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TTC33 (tetratricopeptide repeat domain 33)

Identity

Alias (NCBI)OSRF
HGNC (Hugo) TTC33
HGNC Alias symbOSRF
HGNC Alias nameosmosis responsive factor
LocusID (NCBI) 23548
Atlas_Id 75287
Location 5p13.1  [Link to chromosome band 5p13]
Location_base_pair Starts at 40711576 and ends at 40755961 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
PRKAA1 (5p13.1) / TTC33 (5p13.1)TTC33 (5p13.1) / AC008810.1 ()TTC33 (5p13.1) / ADAM19 (5q33.3)
TTC33 (5p13.1) / GRM5 (11q14.2)TTC33 AC008810.1TTC33 ADAM19
TTC33 GRM5

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



Other Leukemias implicated (Data extracted from papers in the Atlas) [ 2 ]
  t(5;5)(p13;p13) PRKAA1/TTC33
t(5;5)(p13;p13) PRKAA1/TTC33


External links

 

Nomenclature
HGNC (Hugo)TTC33   29959
Cards
Entrez_Gene (NCBI)TTC33    tetratricopeptide repeat domain 33
AliasesOSRF
GeneCards (Weizmann)TTC33
Ensembl hg19 (Hinxton)ENSG00000113638 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000113638 [Gene_View]  ENSG00000113638 [Sequence]  chr5:40711576-40755961 [Contig_View]  TTC33 [Vega]
ICGC DataPortalENSG00000113638
TCGA cBioPortalTTC33
AceView (NCBI)TTC33
Genatlas (Paris)TTC33
SOURCE (Princeton)TTC33
Genetics Home Reference (NIH)TTC33
Genomic and cartography
GoldenPath hg38 (UCSC)TTC33  -     chr5:40711576-40755961 -  5p13.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TTC33  -     5p13.1   [Description]    (hg19-Feb_2009)
GoldenPathTTC33 - 5p13.1 [CytoView hg19]  TTC33 - 5p13.1 [CytoView hg38]
ImmunoBaseENSG00000113638
Genome Data Viewer NCBITTC33 [Mapview hg19]  
Gene and transcription
Genbank (Entrez)AF023244 AF130073 AI174764 AK303119 AK307131
RefSeq transcript (Entrez)NM_012382
Consensus coding sequences : CCDS (NCBI)TTC33
Gene ExpressionTTC33 [ NCBI-GEO ]   TTC33 [ EBI - ARRAY_EXPRESS ]   TTC33 [ SEEK ]   TTC33 [ MEM ]
Gene Expression Viewer (FireBrowse)TTC33 [ Firebrowse - Broad ]
GenevisibleExpression of TTC33 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)23548
GTEX Portal (Tissue expression)TTC33
Human Protein AtlasENSG00000113638-TTC33 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ6PID6   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ6PID6  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ6PID6
PhosPhoSitePlusQ6PID6
Domaine pattern : Prosite (Expaxy)TPR (PS50005)    TPR_REGION (PS50293)   
Domains : Interpro (EBI)TPR-contain_dom    TPR-like_helical_dom_sf    TPR_repeat   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Domain families : Smart (EMBL)TPR (SM00028)  
Conserved Domain (NCBI)TTC33
SuperfamilyQ6PID6
AlphaFold pdb e-kbQ6PID6   
Human Protein Atlas [tissue]ENSG00000113638-TTC33 [tissue]
HPRD17807
Protein Interaction databases
DIP (DOE-UCLA)Q6PID6
IntAct (EBI)Q6PID6
BioGRIDTTC33
STRING (EMBL)TTC33
ZODIACTTC33
Ontologies - Pathways
QuickGOQ6PID6
Ontology : AmiGOprotein binding  
Ontology : EGO-EBIprotein binding  
NDEx NetworkTTC33
Atlas of Cancer Signalling NetworkTTC33
Wikipedia pathwaysTTC33
Orthology - Evolution
OrthoDB23548
GeneTree (enSembl)ENSG00000113638
Phylogenetic Trees/Animal Genes : TreeFamTTC33
Homologs : HomoloGeneTTC33
Homology/Alignments : Family Browser (UCSC)TTC33
Gene fusions - Rearrangements
Fusion : QuiverTTC33
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTTC33 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TTC33
dbVarTTC33
ClinVarTTC33
MonarchTTC33
1000_GenomesTTC33 
Exome Variant ServerTTC33
GNOMAD BrowserENSG00000113638
Varsome BrowserTTC33
ACMGTTC33 variants
VarityQ6PID6
Genomic Variants (DGV)TTC33 [DGVbeta]
DECIPHERTTC33 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTTC33 
Mutations
ICGC Data PortalTTC33 
TCGA Data PortalTTC33 
Broad Tumor PortalTTC33
OASIS PortalTTC33 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTTC33  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DTTC33
Mutations and Diseases : HGMDTTC33
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaTTC33
DgiDB (Drug Gene Interaction Database)TTC33
DoCM (Curated mutations)TTC33
CIViC (Clinical Interpretations of Variants in Cancer)TTC33
Cancer3DTTC33
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
DisGeNETTTC33
MedgenTTC33
Genetic Testing Registry TTC33
NextProtQ6PID6 [Medical]
GENETestsTTC33
Target ValidationTTC33
Huge Navigator TTC33 [HugePedia]
ClinGenTTC33
Clinical trials, drugs, therapy
MyCancerGenomeTTC33
Protein Interactions : CTDTTC33
Pharm GKB GenePA162407196
PharosQ6PID6
Clinical trialTTC33
Miscellaneous
canSAR (ICR)TTC33
HarmonizomeTTC33
DataMed IndexTTC33
Probes
Litterature
PubMed16 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXTTC33
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Mon Oct 4 16:27:18 CEST 2021

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