000168026ENST00000431559A0A0C4DH51
ENSG00000168026ENST00000440121Q8NDW8

Expression (GTEx)

0
10
20
30
40
50
60
70
80
90
100
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
309297352019Bi-allelic Mutations in TTC21A Induce Asthenoteratospermia in Humans and Mice.11

Citation

Dessen P

TTC21A (tetratricopeptide repeat domain 21A)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/75271/ttc21a