Atlas of Genetics and Cytogenetics in Oncology and Haematology


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TTC4 (tetratricopeptide repeat domain 4)

Identity

Alias_symbol (synonym)MGC5097
FLJ41930
Other alias-
HGNC (Hugo) TTC4
LocusID (NCBI) 7268
Atlas_Id 42723
Location 1p32.3  [Link to chromosome band 1p32]
Location_base_pair Starts at 54715822 and ends at 54742655 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
MROH7 (1p32.3) / TTC4 (1p32.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 1 ]
  Skin: Melanoma


External links

Nomenclature
HGNC (Hugo)TTC4   12394
Cards
Entrez_Gene (NCBI)TTC4  7268  tetratricopeptide repeat domain 4
Aliases
GeneCards (Weizmann)TTC4
Ensembl hg19 (Hinxton)ENSG00000243725 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000243725 [Gene_View]  chr1:54715822-54742655 [Contig_View]  TTC4 [Vega]
ICGC DataPortalENSG00000243725
TCGA cBioPortalTTC4
AceView (NCBI)TTC4
Genatlas (Paris)TTC4
WikiGenes7268
SOURCE (Princeton)TTC4
Genetics Home Reference (NIH)TTC4
Genomic and cartography
GoldenPath hg38 (UCSC)TTC4  -     chr1:54715822-54742655 +  1p32.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TTC4  -     1p32.3   [Description]    (hg19-Feb_2009)
EnsemblTTC4 - 1p32.3 [CytoView hg19]  TTC4 - 1p32.3 [CytoView hg38]
Mapping of homologs : NCBITTC4 [Mapview hg19]  TTC4 [Mapview hg38]
OMIM606753   
Gene and transcription
Genbank (Entrez)AF063602 AF073887 AK025524 AK090964 AK123924
RefSeq transcript (Entrez)NM_001291333 NM_004623
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)TTC4
Cluster EST : UnigeneHs.729029 [ NCBI ]
CGAP (NCI)Hs.729029
Alternative Splicing GalleryENSG00000243725
Gene ExpressionTTC4 [ NCBI-GEO ]   TTC4 [ EBI - ARRAY_EXPRESS ]   TTC4 [ SEEK ]   TTC4 [ MEM ]
Gene Expression Viewer (FireBrowse)TTC4 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)7268
GTEX Portal (Tissue expression)TTC4
Protein : pattern, domain, 3D structure
UniProt/SwissProtO95801   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO95801  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO95801
Splice isoforms : SwissVarO95801
PhosPhoSitePlusO95801
Domaine pattern : Prosite (Expaxy)TPR_REGION (PS50293)   
Domains : Interpro (EBI)TPR-contain_dom    TPR-like_helical_dom    TPR_repeat   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Domain families : Smart (EMBL)TPR (SM00028)  
Conserved Domain (NCBI)TTC4
DMDM Disease mutations7268
Blocks (Seattle)TTC4
SuperfamilyO95801
Human Protein AtlasENSG00000243725
Peptide AtlasO95801
HPRD08417
IPIIPI00000606   IPI00446575   IPI00980272   IPI00514593   
Protein Interaction databases
DIP (DOE-UCLA)O95801
IntAct (EBI)O95801
FunCoupENSG00000243725
BioGRIDTTC4
STRING (EMBL)TTC4
ZODIACTTC4
Ontologies - Pathways
QuickGOO95801
Ontology : AmiGO
Ontology : EGO-EBI
NDEx NetworkTTC4
Atlas of Cancer Signalling NetworkTTC4
Wikipedia pathwaysTTC4
Orthology - Evolution
OrthoDB7268
GeneTree (enSembl)ENSG00000243725
Phylogenetic Trees/Animal Genes : TreeFamTTC4
HOVERGENO95801
HOGENOMO95801
Homologs : HomoloGeneTTC4
Homology/Alignments : Family Browser (UCSC)TTC4
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTTC4 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TTC4
dbVarTTC4
ClinVarTTC4
1000_GenomesTTC4 
Exome Variant ServerTTC4
ExAC (Exome Aggregation Consortium)TTC4 (select the gene name)
Genetic variants : HAPMAP7268
Genomic Variants (DGV)TTC4 [DGVbeta]
DECIPHERTTC4 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTTC4 
Mutations
ICGC Data PortalTTC4 
TCGA Data PortalTTC4 
Broad Tumor PortalTTC4
OASIS PortalTTC4 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTTC4  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDTTC4
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch TTC4
DgiDB (Drug Gene Interaction Database)TTC4
DoCM (Curated mutations)TTC4 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)TTC4 (select a term)
intoGenTTC4
Cancer3DTTC4(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM606753   
Orphanet
MedgenTTC4
Genetic Testing Registry TTC4
NextProtO95801 [Medical]
TSGene7268
GENETestsTTC4
Target ValidationTTC4
Huge Navigator TTC4 [HugePedia]
snp3D : Map Gene to Disease7268
BioCentury BCIQTTC4
ClinGenTTC4
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD7268
Chemical/Pharm GKB GenePA37059
Clinical trialTTC4
Miscellaneous
canSAR (ICR)TTC4 (select the gene name)
Probes
Litterature
PubMed24 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTTC4
EVEXTTC4
GoPubMedTTC4
iHOPTTC4
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed Jun 7 13:01:14 CEST 2017

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