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TTL (tubulin tyrosine ligase)

Identity

HGNC (Hugo) TTL
LocusID (NCBI) 150465
Atlas_Id 55147
Location 2q13
Location_base_pair Starts at 113239743 and ends at 113290222 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
ETV6 (12p13.2) / TTL (2q13)TF (3q22.1) / TTL (2q13)TTL (2q13) / EIF6 (20q11.22)
TTL (2q13) / ETV6 (12p13.2)TTL (2q13) / GPC3 (Xq26.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)TTL   21586
Cards
Entrez_Gene (NCBI)TTL  150465  tubulin tyrosine ligase
GeneCards (Weizmann)TTL
Ensembl hg19 (Hinxton)ENSG00000114999 [Gene_View]  chr2:113239743-113290222 [Contig_View]  TTL [Vega]
Ensembl hg38 (Hinxton)ENSG00000114999 [Gene_View]  chr2:113239743-113290222 [Contig_View]  TTL [Vega]
ICGC DataPortalENSG00000114999
TCGA cBioPortalTTL
AceView (NCBI)TTL
Genatlas (Paris)TTL
WikiGenes150465
SOURCE (Princeton)TTL
Genomic and cartography
GoldenPath hg19 (UCSC)TTL  -     chr2:113239743-113290222 +  2q13   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)TTL  -     2q13   [Description]    (hg38-Dec_2013)
EnsemblTTL - 2q13 [CytoView hg19]  TTL - 2q13 [CytoView hg38]
Mapping of homologs : NCBITTL [Mapview hg19]  TTL [Mapview hg38]
OMIM608291   
Gene and transcription
Genbank (Entrez)AA099055 AB071393 AK026673 AK126378 AK126549
RefSeq transcript (Entrez)NM_153712
RefSeq genomic (Entrez)NC_000002 NC_018913 NT_005403 NW_004929304
Consensus coding sequences : CCDS (NCBI)TTL
Cluster EST : UnigeneHs.358997 [ NCBI ]
CGAP (NCI)Hs.358997
Alternative Splicing GalleryENSG00000114999
Gene ExpressionTTL [ NCBI-GEO ]   TTL [ EBI - ARRAY_EXPRESS ]   TTL [ SEEK ]   TTL [ MEM ]
Gene Expression Viewer (FireBrowse)TTL [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
BioGPS (Tissue expression)150465
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8NG68 (Uniprot)
NextProtQ8NG68  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8NG68
Splice isoforms : SwissVarQ8NG68 (Swissvar)
PhosPhoSitePlusQ8NG68
Domaine pattern : Prosite (Expaxy)TTL (PS51221)   
Domains : Interpro (EBI)TTL/TTLL_fam   
Domain families : Pfam (Sanger)TTL (PF03133)   
Domain families : Pfam (NCBI)pfam03133   
DMDM Disease mutations150465
Blocks (Seattle)TTL
SuperfamilyQ8NG68
Human Protein AtlasENSG00000114999
Peptide AtlasQ8NG68
HPRD12206
IPIIPI00166611   
Protein Interaction databases
DIP (DOE-UCLA)Q8NG68
IntAct (EBI)Q8NG68
FunCoupENSG00000114999
BioGRIDTTL
STRING (EMBL)TTL
ZODIACTTL
Ontologies - Pathways
QuickGOQ8NG68
Ontology : AmiGOmicrotubule cytoskeleton organization  tubulin-tyrosine ligase activity  ATP binding  cellular protein modification process  regulation of axon extension  
Ontology : EGO-EBImicrotubule cytoskeleton organization  tubulin-tyrosine ligase activity  ATP binding  cellular protein modification process  regulation of axon extension  
NDEx Network
Atlas of Cancer Signalling NetworkTTL
Wikipedia pathwaysTTL
Orthology - Evolution
OrthoDB150465
GeneTree (enSembl)ENSG00000114999
Phylogenetic Trees/Animal Genes : TreeFamTTL
Homologs : HomoloGeneTTL
Homology/Alignments : Family Browser (UCSC)TTL
Gene fusions - Rearrangements
Polymorphisms : SNP, variants
NCBI Variation ViewerTTL [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TTL
dbVarTTL
ClinVarTTL
1000_GenomesTTL 
Exome Variant ServerTTL
ExAC (Exome Aggregation Consortium)TTL (select the gene name)
SNP (GeneSNP Utah)TTL
SNP : HGBaseTTL
Genetic variants : HAPMAPTTL
Genomic Variants (DGV)TTL [DGVbeta]
Mutations
ICGC Data PortalTTL 
TCGA Data PortalTTL 
Broad Tumor PortalTTL
OASIS PortalTTL [ Somatic mutations - Copy number]
Cancer Gene: CensusTTL 
Somatic Mutations in Cancer : COSMICTTL 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch TTL
DgiDB (Drug Gene Interaction Database)TTL
DoCM (Curated mutations)TTL (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)TTL (select a term)
intoGenTTL
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] 
Diseases
DECIPHER (Syndromes)2:113239743-113290222
CONAN: Copy Number AnalysisTTL 
Mutations and Diseases : HGMDTTL
OMIM608291   
MedgenTTL
Genetic Testing Registry TTL
NextProtQ8NG68 [Medical]
TSGene150465
GENETestsTTL
Huge Navigator TTL [HugePedia]  TTL [HugeCancerGEM]
snp3D : Map Gene to Disease150465
BioCentury BCIQTTL
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD150465
Chemical/Pharm GKB GenePA134934330
Clinical trialTTL
Miscellaneous
canSAR (ICR)TTL (select the gene name)
Probes
Litterature
PubMed11 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTTL
GoPubMedTTL
iHOPTTL
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Sat Apr 16 18:08:44 CEST 2016

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