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TTC37 (tetratricopeptide repeat domain 37)

Identity

Alias (NCBI)KIAA0372
Ski3
THES
HGNC (Hugo) TTC37
HGNC Alias symbTHES
HGNC Alias namethespin
HGNC Previous nameKIAA0372
HGNC Previous nameKIAA0372
LocusID (NCBI) 9652
Atlas_Id 75289
Location 5q15  [Link to chromosome band 5q15]
Location_base_pair Starts at 95463894 and ends at 95554977 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
NOS2 (17q11.2) / TTC37 (5q15)NQO1 (16q22.1) / TTC37 (5q15)NUDT10 (Xp11.22) / TTC37 (5q15)
RNPC3 (1p21.1) / TTC37 (5q15)SLC36A1 (5q33.1) / TTC37 (5q15)TTC37 (5q15) / MFSD4A (1q32.1)
TTC37 (5q15) / RBPMS (8p12)TTC37 (5q15) / RPL30 (8q22.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)TTC37   23639
LRG (Locus Reference Genomic)LRG_173
Cards
Entrez_Gene (NCBI)TTC37    tetratricopeptide repeat domain 37
AliasesKIAA0372; Ski3; THES
GeneCards (Weizmann)TTC37
Ensembl hg19 (Hinxton)ENSG00000198677 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000198677 [Gene_View]  ENSG00000198677 [Sequence]  chr5:95463894-95554977 [Contig_View]  TTC37 [Vega]
ICGC DataPortalENSG00000198677
TCGA cBioPortalTTC37
AceView (NCBI)TTC37
Genatlas (Paris)TTC37
SOURCE (Princeton)TTC37
Genetics Home Reference (NIH)TTC37
Genomic and cartography
GoldenPath hg38 (UCSC)TTC37  -     chr5:95463894-95554977 -  5q15   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TTC37  -     5q15   [Description]    (hg19-Feb_2009)
GoldenPathTTC37 - 5q15 [CytoView hg19]  TTC37 - 5q15 [CytoView hg38]
ImmunoBaseENSG00000198677
Genome Data Viewer NCBITTC37 [Mapview hg19]  
OMIM222470   614589   
Gene and transcription
Genbank (Entrez)AB002370 AK307531 BC009767 BC015163 BC030966
RefSeq transcript (Entrez)NM_014639
Consensus coding sequences : CCDS (NCBI)TTC37
Gene ExpressionTTC37 [ NCBI-GEO ]   TTC37 [ EBI - ARRAY_EXPRESS ]   TTC37 [ SEEK ]   TTC37 [ MEM ]
Gene Expression Viewer (FireBrowse)TTC37 [ Firebrowse - Broad ]
GenevisibleExpression of TTC37 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)9652
GTEX Portal (Tissue expression)TTC37
Human Protein AtlasENSG00000198677-TTC37 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ6PGP7   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ6PGP7  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ6PGP7
PhosPhoSitePlusQ6PGP7
Domaine pattern : Prosite (Expaxy)TPR (PS50005)    TPR_REGION (PS50293)   
Domains : Interpro (EBI)Ski3/TTC37    TPR-contain_dom    TPR-like_helical_dom_sf    TPR_repeat   
Domain families : Pfam (Sanger)TPR_8 (PF13181)   
Domain families : Pfam (NCBI)pfam13181   
Domain families : Smart (EMBL)TPR (SM00028)  
Conserved Domain (NCBI)TTC37
SuperfamilyQ6PGP7
AlphaFold pdb e-kbQ6PGP7   
Human Protein Atlas [tissue]ENSG00000198677-TTC37 [tissue]
HPRD11079
Protein Interaction databases
DIP (DOE-UCLA)Q6PGP7
IntAct (EBI)Q6PGP7
BioGRIDTTC37
STRING (EMBL)TTC37
ZODIACTTC37
Ontologies - Pathways
QuickGOQ6PGP7
Ontology : AmiGOprotein binding  nucleus  nucleoplasm  cytoplasm  cytosol  cytosol  nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'  transcriptionally active chromatin  exonucleolytic catabolism of deadenylated mRNA  Ski complex  Ski complex  
Ontology : EGO-EBIprotein binding  nucleus  nucleoplasm  cytoplasm  cytosol  cytosol  nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'  transcriptionally active chromatin  exonucleolytic catabolism of deadenylated mRNA  Ski complex  Ski complex  
NDEx NetworkTTC37
Atlas of Cancer Signalling NetworkTTC37
Wikipedia pathwaysTTC37
Orthology - Evolution
OrthoDB9652
GeneTree (enSembl)ENSG00000198677
Phylogenetic Trees/Animal Genes : TreeFamTTC37
Homologs : HomoloGeneTTC37
Homology/Alignments : Family Browser (UCSC)TTC37
Gene fusions - Rearrangements
Fusion : QuiverTTC37
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTTC37 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TTC37
dbVarTTC37
ClinVarTTC37
MonarchTTC37
1000_GenomesTTC37 
Exome Variant ServerTTC37
GNOMAD BrowserENSG00000198677
Varsome BrowserTTC37
ACMGTTC37 variants
VarityQ6PGP7
Genomic Variants (DGV)TTC37 [DGVbeta]
DECIPHERTTC37 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTTC37 
Mutations
ICGC Data PortalTTC37 
TCGA Data PortalTTC37 
Broad Tumor PortalTTC37
OASIS PortalTTC37 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTTC37  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DTTC37
Mutations and Diseases : HGMDTTC37
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaTTC37
DgiDB (Drug Gene Interaction Database)TTC37
DoCM (Curated mutations)TTC37
CIViC (Clinical Interpretations of Variants in Cancer)TTC37
Cancer3DTTC37
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM222470    614589   
Orphanet11605   
DisGeNETTTC37
MedgenTTC37
Genetic Testing Registry TTC37
NextProtQ6PGP7 [Medical]
GENETestsTTC37
Target ValidationTTC37
Huge Navigator TTC37 [HugePedia]
ClinGenTTC37
Clinical trials, drugs, therapy
MyCancerGenomeTTC37
Protein Interactions : CTDTTC37
Pharm GKB GenePA162407226
PharosQ6PGP7
Clinical trialTTC37
Miscellaneous
canSAR (ICR)TTC37
HarmonizomeTTC37
DataMed IndexTTC37
Probes
Litterature
PubMed43 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXTTC37
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 16:27:18 CEST 2021

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