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TTC37 (tetratricopeptide repeat domain 37)

Identity

Alias_namesKIAA0372
KIAA0372
Alias_symbol (synonym)THES
Other aliasSki3
HGNC (Hugo) TTC37
LocusID (NCBI) 9652
Atlas_Id 75289
Location 5q15  [Link to chromosome band 5q15]
Location_base_pair Starts at 95463895 and ends at 95555005 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
NOS2 (17q11.2) / TTC37 (5q15)NQO1 (16q22.1) / TTC37 (5q15)NUDT10 (Xp11.22) / TTC37 (5q15)
RNPC3 (1p21.1) / TTC37 (5q15)SLC36A1 (5q33.1) / TTC37 (5q15)TTC37 (5q15) / MFSD4A (1q32.1)
TTC37 (5q15) / RBPMS (8p12)TTC37 (5q15) / RPL30 (8q22.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)TTC37   23639
LRG (Locus Reference Genomic)LRG_173
Cards
Entrez_Gene (NCBI)TTC37  9652  tetratricopeptide repeat domain 37
AliasesKIAA0372; Ski3; THES
GeneCards (Weizmann)TTC37
Ensembl hg19 (Hinxton)ENSG00000198677 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000198677 [Gene_View]  chr5:95463895-95555005 [Contig_View]  TTC37 [Vega]
ICGC DataPortalENSG00000198677
TCGA cBioPortalTTC37
AceView (NCBI)TTC37
Genatlas (Paris)TTC37
WikiGenes9652
SOURCE (Princeton)TTC37
Genetics Home Reference (NIH)TTC37
Genomic and cartography
GoldenPath hg38 (UCSC)TTC37  -     chr5:95463895-95555005 -  5q15   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TTC37  -     5q15   [Description]    (hg19-Feb_2009)
EnsemblTTC37 - 5q15 [CytoView hg19]  TTC37 - 5q15 [CytoView hg38]
Mapping of homologs : NCBITTC37 [Mapview hg19]  TTC37 [Mapview hg38]
OMIM222470   614589   
Gene and transcription
Genbank (Entrez)AB002370 AK307531 BC009767 BC015163 BC030966
RefSeq transcript (Entrez)NM_014639
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)TTC37
Cluster EST : UnigeneHs.482868 [ NCBI ]
CGAP (NCI)Hs.482868
Alternative Splicing GalleryENSG00000198677
Gene ExpressionTTC37 [ NCBI-GEO ]   TTC37 [ EBI - ARRAY_EXPRESS ]   TTC37 [ SEEK ]   TTC37 [ MEM ]
Gene Expression Viewer (FireBrowse)TTC37 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)9652
GTEX Portal (Tissue expression)TTC37
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ6PGP7   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ6PGP7  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ6PGP7
Splice isoforms : SwissVarQ6PGP7
PhosPhoSitePlusQ6PGP7
Domaine pattern : Prosite (Expaxy)TPR (PS50005)    TPR_REGION (PS50293)   
Domains : Interpro (EBI)TPR-contain_dom    TPR-like_helical_dom    TPR_repeat   
Domain families : Pfam (Sanger)TPR_8 (PF13181)   
Domain families : Pfam (NCBI)pfam13181   
Domain families : Smart (EMBL)TPR (SM00028)  
Conserved Domain (NCBI)TTC37
DMDM Disease mutations9652
Blocks (Seattle)TTC37
SuperfamilyQ6PGP7
Human Protein AtlasENSG00000198677
Peptide AtlasQ6PGP7
HPRD11079
IPIIPI00005634   IPI00965004   IPI00964739   IPI00967773   IPI00965347   
Protein Interaction databases
DIP (DOE-UCLA)Q6PGP7
IntAct (EBI)Q6PGP7
FunCoupENSG00000198677
BioGRIDTTC37
STRING (EMBL)TTC37
ZODIACTTC37
Ontologies - Pathways
QuickGOQ6PGP7
Ontology : AmiGOprotein binding  nucleus  nucleoplasm  cytoplasm  cytosol  cytosol  transcriptionally active chromatin  exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay  Ski complex  
Ontology : EGO-EBIprotein binding  nucleus  nucleoplasm  cytoplasm  cytosol  cytosol  transcriptionally active chromatin  exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay  Ski complex  
Pathways : KEGGRNA degradation   
NDEx NetworkTTC37
Atlas of Cancer Signalling NetworkTTC37
Wikipedia pathwaysTTC37
Orthology - Evolution
OrthoDB9652
GeneTree (enSembl)ENSG00000198677
Phylogenetic Trees/Animal Genes : TreeFamTTC37
HOVERGENQ6PGP7
HOGENOMQ6PGP7
Homologs : HomoloGeneTTC37
Homology/Alignments : Family Browser (UCSC)TTC37
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTTC37 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TTC37
dbVarTTC37
ClinVarTTC37
1000_GenomesTTC37 
Exome Variant ServerTTC37
ExAC (Exome Aggregation Consortium)TTC37 (select the gene name)
Genetic variants : HAPMAP9652
Genomic Variants (DGV)TTC37 [DGVbeta]
DECIPHERTTC37 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTTC37 
Mutations
ICGC Data PortalTTC37 
TCGA Data PortalTTC37 
Broad Tumor PortalTTC37
OASIS PortalTTC37 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTTC37  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDTTC37
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)Mendelian genes
BioMutasearch TTC37
DgiDB (Drug Gene Interaction Database)TTC37
DoCM (Curated mutations)TTC37 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)TTC37 (select a term)
intoGenTTC37
Cancer3DTTC37(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM222470    614589   
Orphanet11605   
MedgenTTC37
Genetic Testing Registry TTC37
NextProtQ6PGP7 [Medical]
TSGene9652
GENETestsTTC37
Target ValidationTTC37
Huge Navigator TTC37 [HugePedia]
snp3D : Map Gene to Disease9652
BioCentury BCIQTTC37
ClinGenTTC37
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD9652
Chemical/Pharm GKB GenePA162407226
Clinical trialTTC37
Miscellaneous
canSAR (ICR)TTC37 (select the gene name)
Probes
Litterature
PubMed20 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTTC37
EVEXTTC37
GoPubMedTTC37
iHOPTTC37
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed May 31 15:47:33 CEST 2017

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